BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 30576625)

  • 1. Pathogenic potential of human SLC12A5 variants causing KCC2 dysfunction.
    Fukuda A; Watanabe M
    Brain Res; 2019 May; 1710():1-7. PubMed ID: 30576625
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K
    Tillman L; Zhang J
    Biomed Res Int; 2019; 2019():8941046. PubMed ID: 31240228
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The KCC2 Cotransporter and Human Epilepsy: Getting Excited About Inhibition.
    Kahle KT; Khanna AR; Duan J; Staley KJ; Delpire E; Poduri A
    Neuroscientist; 2016 Dec; 22(6):555-562. PubMed ID: 27130838
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neuronal K
    McMoneagle E; Zhou J; Zhang S; Huang W; Josiah SS; Ding K; Wang Y; Zhang J
    Acta Pharmacol Sin; 2024 Jan; 45(1):1-22. PubMed ID: 37704745
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival.
    Watanabe M; Zhang J; Mansuri MS; Duan J; Karimy JK; Delpire E; Alper SL; Lifton RP; Fukuda A; Kahle KT
    Sci Signal; 2019 Oct; 12(603):. PubMed ID: 31615901
    [TBL] [Abstract][Full Text] [Related]  

  • 6. WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons.
    Friedel P; Kahle KT; Zhang J; Hertz N; Pisella LI; Buhler E; Schaller F; Duan J; Khanna AR; Bishop PN; Shokat KM; Medina I
    Sci Signal; 2015 Jun; 8(383):ra65. PubMed ID: 26126716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Impaired neuronal KCC2 function by biallelic SLC12A5 mutations in migrating focal seizures and severe developmental delay.
    Saitsu H; Watanabe M; Akita T; Ohba C; Sugai K; Ong WP; Shiraishi H; Yuasa S; Matsumoto H; Beng KT; Saitoh S; Miyatake S; Nakashima M; Miyake N; Kato M; Fukuda A; Matsumoto N
    Sci Rep; 2016 Jul; 6():30072. PubMed ID: 27436767
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons.
    Mavrovic M; Uvarov P; Delpire E; Vutskits L; Kaila K; Puskarjov M
    EMBO Rep; 2020 Apr; 21(4):e48880. PubMed ID: 32064760
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures.
    Stödberg T; McTague A; Ruiz AJ; Hirata H; Zhen J; Long P; Farabella I; Meyer E; Kawahara A; Vassallo G; Stivaros SM; Bjursell MK; Stranneheim H; Tigerschiöld S; Persson B; Bangash I; Das K; Hughes D; Lesko N; Lundeberg J; Scott RC; Poduri A; Scheffer IE; Smith H; Gissen P; Schorge S; Reith ME; Topf M; Kullmann DM; Harvey RJ; Wedell A; Kurian MA
    Nat Commun; 2015 Sep; 6():8038. PubMed ID: 26333769
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcript-specific associations of SLC12A5 (KCC2) in human prefrontal cortex with development, schizophrenia, and affective disorders.
    Tao R; Li C; Newburn EN; Ye T; Lipska BK; Herman MM; Weinberger DR; Kleinman JE; Hyde TM
    J Neurosci; 2012 Apr; 32(15):5216-22. PubMed ID: 22496567
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Expanding Therapeutic Potential of Neuronal KCC2.
    Tang BL
    Cells; 2020 Jan; 9(1):. PubMed ID: 31963584
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2.
    Kahle KT; Deeb TZ; Puskarjov M; Silayeva L; Liang B; Kaila K; Moss SJ
    Trends Neurosci; 2013 Dec; 36(12):726-737. PubMed ID: 24139641
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation.
    Duy PQ; David WB; Kahle KT
    Front Cell Neurosci; 2019; 13():515. PubMed ID: 31803025
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clustering of neuronal K+-Cl- cotransporters in lipid rafts by tyrosine phosphorylation.
    Watanabe M; Wake H; Moorhouse AJ; Nabekura J
    J Biol Chem; 2009 Oct; 284(41):27980-27988. PubMed ID: 19679663
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Therapeutic Potential of Neuronal K-Cl Co-Transporter KCC2 in Huntington's Disease and Its Comorbidities.
    Andrews K; Josiah SS; Zhang J
    Int J Mol Sci; 2020 Nov; 21(23):. PubMed ID: 33266310
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chromosomal localization of SLC12A5/Slc12a5, the human and mouse genes for the neuron-specific K(+)-Cl(-) cotransporter (KCC2) defines a new region of conserved homology.
    Sallinen R; Tornberg J; Putkiranta M; Horelli-Kuitunen N; Airaksinen MS; Wessman M
    Cytogenet Cell Genet; 2001; 94(1-2):67-70. PubMed ID: 11701957
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel pathogenic
    Järvelä V; Hamze M; Komulainen-Ebrahim J; Rahikkala E; Piispala J; Kallio M; Kangas SM; Nickl T; Huttula M; Hinttala R; Uusimaa J; Medina I; Immonen EV
    Front Mol Neurosci; 2024; 17():1372662. PubMed ID: 38660387
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A noninvasive optical approach for assessing chloride extrusion activity of the K-Cl cotransporter KCC2 in neuronal cells.
    Ludwig A; Rivera C; Uvarov P
    BMC Neurosci; 2017 Jan; 18(1):23. PubMed ID: 28143398
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chloride cotransporter KCC2 is essential for GABAergic inhibition in the SCN.
    Olde Engberink AHO; Meijer JH; Michel S
    Neuropharmacology; 2018 Aug; 138():80-86. PubMed ID: 29782876
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Could tuning of the inhibitory tone involve graded changes in neuronal chloride transport?
    Titz S; Sammler EM; Hormuzdi SG
    Neuropharmacology; 2015 Aug; 95():321-31. PubMed ID: 25843644
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.