These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

376 related articles for article (PubMed ID: 30578352)

  • 21. Partial impairment of interleukin-12 (IL-12) and IL-18 signaling in Tyk2-deficient mice.
    Shimoda K; Tsutsui H; Aoki K; Kato K; Matsuda T; Numata A; Takase K; Yamamoto T; Nukina H; Hoshino T; Asano Y; Gondo H; Okamura T; Okamura S; Nakayama K; Nakanishi K; Niho Y; Harada M
    Blood; 2002 Mar; 99(6):2094-9. PubMed ID: 11877284
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2).
    Min X; Ungureanu D; Maxwell S; Hammarén H; Thibault S; Hillert EK; Ayres M; Greenfield B; Eksterowicz J; Gabel C; Walker N; Silvennoinen O; Wang Z
    J Biol Chem; 2015 Nov; 290(45):27261-27270. PubMed ID: 26359499
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Identification of an indispensable role for tyrosine kinase 2 in CTL-mediated tumor surveillance.
    Simma O; Zebedin E; Neugebauer N; Schellack C; Pilz A; Chang-Rodriguez S; Lingnau K; Weisz E; Putz EM; Pickl WF; Felzmann T; Müller M; Decker T; Sexl V; Stoiber D
    Cancer Res; 2009 Jan; 69(1):203-11. PubMed ID: 19118004
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The Stat3-activating Tyk2 V678F mutant does not up-regulate signaling through the type I interferon receptor but confers ligand hypersensitivity to a homodimeric receptor.
    Gakovic M; Ragimbeau J; Francois V; Constantinescu SN; Pellegrini S
    J Biol Chem; 2008 Jul; 283(27):18522-9. PubMed ID: 18456658
    [TBL] [Abstract][Full Text] [Related]  

  • 25. An important role of Tyk2 in APC function of dendritic cells for priming CD8+ T cells producing IFN-gamma.
    Aizu K; Li W; Yajima T; Arai T; Shimoda K; Nimura Y; Yoshikai Y
    Eur J Immunol; 2006 Nov; 36(11):3060-70. PubMed ID: 17048270
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha.
    Li S; Labrecque S; Gauzzi MC; Cuddihy AR; Wong AH; Pellegrini S; Matlashewski GJ; Koromilas AE
    Oncogene; 1999 Oct; 18(42):5727-37. PubMed ID: 10523853
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Stat4 regulates multiple components of IFN-gamma-inducing signaling pathways.
    Lawless VA; Zhang S; Ozes ON; Bruns HA; Oldham I; Hoey T; Grusby MJ; Kaplan MH
    J Immunol; 2000 Dec; 165(12):6803-8. PubMed ID: 11120802
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2.
    Piganis RA; De Weerd NA; Gould JA; Schindler CW; Mansell A; Nicholson SE; Hertzog PJ
    J Biol Chem; 2011 Sep; 286(39):33811-8. PubMed ID: 21757742
    [TBL] [Abstract][Full Text] [Related]  

  • 29. TYK2 inhibition reduces type 3 immunity and modifies disease progression in murine spondyloarthritis.
    Gracey E; Hromadová D; Lim M; Qaiyum Z; Zeng M; Yao Y; Srinath A; Baglaenko Y; Yeremenko N; Westlin W; Masse C; Müller M; Strobl B; Miao W; Inman RD
    J Clin Invest; 2020 Apr; 130(4):1863-1878. PubMed ID: 32149730
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Tyk2 is a therapeutic target for psoriasis-like skin inflammation.
    Ishizaki M; Muromoto R; Akimoto T; Sekine Y; Kon S; Diwan M; Maeda H; Togi S; Shimoda K; Oritani K; Matsuda T
    Int Immunol; 2014 May; 26(5):257-67. PubMed ID: 24345760
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Interleukin-23 restores immunity to Mycobacterium tuberculosis infection in IL-12p40-deficient mice and is not required for the development of IL-17-secreting T cell responses.
    Wozniak TM; Ryan AA; Britton WJ
    J Immunol; 2006 Dec; 177(12):8684-92. PubMed ID: 17142769
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Induction of beta-R1/I-TAC by interferon-beta requires catalytically active TYK2.
    Rani MR; Gauzzi C; Pellegrini S; Fish EN; Wei T; Ransohoff RM
    J Biol Chem; 1999 Jan; 274(4):1891-7. PubMed ID: 9890942
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Tyk2-signaling plays an important role in host defense against Escherichia coli through IL-23-induced IL-17 production by gammadelta T cells.
    Nakamura R; Shibata K; Yamada H; Shimoda K; Nakayama K; Yoshikai Y
    J Immunol; 2008 Aug; 181(3):2071-5. PubMed ID: 18641345
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Conditional ablation of TYK2 in immunity to viral infection and tumor surveillance.
    Vielnascher RM; Hainzl E; Leitner NR; Rammerstorfer M; Popp D; Witalisz A; Rom R; Karaghiosoff M; Kolbe T; Müller S; Rülicke T; Lassnig C; Strobl B; Müller M
    Transgenic Res; 2014 Jun; 23(3):519-29. PubMed ID: 24696087
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Community analysis of large-scale molecular dynamics simulations elucidated dynamics-driven allostery in tyrosine kinase 2.
    Lesgidou N; Vlassi M
    Proteins; 2024 Apr; 92(4):474-498. PubMed ID: 37950407
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Mendelian susceptibility to mycobacterial disease: recent discoveries.
    Bustamante J
    Hum Genet; 2020 Jun; 139(6-7):993-1000. PubMed ID: 32025907
    [TBL] [Abstract][Full Text] [Related]  

  • 37. JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.
    Slattery ML; Lundgreen A; Kadlubar SA; Bondurant KL; Wolff RK
    Mol Carcinog; 2013 Feb; 52(2):155-66. PubMed ID: 22121102
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27.
    Bosmann M; Strobl B; Kichler N; Rigler D; Grailer JJ; Pache F; Murray PJ; Müller M; Ward PA
    J Leukoc Biol; 2014 Jul; 96(1):123-31. PubMed ID: 24604832
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria.
    Bohlen J; Zhou Q; Philippot Q; Ogishi M; Rinchai D; Nieminen T; Seyedpour S; Parvaneh N; Rezaei N; Yazdanpanah N; Momenilandi M; Conil C; Neehus AL; Schmidt C; Arango-Franco CA; Voyer TL; Khan T; Yang R; Puchan J; Erazo L; Roiuk M; Vatovec T; Janda Z; Bagarić I; Materna M; Gervais A; Li H; Rosain J; Peel JN; Seeleuthner Y; Han JE; L'Honneur AS; Moncada-Vélez M; Martin-Fernandez M; Horesh ME; Kochetkov T; Schmidt M; AlShehri MA; Salo E; Saxen H; ElGhazali G; Yatim A; Soudée C; Sallusto F; Ensser A; Marr N; Zhang P; Bogunovic D; Cobat A; Shahrooei M; Béziat V; Abel L; Wang X; Boisson-Dupuis S; Teleman AA; Bustamante J; Zhang Q; Casanova JL
    Cell; 2023 Nov; 186(23):5114-5134.e27. PubMed ID: 37875108
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Intracellular signal transduction of interferon on the suppression of haematopoietic progenitor cell growth.
    Kato K; Kamezaki K; Shimoda K; Numata A; Haro T; Aoki K; Ishikawa F; Takase K; Ariyama H; Matsuda T; Miyamoto T; Nagafuji K; Gondo H; Nakayama K; Harada M
    Br J Haematol; 2003 Nov; 123(3):528-35. PubMed ID: 14617019
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.