BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 30578912)

  • 1. Look-alikes may not act alike: Gene expression regulation and cell-type-specific responses of three valproic acid analogues in the neural embryonic stem cell test (ESTn).
    de Leeuw VC; Hessel EVS; Piersma AH
    Toxicol Lett; 2019 Mar; 303():28-37. PubMed ID: 30578912
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcriptomic concentration-response evaluation of valproic acid, cyproconazole, and hexaconazole in the neural embryonic stem cell test (ESTn).
    Theunissen PT; Robinson JF; Pennings JL; de Jong E; Claessen SM; Kleinjans JC; Piersma AH
    Toxicol Sci; 2012 Feb; 125(2):430-8. PubMed ID: 22045034
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential effects of fluoxetine and venlafaxine in the neural embryonic stem cell test (ESTn) revealed by a cell lineage map.
    de Leeuw VC; Hessel EVS; Pennings JLA; Hodemaekers HM; Wackers PFK; van Oostrom CTM; Piersma AH
    Neurotoxicology; 2020 Jan; 76():1-9. PubMed ID: 31593710
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neural crest related gene transcript regulation by valproic acid analogues in the cardiac embryonic stem cell test.
    Mennen RHG; Pennings JLAJ; Piersma AHA
    Reprod Toxicol; 2019 Dec; 90():44-52. PubMed ID: 31445079
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exploring the biological domain of the neural embryonic stem cell test (ESTn): Morphogenetic regulators, Hox genes and cell types, and their usefulness as biomarkers for embryotoxicity screening.
    de Leeuw VC; Pennings JLA; Hessel EVS; Piersma AH
    Toxicology; 2021 Apr; 454():152735. PubMed ID: 33636252
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Short-time gene expression response to valproic acid and valproic acid analogs in mouse embryonic stem cells.
    Jergil M; Forsberg M; Salter H; Stockling K; Gustafson AL; Dencker L; Stigson M
    Toxicol Sci; 2011 Jun; 121(2):328-42. PubMed ID: 21427059
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison of gene expression regulation in mouse- and human embryonic stem cell assays during neural differentiation and in response to valproic acid exposure.
    Schulpen SH; Theunissen PT; Pennings JL; Piersma AH
    Reprod Toxicol; 2015 Aug; 56():77-86. PubMed ID: 26072468
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potency ranking of valproic acid analogues as to inhibition of cardiac differentiation of embryonic stem cells in comparison to their in vivo embryotoxicity.
    de Jong E; Doedée AM; Reis-Fernandes MA; Nau H; Piersma AH
    Reprod Toxicol; 2011 May; 31(4):375-82. PubMed ID: 21115111
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Valproic acid induces apoptosis in differentiating hippocampal neurons by the release of tumor necrosis factor-α from activated astrocytes.
    Wang C; Luan Z; Yang Y; Wang Z; Cui Y; Gu G
    Neurosci Lett; 2011 Jun; 497(2):122-7. PubMed ID: 21543053
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct gene expression responses of two anticonvulsant drugs in a novel human embryonic stem cell based neural differentiation assay protocol.
    Schulpen SH; de Jong E; de la Fonteyne LJ; de Klerk A; Piersma AH
    Toxicol In Vitro; 2015 Apr; 29(3):449-57. PubMed ID: 25524013
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Complementary detection of embryotoxic properties of substances in the neural and cardiac embryonic stem cell tests.
    Theunissen PT; Pennings JL; van Dartel DA; Robinson JF; Kleinjans JC; Piersma AH
    Toxicol Sci; 2013 Mar; 132(1):118-30. PubMed ID: 23243006
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Compound-specific effects of diverse neurodevelopmental toxicants on global gene expression in the neural embryonic stem cell test (ESTn).
    Theunissen PT; Robinson JF; Pennings JL; van Herwijnen MH; Kleinjans JC; Piersma AH
    Toxicol Appl Pharmacol; 2012 Aug; 262(3):330-40. PubMed ID: 22634333
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Culture Conditions Affect Chemical-Induced Developmental Toxicity
    de Leeuw VC; van Nieuwland M; Bokkers BGH; Piersma AH
    Altern Lab Anim; 2020 Jul; 48(4):173-183. PubMed ID: 33034509
    [No Abstract]   [Full Text] [Related]  

  • 14. c-Jun Amino-Terminal Kinase is Involved in Valproic Acid-Mediated Neuronal Differentiation of Mouse Embryonic NSCs and Neurite Outgrowth of NSC-Derived Neurons.
    Lu L; Zhou H; Pan B; Li X; Fu Z; Liu J; Shi Z; Chu T; Wei Z; Ning G; Feng S
    Neurochem Res; 2017 Apr; 42(4):1254-1266. PubMed ID: 28321599
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gene Expression Regulation and Pathway Analysis After Valproic Acid and Carbamazepine Exposure in a Human Embryonic Stem Cell-Based Neurodevelopmental Toxicity Assay.
    Schulpen SH; Pennings JL; Piersma AH
    Toxicol Sci; 2015 Aug; 146(2):311-20. PubMed ID: 25979313
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A comparative transcriptomic study on the effects of valproic acid on two different hESCs lines in a neural teratogenicity test system.
    Colleoni S; Galli C; Gaspar JA; Meganathan K; Jagtap S; Hescheler J; Zagoura D; Bremer S; Sachinidis A; Lazzari G
    Toxicol Lett; 2014 Nov; 231(1):38-44. PubMed ID: 25192806
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro characteristics of valproic acid and all-trans-retinoic acid and their combined use in promoting neuronal differentiation while suppressing astrocytic differentiation in neural stem cells.
    Chu T; Zhou H; Wang T; Lu L; Li F; Liu B; Kong X; Feng S
    Brain Res; 2015 Jan; 1596():31-47. PubMed ID: 25463022
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wnt signaling pathway participates in valproic acid-induced neuronal differentiation of neural stem cells.
    Wang L; Liu Y; Li S; Long ZY; Wu YM
    Int J Clin Exp Pathol; 2015; 8(1):578-85. PubMed ID: 25755748
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Valproic acid promotes neuronal differentiation by induction of neuroprogenitors in human bone-marrow mesenchymal stromal cells.
    Jeong SG; Ohn T; Kim SH; Cho GW
    Neurosci Lett; 2013 Oct; 554():22-7. PubMed ID: 24021810
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Valproic acid-induced gene expression responses in rat whole embryo culture and comparison across in vitro developmental and non-developmental models.
    Tonk EC; Robinson JF; Verhoef A; Theunissen PT; Pennings JL; Piersma AH
    Reprod Toxicol; 2013 Nov; 41():57-66. PubMed ID: 23811354
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.