BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

269 related articles for article (PubMed ID: 30590459)

  • 1. Lapatinib-induced annexin A6 upregulation as an adaptive response of triple-negative breast cancer cells to EGFR tyrosine kinase inhibitors.
    Widatalla SE; Korolkova OY; Whalen DS; Goodwin JS; Williams KP; Ochieng J; Sakwe AM
    Carcinogenesis; 2019 Aug; 40(8):998-1009. PubMed ID: 30590459
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exosomal annexin A6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer.
    Li T; Tao Z; Zhu Y; Liu X; Wang L; Du Y; Cao J; Wang B; Zhang J; Hu X
    Cell Death Dis; 2021 Jul; 12(7):684. PubMed ID: 34238922
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reduced annexin A6 expression promotes the degradation of activated epidermal growth factor receptor and sensitizes invasive breast cancer cells to EGFR-targeted tyrosine kinase inhibitors.
    Koumangoye RB; Nangami GN; Thompson PD; Agboto VK; Ochieng J; Sakwe AM
    Mol Cancer; 2013 Dec; 12(1):167. PubMed ID: 24354805
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypoxia-Inducible Expression of Annexin A6 Enhances the Resistance of Triple-Negative Breast Cancer Cells to EGFR and AR Antagonists.
    Williams SD; Smith TM; Stewart LV; Sakwe AM
    Cells; 2022 Sep; 11(19):. PubMed ID: 36230969
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Diverse Roles of Annexin A6 in Triple-Negative Breast Cancer Diagnosis, Prognosis and EGFR-Targeted Therapies.
    Korolkova OY; Widatalla SE; Williams SD; Whalen DS; Beasley HK; Ochieng J; Grewal T; Sakwe AM
    Cells; 2020 Aug; 9(8):. PubMed ID: 32784650
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Annexin A6 improves anti-migratory and anti-invasive properties of tyrosine kinase inhibitors in EGFR overexpressing human squamous epithelial cells.
    Hoque M; Elmaghrabi YA; Köse M; Beevi SS; Jose J; Meneses-Salas E; Blanco-Muñoz P; Conway JRW; Swarbrick A; Timpson P; Tebar F; Enrich C; Rentero C; Grewal T
    FEBS J; 2020 Jul; 287(14):2961-2978. PubMed ID: 31869496
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy.
    McLaughlin RP; He J; van der Noord VE; Redel J; Foekens JA; Martens JWM; Smid M; Zhang Y; van de Water B
    Breast Cancer Res; 2019 Jul; 21(1):77. PubMed ID: 31262335
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of Met.
    Mueller KL; Madden JM; Zoratti GL; Kuperwasser C; List K; Boerner JL
    Breast Cancer Res; 2012 Jul; 14(4):R104. PubMed ID: 22788954
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacotranscriptomic profiling of resistant triple-negative breast cancer cells treated with lapatinib and berberine shows upregulation of PI3K/Akt signaling under cytotoxic stress.
    Jabbarzadeh Kaboli P; Luo S; Chen Y; Jomhori M; Imani S; Xiang S; Wu Z; Li M; Shen J; Zhao Y; Wu X; Hin Cho C; Xiao Z
    Gene; 2022 Mar; 816():146171. PubMed ID: 35026293
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of PI3K/Akt/mTOR overcomes cisplatin resistance in the triple negative breast cancer cell line HCC38.
    Gohr K; Hamacher A; Engelke LH; Kassack MU
    BMC Cancer; 2017 Nov; 17(1):711. PubMed ID: 29100507
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-EGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triple-negative breast cancer.
    El Guerrab A; Bamdad M; Kwiatkowski F; Bignon YJ; Penault-Llorca F; Aubel C
    Oncotarget; 2016 Nov; 7(45):73618-73637. PubMed ID: 27655662
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of PRMT1 in EGFR methylation and signaling in MDA-MB-468 triple-negative breast cancer cells.
    Nakai K; Xia W; Liao HW; Saito M; Hung MC; Yamaguchi H
    Breast Cancer; 2018 Jan; 25(1):74-80. PubMed ID: 28643125
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Annexin A6 is a scaffold for PKCα to promote EGFR inactivation.
    Koese M; Rentero C; Kota BP; Hoque M; Cairns R; Wood P; Vilà de Muga S; Reverter M; Alvarez-Guaita A; Monastyrskaya K; Hughes WE; Swarbrick A; Tebar F; Daly RJ; Enrich C; Grewal T
    Oncogene; 2013 Jun; 32(23):2858-72. PubMed ID: 22797061
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Implication of calcium activated RasGRF2 in Annexin A6-mediated breast tumor cell growth and motility.
    Whalen DS; Widatalla SE; Korolkova OY; Nangami GS; Beasley HK; Williams SD; Virgous C; Lehmann BD; Ochieng J; Sakwe AM
    Oncotarget; 2019 Jan; 10(2):133-151. PubMed ID: 30719209
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lapatinib increases motility of triple-negative breast cancer cells by decreasing miRNA-7 and inducing Raf-1/MAPK-dependent interleukin-6.
    Hsiao YC; Yeh MH; Chen YJ; Liu JF; Tang CH; Huang WC
    Oncotarget; 2015 Nov; 6(35):37965-78. PubMed ID: 26513016
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis.
    Verma N; Müller AK; Kothari C; Panayotopoulou E; Kedan A; Selitrennik M; Mills GB; Nguyen LK; Shin S; Karn T; Holtrich U; Lev S
    Cancer Res; 2017 Jan; 77(1):86-99. PubMed ID: 27793840
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lapatinib inhibits CIP2A/PP2A/p-Akt signaling and induces apoptosis in triple negative breast cancer cells.
    Liu CY; Hu MH; Hsu CJ; Huang CT; Wang DS; Tsai WC; Chen YT; Lee CH; Chu PY; Hsu CC; Chen MH; Shiau CW; Tseng LM; Chen KF
    Oncotarget; 2016 Feb; 7(8):9135-49. PubMed ID: 26824320
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SUMOylation of AnxA6 facilitates EGFR-PKCα complex formation to suppress epithelial cancer growth.
    Sheng Z; Cao X; Deng YN; Zhao X; Liang S
    Cell Commun Signal; 2023 Aug; 21(1):189. PubMed ID: 37528485
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of insulin-like growth factor-binding protein-3 signaling through sphingosine kinase-1 sensitizes triple-negative breast cancer cells to EGF receptor blockade.
    Martin JL; de Silva HC; Lin MZ; Scott CD; Baxter RC
    Mol Cancer Ther; 2014 Feb; 13(2):316-28. PubMed ID: 24337110
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of RPTOR overcomes resistance to EGFR inhibition in triple-negative breast cancer cells.
    You KS; Yi YW; Kwak SJ; Seong YS
    Int J Oncol; 2018 Mar; 52(3):828-840. PubMed ID: 29344641
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.