BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 30591679)

  • 1. Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma.
    Bhuvanalakshmi G; Gamit N; Patil M; Arfuso F; Sethi G; Dharmarajan A; Kumar AP; Warrier S
    Cancers (Basel); 2018 Dec; 11(1):. PubMed ID: 30591679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Netrin-like domain of sFRP4, a Wnt antagonist inhibits stemness, metastatic and invasive properties by specifically blocking MMP-2 in cancer stem cells from human glioma cell line U87MG.
    Yasmin IA; Mohana Sundaram S; Banerjee A; Varier L; Dharmarajan A; Warrier S
    Exp Cell Res; 2021 Dec; 409(2):112912. PubMed ID: 34762897
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherapeutic response of glioma stem-like cells.
    Warrier S; Balu SK; Kumar AP; Millward M; Dharmarajan A
    Oncol Res; 2013; 21(2):93-102. PubMed ID: 24406045
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Secreted frizzled-related protein 4 inhibits glioma stem-like cells by reversing epithelial to mesenchymal transition, inducing apoptosis and decreasing cancer stem cell properties.
    Bhuvanalakshmi G; Arfuso F; Millward M; Dharmarajan A; Warrier S
    PLoS One; 2015; 10(6):e0127517. PubMed ID: 26030909
    [TBL] [Abstract][Full Text] [Related]  

  • 5. iPSC-Derived Glioblastoma Cells Have Enhanced Stemness Wnt/β-Catenin Activity Which Is Negatively Regulated by Wnt Antagonist sFRP4.
    Yasmin IA; Dharmarajan A; Warrier S
    Cancers (Basel); 2023 Jul; 15(14):. PubMed ID: 37509281
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells.
    He B; Lee AY; Dadfarmay S; You L; Xu Z; Reguart N; Mazieres J; Mikami I; McCormick F; Jablons DM
    Cancer Res; 2005 Feb; 65(3):743-8. PubMed ID: 15705870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Secreted Frizzled-related protein 4 (sFRP4) chemo-sensitizes cancer stem cells derived from human breast, prostate, and ovary tumor cell lines.
    Deshmukh A; Kumar S; Arfuso F; Newsholme P; Dharmarajan A
    Sci Rep; 2017 May; 7(1):2256. PubMed ID: 28536422
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Epigenetic demethylation of sFRPs, with emphasis on sFRP4 activation, leading to Wnt signalling suppression and histone modifications in breast, prostate, and ovary cancer stem cells.
    Deshmukh A; Arfuso F; Newsholme P; Dharmarajan A
    Int J Biochem Cell Biol; 2019 Apr; 109():23-32. PubMed ID: 30710752
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4.
    Bhuvanalakshmi G; Basappa ; Rangappa KS; Dharmarajan A; Sethi G; Kumar AP; Warrier S
    Front Pharmacol; 2017; 8():124. PubMed ID: 28373842
    [No Abstract]   [Full Text] [Related]  

  • 10. The inhibitory influence of adipose tissue-derived mesenchymal stem cell environment and Wnt antagonism on breast tumour cell lines.
    Visweswaran M; Arfuso F; Dilley RJ; Newsholme P; Dharmarajan A
    Int J Biochem Cell Biol; 2018 Feb; 95():63-72. PubMed ID: 29277675
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MeCP2 modulates the canonical Wnt pathway activation by targeting SFRP4 in rheumatoid arthritis fibroblast-like synoviocytes in rats.
    Miao CG; Huang C; Huang Y; Yang YY; He X; Zhang L; Lv XW; Jin Y; Li J
    Cell Signal; 2013 Mar; 25(3):598-608. PubMed ID: 23200852
    [TBL] [Abstract][Full Text] [Related]  

  • 12. EZH2 regulates sFRP4 expression without affecting the methylation of sFRP4 promoter DNA in colorectal cancer cell lines.
    Liu Y; Yu J; Xie Y; Li M; Wang F; Zhang J; Qi J
    Exp Ther Med; 2020 Nov; 20(5):33. PubMed ID: 32952624
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RYK promotes the stemness of glioblastoma cells via the WNT/ β-catenin pathway.
    Adamo A; Fiore D; De Martino F; Roscigno G; Affinito A; Donnarumma E; Puoti I; Ricci Vitiani L; Pallini R; Quintavalle C; Condorelli G
    Oncotarget; 2017 Feb; 8(8):13476-13487. PubMed ID: 28086236
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro.
    Horvath LG; Henshall SM; Kench JG; Saunders DN; Lee CS; Golovsky D; Brenner PC; O'Neill GF; Kooner R; Stricker PD; Grygiel JJ; Sutherland RL
    Clin Cancer Res; 2004 Jan; 10(2):615-25. PubMed ID: 14760084
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Placental expression of secreted frizzled related protein-4 in the rat and the impact of glucocorticoid-induced fetal and placental growth restriction.
    Hewitt DP; Mark PJ; Dharmarajan AM; Waddell BJ
    Biol Reprod; 2006 Jul; 75(1):75-81. PubMed ID: 16540541
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antagonizing canonical Wnt signaling pathway by recombinant human sFRP4 purified from E. coli and its implications in cancer therapy.
    Ghoshal A; Ghosh SS
    Mol Cell Biochem; 2016 Jul; 418(1-2):119-35. PubMed ID: 27334754
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Wnt regulator SFRP4 inhibits mesothelioma cell proliferation, migration, and antagonizes Wnt3a via its netrin-like domain.
    Perumal V; Dharmarajan AM; Fox SA
    Int J Oncol; 2017 Jul; 51(1):362-368. PubMed ID: 28534940
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Secreted frizzled-related protein 4 induces gastric cancer progression and resistance to cisplatin and oxaliplatin via β-catenin dysregulation.
    Chen CH; Chen CJ; Huang YC; Huang PS; Chi HC; Chuang HC; Lin MH; Huang TH; Hsu JT; Chen CY
    Chemotherapy; 2023 Dec; ():. PubMed ID: 38071975
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis.
    Surendran K; Schiavi S; Hruska KA
    J Am Soc Nephrol; 2005 Aug; 16(8):2373-84. PubMed ID: 15944336
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/β-catenin pathway and predicts poor survival of glioma patients.
    Zhang J; Cai H; Sun L; Zhan P; Chen M; Zhang F; Ran Y; Wan J
    J Exp Clin Cancer Res; 2018 Sep; 37(1):225. PubMed ID: 30208924
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.