303 related articles for article (PubMed ID: 30595437)
1. The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.
Iwasaki S; Iwasaki W; Takahashi M; Sakamoto A; Watanabe C; Shichino Y; Floor SN; Fujiwara K; Mito M; Dodo K; Sodeoka M; Imataka H; Honma T; Fukuzawa K; Ito T; Ingolia NT
Mol Cell; 2019 Feb; 73(4):738-748.e9. PubMed ID: 30595437
[TBL] [Abstract][Full Text] [Related]
2. Dual targeting of DDX3 and eIF4A by the translation inhibitor rocaglamide A.
Chen M; Asanuma M; Takahashi M; Shichino Y; Mito M; Fujiwara K; Saito H; Floor SN; Ingolia NT; Sodeoka M; Dodo K; Ito T; Iwasaki S
Cell Chem Biol; 2021 Apr; 28(4):475-486.e8. PubMed ID: 33296667
[TBL] [Abstract][Full Text] [Related]
3. Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor.
Iwasaki S; Floor SN; Ingolia NT
Nature; 2016 Jun; 534(7608):558-61. PubMed ID: 27309803
[TBL] [Abstract][Full Text] [Related]
4. Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors.
Chu J; Zhang W; Cencic R; Devine WG; Beglov D; Henkel T; Brown LE; Vajda S; Porco JA; Pelletier J
Cell Chem Biol; 2019 Nov; 26(11):1586-1593.e3. PubMed ID: 31519508
[TBL] [Abstract][Full Text] [Related]
5. Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A.
Naineni SK; Liang J; Hull K; Cencic R; Zhu M; Northcote P; Teesdale-Spittle P; Romo D; Nagar B; Pelletier J
Cell Chem Biol; 2021 Jun; 28(6):825-834.e6. PubMed ID: 33412110
[TBL] [Abstract][Full Text] [Related]
6. FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.
Nguyen TM; Kabotyanski EB; Dou Y; Reineke LC; Zhang P; Zhang XH; Malovannaya A; Jung SY; Mo Q; Roarty KP; Chen Y; Zhang B; Neilson JR; Lloyd RE; Perou CM; Ellis MJ; Rosen JM
Cancer Res; 2018 Aug; 78(15):4229-4240. PubMed ID: 29844125
[TBL] [Abstract][Full Text] [Related]
7. Novel eIF4A1 inhibitors with anti-tumor activity in lymphoma.
Kayastha F; Herrington NB; Kapadia B; Roychowdhury A; Nanaji N; Kellogg GE; Gartenhaus RB
Mol Med; 2022 Sep; 28(1):101. PubMed ID: 36058921
[TBL] [Abstract][Full Text] [Related]
8. Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A.
Bordeleau ME; Mori A; Oberer M; Lindqvist L; Chard LS; Higa T; Belsham GJ; Wagner G; Tanaka J; Pelletier J
Nat Chem Biol; 2006 Apr; 2(4):213-20. PubMed ID: 16532013
[TBL] [Abstract][Full Text] [Related]
9. Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase.
Ernst JT; Thompson PA; Nilewski C; Sprengeler PA; Sperry S; Packard G; Michels T; Xiang A; Tran C; Wegerski CJ; Eam B; Young NP; Fish S; Chen J; Howard H; Staunton J; Molter J; Clarine J; Nevarez A; Chiang GG; Appleman JR; Webster KR; Reich SH
J Med Chem; 2020 Jun; 63(11):5879-5955. PubMed ID: 32470302
[TBL] [Abstract][Full Text] [Related]
10. 1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties.
Nilewski C; Michels TD; Packard GK; Xiang AX; Sprengeler PA; Eam B; Fish S; Thompson PA; Wegerski CJ; Nevarez A; Clarine J; Sperry S; Ernst JT; Reich SH
Bioorg Med Chem Lett; 2021 Sep; 47():128111. PubMed ID: 34353608
[TBL] [Abstract][Full Text] [Related]
11. Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation.
Bordeleau ME; Matthews J; Wojnar JM; Lindqvist L; Novac O; Jankowsky E; Sonenberg N; Northcote P; Teesdale-Spittle P; Pelletier J
Proc Natl Acad Sci U S A; 2005 Jul; 102(30):10460-5. PubMed ID: 16030146
[TBL] [Abstract][Full Text] [Related]
12. Strategic Diastereoselective C1 Functionalization in the Aza-Rocaglamide Scaffold toward Natural Product-Inspired eIF4A Inhibitors.
Nilewski C; Michels TD; Xiang AX; Packard GK; Sprengeler PA; Eam B; Fish S; Thompson PA; Wegerski CJ; Ernst JT; Reich SH
Org Lett; 2020 Aug; 22(16):6257-6261. PubMed ID: 32806219
[TBL] [Abstract][Full Text] [Related]
13. eIF4A inhibitors PatA and RocA stack the deck against translation.
Ingolia NT
Structure; 2021 Jul; 29(7):638-639. PubMed ID: 34214439
[TBL] [Abstract][Full Text] [Related]
14. Reanalysis of ribosome profiling datasets reveals a function of rocaglamide A in perturbing the dynamics of translation elongation via eIF4A.
Li F; Fang J; Yu Y; Hao S; Zou Q; Zeng Q; Yang X
Nat Commun; 2023 Feb; 14(1):553. PubMed ID: 36725859
[TBL] [Abstract][Full Text] [Related]
15. Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (-) and the eIF4A-inhibitor Silvestrol.
Müller C; Obermann W; Schulte FW; Lange-Grünweller K; Oestereich L; Elgner F; Glitscher M; Hildt E; Singh K; Wendel HG; Hartmann RK; Ziebuhr J; Grünweller A
Antiviral Res; 2020 Mar; 175():104706. PubMed ID: 31931103
[TBL] [Abstract][Full Text] [Related]
16. RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation.
Bordeleau ME; Cencic R; Lindqvist L; Oberer M; Northcote P; Wagner G; Pelletier J
Chem Biol; 2006 Dec; 13(12):1287-95. PubMed ID: 17185224
[TBL] [Abstract][Full Text] [Related]
17. Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI.
Zakowicz H; Yang HS; Stark C; Wlodawer A; Laronde-Leblanc N; Colburn NH
RNA; 2005 Mar; 11(3):261-74. PubMed ID: 15661843
[TBL] [Abstract][Full Text] [Related]
18. Structural basis for the enhancement of eIF4A helicase activity by eIF4G.
Oberer M; Marintchev A; Wagner G
Genes Dev; 2005 Sep; 19(18):2212-23. PubMed ID: 16166382
[TBL] [Abstract][Full Text] [Related]
19. Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions.
Steinberger J; Shen L; J Kiniry S; Naineni SK; Cencic R; Amiri M; Aboushawareb SAE; Chu J; Maïga RI; Yachnin BJ; Robert F; Sonenberg N; Baranov PV; Pelletier J
Nucleic Acids Res; 2020 Sep; 48(17):9521-9537. PubMed ID: 32766783
[TBL] [Abstract][Full Text] [Related]
20. Structural analysis of the DAP5 MIF4G domain and its interaction with eIF4A.
Virgili G; Frank F; Feoktistova K; Sawicki M; Sonenberg N; Fraser CS; Nagar B
Structure; 2013 Apr; 21(4):517-27. PubMed ID: 23478064
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
