248 related articles for article (PubMed ID: 30598504)
1. Membrane-associated epithelial cell adhesion molecule is slowly cleaved by γ-secretase prior to efficient proteasomal degradation of its intracellular domain.
Huang Y; Chanou A; Kranz G; Pan M; Kohlbauer V; Ettinger A; Gires O
J Biol Chem; 2019 Mar; 294(9):3051-3064. PubMed ID: 30598504
[TBL] [Abstract][Full Text] [Related]
2. Regulated intramembrane proteolysis and degradation of murine epithelial cell adhesion molecule mEpCAM.
Hachmeister M; Bobowski KD; Hogl S; Dislich B; Fukumori A; Eggert C; Mack B; Kremling H; Sarrach S; Coscia F; Zimmermann W; Steiner H; Lichtenthaler SF; Gires O
PLoS One; 2013; 8(8):e71836. PubMed ID: 24009667
[TBL] [Abstract][Full Text] [Related]
3. Cleavage and cell adhesion properties of human epithelial cell adhesion molecule (HEPCAM).
Tsaktanis T; Kremling H; Pavšič M; von Stackelberg R; Mack B; Fukumori A; Steiner H; Vielmuth F; Spindler V; Huang Z; Jakubowski J; Stoecklein NH; Luxenburger E; Lauber K; Lenarčič B; Gires O
J Biol Chem; 2015 Oct; 290(40):24574-91. PubMed ID: 26292218
[TBL] [Abstract][Full Text] [Related]
4. The Coxsackievirus and Adenovirus Receptor (CAR) undergoes ectodomain shedding and regulated intramembrane proteolysis (RIP).
Houri N; Huang KC; Nalbantoglu J
PLoS One; 2013; 8(8):e73296. PubMed ID: 24015300
[TBL] [Abstract][Full Text] [Related]
5. Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis.
Chen AC; Kim S; Shepardson N; Patel S; Hong S; Selkoe DJ
J Cell Biol; 2015 Dec; 211(6):1157-76. PubMed ID: 26694839
[TBL] [Abstract][Full Text] [Related]
6. A high-content screen for small-molecule regulators of epithelial cell-adhesion molecule (EpCAM) cleavage yields a robust inhibitor.
Tretter JY; Schorpp K; Luxenburger E; Trambauer J; Steiner H; Hadian K; Gires O; Niessing D
J Biol Chem; 2018 Jun; 293(23):8994-9005. PubMed ID: 29700109
[TBL] [Abstract][Full Text] [Related]
7. Regulated intramembrane proteolysis of the interleukin-1 receptor II by alpha-, beta-, and gamma-secretase.
Kuhn PH; Marjaux E; Imhof A; De Strooper B; Haass C; Lichtenthaler SF
J Biol Chem; 2007 Apr; 282(16):11982-95. PubMed ID: 17307738
[TBL] [Abstract][Full Text] [Related]
8. Shedding-generated Met receptor fragments can be routed to either the proteasomal or the lysosomal degradation pathway.
Ancot F; Leroy C; Muharram G; Lefebvre J; Vicogne J; Lemiere A; Kherrouche Z; Foveau B; Pourtier A; Melnyk O; Giordano S; Chotteau-Lelievre A; Tulasne D
Traffic; 2012 Sep; 13(9):1261-72. PubMed ID: 22672335
[TBL] [Abstract][Full Text] [Related]
9. Extracellular domain of EpCAM enhances tumor progression through EGFR signaling in colon cancer cells.
Liang KH; Tso HC; Hung SH; Kuan II; Lai JK; Ke FY; Chuang YT; Liu IJ; Wang YP; Chen RH; Wu HC
Cancer Lett; 2018 Oct; 433():165-175. PubMed ID: 29981429
[TBL] [Abstract][Full Text] [Related]
10. C-terminal amino acids in the type I transmembrane domain of L-type lectin VIP36 affect γ-secretase susceptibility.
Hua Z; Watanabe R; Fukunaga T; Matsui Y; Matsuoka M; Yamaguchi S; Tanabe SY; Yamamoto M; Tamura-Kawakami K; Takagi J; Kajita M; Futai E; Shirakabe K
Biochem Biophys Res Commun; 2024 Feb; 696():149504. PubMed ID: 38219489
[TBL] [Abstract][Full Text] [Related]
11. Cleavage of the Interleukin-11 receptor induces processing of its C-terminal fragments by the gamma-secretase and the proteasome.
Lokau J; Flynn CM; Garbers C
Biochem Biophys Res Commun; 2017 Sep; 491(2):296-302. PubMed ID: 28735867
[TBL] [Abstract][Full Text] [Related]
12. Gamma-secretase-dependent signaling of receptor tyrosine kinases.
Merilahti JAM; Elenius K
Oncogene; 2019 Jan; 38(2):151-163. PubMed ID: 30166589
[TBL] [Abstract][Full Text] [Related]
13. Tumor suppressor cell adhesion molecule 1 (CADM1) is cleaved by a disintegrin and metalloprotease 10 (ADAM10) and subsequently cleaved by γ-secretase complex.
Nagara Y; Hagiyama M; Hatano N; Futai E; Suo S; Takaoka Y; Murakami Y; Ito A; Ishiura S
Biochem Biophys Res Commun; 2012 Jan; 417(1):462-7. PubMed ID: 22172944
[TBL] [Abstract][Full Text] [Related]
14. γ-Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling.
Chhibber-Goel J; Coleman-Vaughan C; Agrawal V; Sawhney N; Hickey E; Powell JC; McCarthy JV
J Biol Chem; 2016 Mar; 291(11):5971-5985. PubMed ID: 26755728
[TBL] [Abstract][Full Text] [Related]
15. Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2.
Marron MB; Singh H; Tahir TA; Kavumkal J; Kim HZ; Koh GY; Brindle NP
J Biol Chem; 2007 Oct; 282(42):30509-17. PubMed ID: 17728252
[TBL] [Abstract][Full Text] [Related]
16. Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.
Fleck D; Voss M; Brankatschk B; Giudici C; Hampel H; Schwenk B; Edbauer D; Fukumori A; Steiner H; Kremmer E; Haug-Kröper M; Rossner MJ; Fluhrer R; Willem M; Haass C
J Biol Chem; 2016 Jan; 291(1):318-33. PubMed ID: 26574544
[TBL] [Abstract][Full Text] [Related]
17. Genome-wide screen of gamma-secretase-mediated intramembrane cleavage of receptor tyrosine kinases.
Merilahti JAM; Ojala VK; Knittle AM; Pulliainen AT; Elenius K
Mol Biol Cell; 2017 Nov; 28(22):3123-3131. PubMed ID: 28904208
[TBL] [Abstract][Full Text] [Related]
18. Posttranslational proteolytic processing of Leda-1/Pianp involves cleavage by MMPs, ADAM10/17 and gamma-secretase.
Biswas S; Adrian M; Weber J; Evdokimov K; Winkler M; Géraud C
Biochem Biophys Res Commun; 2016 Sep; 477(4):661-666. PubMed ID: 27349870
[TBL] [Abstract][Full Text] [Related]
19. Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage.
Wunderlich P; Glebov K; Kemmerling N; Tien NT; Neumann H; Walter J
J Biol Chem; 2013 Nov; 288(46):33027-36. PubMed ID: 24078628
[TBL] [Abstract][Full Text] [Related]
20. Regulation of Mertk Surface Expression via ADAM17 and γ-Secretase Proteolytic Processing.
Lahey KC; Varsanyi C; Wang Z; Aquib A; Gadiyar V; Rodrigues AA; Pulica R; Desind S; Davra V; Calianese DC; Liu D; Cho JH; Kotenko SV; De Lorenzo MS; Birge RB
Int J Mol Sci; 2024 Apr; 25(8):. PubMed ID: 38673989
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
