488 related articles for article (PubMed ID: 30608219)
1. Cross-talk between allosteric and orthosteric binding sites of γ-amino butyric acid type A receptors (GABA
Payghan PV; Nath Roy S; Bhattacharyya D; Ghoshal N
J Biomol Struct Dyn; 2019 Aug; 37(12):3065-3080. PubMed ID: 30608219
[TBL] [Abstract][Full Text] [Related]
2. Probing the molecular basis for affinity/potency- and efficacy-based subtype-selectivity exhibited by benzodiazepine-site modulators at GABA
Söderhielm PC; Balle T; Bak-Nyhus S; Zhang M; Hansen KM; Ahring PK; Jensen AA
Biochem Pharmacol; 2018 Dec; 158():339-358. PubMed ID: 30121248
[TBL] [Abstract][Full Text] [Related]
3. A (beta)-strand in the (gamma)2 subunit lines the benzodiazepine binding site of the GABA A receptor: structural rearrangements detected during channel gating.
Teissére JA; Czajkowski C
J Neurosci; 2001 Jul; 21(14):4977-86. PubMed ID: 11438573
[TBL] [Abstract][Full Text] [Related]
4. Allosteric ligands and their binding sites define γ-aminobutyric acid (GABA) type A receptor subtypes.
Olsen RW
Adv Pharmacol; 2015; 73():167-202. PubMed ID: 25637441
[TBL] [Abstract][Full Text] [Related]
5. Docking of 1,4-benzodiazepines in the alpha1/gamma2 GABA(A) receptor modulator site.
Berezhnoy D; Gibbs TT; Farb DH
Mol Pharmacol; 2009 Aug; 76(2):440-50. PubMed ID: 19483108
[TBL] [Abstract][Full Text] [Related]
6. Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs.
Baur R; Tan KR; Lüscher BP; Gonthier A; Goeldner M; Sigel E
J Neurochem; 2008 Sep; 106(6):2353-63. PubMed ID: 18643789
[TBL] [Abstract][Full Text] [Related]
7. Capturing state-dependent dynamic events of GABAA-receptors: a microscopic look into the structural and functional insights.
Payghan PV; Bera I; Bhattacharyya D; Ghoshal N
J Biomol Struct Dyn; 2016 Aug; 34(8):1818-37. PubMed ID: 26372345
[TBL] [Abstract][Full Text] [Related]
8. Structural mechanisms underlying benzodiazepine modulation of the GABA(A) receptor.
Hanson SM; Czajkowski C
J Neurosci; 2008 Mar; 28(13):3490-9. PubMed ID: 18367615
[TBL] [Abstract][Full Text] [Related]
9. A closer look at the high affinity benzodiazepine binding site on GABAA receptors.
Sigel E; Lüscher BP
Curr Top Med Chem; 2011; 11(2):241-6. PubMed ID: 21189125
[TBL] [Abstract][Full Text] [Related]
10. The GABAA-BZR complex as target for the development of anxiolytic drugs.
Trincavelli ML; Da Pozzo E; Daniele S; Martini C
Curr Top Med Chem; 2012; 12(4):254-69. PubMed ID: 22204488
[TBL] [Abstract][Full Text] [Related]
11. Orthosteric and benzodiazepine cavities of the α
Amundarain MJ; Viso JF; Zamarreño F; Giorgetti A; Costabel M
J Biomol Struct Dyn; 2019 Apr; 37(6):1597-1615. PubMed ID: 29633901
[TBL] [Abstract][Full Text] [Related]
12. Rationalizing the binding and α subtype selectivity of synthesized imidazodiazepines and benzodiazepines at GABAA receptors by using molecular docking studies.
Golani LK; Yeunus Mian M; Ahmed T; Pandey KP; Mondal P; Sharmin D; Rezvanian S; Witkin JM; Cook JM
Bioorg Med Chem Lett; 2022 Apr; 62():128637. PubMed ID: 35218882
[TBL] [Abstract][Full Text] [Related]
13. Identification of transduction elements for benzodiazepine modulation of the GABA(A) receptor: three residues are required for allosteric coupling.
Boileau AJ; Czajkowski C
J Neurosci; 1999 Dec; 19(23):10213-20. PubMed ID: 10575018
[TBL] [Abstract][Full Text] [Related]
14. Analysis of Differential Efficacy and Affinity of GABA
Ain QU; Owen RM; Omoto K; Torella R; Bulusu KC; Pryde DC; Glen RC; Fuchs JE; Bender A
Mol Pharm; 2016 Nov; 13(11):4001-4012. PubMed ID: 27704838
[TBL] [Abstract][Full Text] [Related]
15. Loop-F of the α-subunit determines the pharmacologic profile of novel competitive inhibitors of GABA
Mihalik B; Pálvölgyi A; Bogár F; Megyeri K; Ling I; Barkóczy J; Bartha F; Martinek TA; Gacsályi I; Antoni FA
Eur J Pharmacol; 2017 Mar; 798():129-136. PubMed ID: 28153485
[TBL] [Abstract][Full Text] [Related]
16. Mapping of the benzodiazepine recognition site on GABA(A) receptors.
Sigel E
Curr Top Med Chem; 2002 Aug; 2(8):833-9. PubMed ID: 12171574
[TBL] [Abstract][Full Text] [Related]
17. Molecular dissection of benzodiazepine binding and allosteric coupling using chimeric gamma-aminobutyric acidA receptor subunits.
Boileau AJ; Kucken AM; Evers AR; Czajkowski C
Mol Pharmacol; 1998 Feb; 53(2):295-303. PubMed ID: 9463488
[TBL] [Abstract][Full Text] [Related]
18. Allosteric modulation of GABAA receptors via multiple drug-binding sites.
Sieghart W
Adv Pharmacol; 2015; 72():53-96. PubMed ID: 25600367
[TBL] [Abstract][Full Text] [Related]
19. Antinociceptive Effects of a Novel α2/α3-Subtype Selective GABA
Lewter LA; Fisher JL; Siemian JN; Methuku KR; Poe MM; Cook JM; Li JX
ACS Chem Neurosci; 2017 Jun; 8(6):1305-1312. PubMed ID: 28150939
[TBL] [Abstract][Full Text] [Related]
20. Novel positive allosteric modulators of GABAA receptors: do subtle differences in activity at alpha1 plus alpha5 versus alpha2 plus alpha3 subunits account for dissimilarities in behavioral effects in rats?
Savić MM; Majumder S; Huang S; Edwankar RV; Furtmüller R; Joksimović S; Clayton T; Ramerstorfer J; Milinković MM; Roth BL; Sieghart W; Cook JM
Prog Neuropsychopharmacol Biol Psychiatry; 2010 Mar; 34(2):376-86. PubMed ID: 20074611
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
