BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

347 related articles for article (PubMed ID: 30609275)

  • 1. The impact of GPIbα on platelet-targeted FVIII gene therapy in hemophilia A mice with pre-existing anti-FVIII immunity.
    Chen J; Schroeder JA; Luo X; Montgomery RR; Shi Q
    J Thromb Haemost; 2019 Mar; 17(3):449-459. PubMed ID: 30609275
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The important role of von Willebrand factor in platelet-derived FVIII gene therapy for murine hemophilia A in the presence of inhibitory antibodies.
    Shi Q; Schroeder JA; Kuether EL; Montgomery RR
    J Thromb Haemost; 2015 Jul; 13(7):1301-9. PubMed ID: 25955153
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Immune tolerance induced by platelet-targeted factor VIII gene therapy in hemophilia A mice is CD4 T cell mediated.
    Chen Y; Luo X; Schroeder JA; Chen J; Baumgartner CK; Hu J; Shi Q
    J Thromb Haemost; 2017 Oct; 15(10):1994-2004. PubMed ID: 28799202
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity.
    Shi Q; Fahs SA; Wilcox DA; Kuether EL; Morateck PA; Mareno N; Weiler H; Montgomery RR
    Blood; 2008 Oct; 112(7):2713-21. PubMed ID: 18495954
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lentivirus-mediated platelet gene therapy of murine hemophilia A with pre-existing anti-factor VIII immunity.
    Kuether EL; Schroeder JA; Fahs SA; Cooley BC; Chen Y; Montgomery RR; Wilcox DA; Shi Q
    J Thromb Haemost; 2012 Aug; 10(8):1570-80. PubMed ID: 22632092
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity.
    Chen Y; Schroeder JA; Chen J; Luo X; Baumgartner CK; Montgomery RR; Hu J; Shi Q
    Blood; 2016 Mar; 127(10):1346-54. PubMed ID: 26668132
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Platelet gene therapy corrects the hemophilic phenotype in immunocompromised hemophilia A mice transplanted with genetically manipulated human cord blood stem cells.
    Shi Q; Kuether EL; Chen Y; Schroeder JA; Fahs SA; Montgomery RR
    Blood; 2014 Jan; 123(3):395-403. PubMed ID: 24269957
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pre-existing anti-factor VIII immunity alters therapeutic platelet-targeted factor VIII engraftment following busulfan conditioning through cytotoxic CD8 T cells.
    Jing W; Baumgartner CK; Xue F; Schroeder JA; Shi Q
    J Thromb Haemost; 2023 Mar; 21(3):488-498. PubMed ID: 36696197
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ectopic Expression of FVIII in HPCs and MSCs Derived from hiPSCs with Site-Specific Integration of
    Zhao J; Zhou M; Wang Z; Wu L; Hu Z; Liang D
    Int J Mol Sci; 2022 Jan; 23(2):. PubMed ID: 35054807
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Platelet-Targeted FVIII Gene Therapy Restores Hemostasis and Induces Immune Tolerance for Hemophilia A.
    Cai Y; Shi Q
    Front Immunol; 2020; 11():964. PubMed ID: 32595633
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of a genetically engineered mouse model of hemophilia A with complete deletion of the F8 gene.
    Chao BN; Baldwin WH; Healey JF; Parker ET; Shafer-Weaver K; Cox C; Jiang P; Kanellopoulou C; Lollar P; Meeks SL; Lenardo MJ
    J Thromb Haemost; 2016 Feb; 14(2):346-55. PubMed ID: 26588198
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice.
    Gao C; Schroeder JA; Xue F; Jing W; Cai Y; Scheck A; Subramaniam S; Rao S; Weiler H; Czechowicz A; Shi Q
    Blood Adv; 2019 Sep; 3(18):2700-2711. PubMed ID: 31515232
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vivo enrichment of genetically manipulated platelets corrects the murine hemophilic phenotype and induces immune tolerance even using a low multiplicity of infection.
    Schroeder JA; Chen Y; Fang J; Wilcox DA; Shi Q
    J Thromb Haemost; 2014 Aug; 12(8):1283-93. PubMed ID: 24931217
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lentivirus-mediated platelet-derived factor VIII gene therapy in murine haemophilia A.
    Shi Q; Wilcox DA; Fahs SA; Fang J; Johnson BD; DU LM; Desai D; Montgomery RR
    J Thromb Haemost; 2007 Feb; 5(2):352-61. PubMed ID: 17269937
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Platelet gene therapy by lentiviral gene delivery to hematopoietic stem cells restores hemostasis and induces humoral immune tolerance in FIX(null) mice.
    Chen Y; Schroeder JA; Kuether EL; Zhang G; Shi Q
    Mol Ther; 2014 Jan; 22(1):169-77. PubMed ID: 24042561
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characteristics of the Thrombus Formation in Transgenic Mice with Platelet-Targeted Factor VIII Expression.
    Wang Y; Mao J; Li L; Xiao B; Ruan Z; Liu Y; Zhang G; Wang D; Mi JQ; Fang C; Xi X; Shi X; Wang J
    Thromb Haemost; 2022 May; 122(5):755-766. PubMed ID: 34587639
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hematopoietic stem cells encoding porcine factor VIII induce pro-coagulant activity in hemophilia A mice with pre-existing factor VIII immunity.
    Doering CB; Gangadharan B; Dukart HZ; Spencer HT
    Mol Ther; 2007 Jun; 15(6):1093-9. PubMed ID: 17387335
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies.
    Shi Q; Wilcox DA; Fahs SA; Weiler H; Wells CW; Cooley BC; Desai D; Morateck PA; Gorski J; Montgomery RR
    J Clin Invest; 2006 Jul; 116(7):1974-82. PubMed ID: 16823491
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a novel 14-3-3zeta binding site within the cytoplasmic domain of platelet glycoprotein Ibalpha that plays a key role in regulating the von Willebrand factor binding function of glycoprotein Ib-IX.
    Yuan Y; Zhang W; Yan R; Liao Y; Zhao L; Ruan C; Du X; Dai K
    Circ Res; 2009 Dec; 105(12):1177-85. PubMed ID: 19875727
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancing therapeutic efficacy of in vivo platelet-targeted gene therapy in hemophilia A mice.
    Wang X; Fu RY; Li C; Chen CY; Firrman J; Konkle BA; Zhang J; Li L; Xiao W; Poncz M; Miao CH
    Blood Adv; 2020 Nov; 4(22):5722-5734. PubMed ID: 33216891
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.