BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 30611984)

  • 1. Small molecule inhibition of DDAH1 significantly attenuates triple negative breast cancer cell vasculogenic mimicry in vitro.
    Hulin JA; Tommasi S; Elliot D; Mangoni AA
    Biomed Pharmacother; 2019 Mar; 111():602-612. PubMed ID: 30611984
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MiR-193b regulates breast cancer cell migration and vasculogenic mimicry by targeting dimethylarginine dimethylaminohydrolase 1.
    Hulin JA; Tommasi S; Elliot D; Hu DG; Lewis BC; Mangoni AA
    Sci Rep; 2017 Oct; 7(1):13996. PubMed ID: 29070803
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dimethylarginine dimethylaminohydrolase 1 modulates endothelial cell growth through nitric oxide and Akt.
    Zhang P; Hu X; Xu X; Chen Y; Bache RJ
    Arterioscler Thromb Vasc Biol; 2011 Apr; 31(4):890-7. PubMed ID: 21212404
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dimethylarginine dimethylaminohydrolase-1 (DDAH1) is frequently upregulated in prostate cancer, and its overexpression conveys tumor growth and angiogenesis by metabolizing asymmetric dimethylarginine (ADMA).
    Reddy KRK; Dasari C; Duscharla D; Supriya B; Ram NS; Surekha MV; Kumar JM; Ummanni R
    Angiogenesis; 2018 Feb; 21(1):79-94. PubMed ID: 29150732
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel Cellularly Active Inhibitor Regresses DDAH1 Induced Prostate Tumor Growth by Restraining Tumor Angiogenesis through Targeting DDAH1/ADMA/NOS Pathway.
    Kami Reddy KR; Dasari C; Vandavasi S; Natani S; Supriya B; Jadav SS; Sai Ram N; Kumar JM; Ummanni R
    ACS Comb Sci; 2019 Apr; 21(4):241-256. PubMed ID: 30673277
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine.
    Hu X; Atzler D; Xu X; Zhang P; Guo H; Lu Z; Fassett J; Schwedhelm E; Böger RH; Bache RJ; Chen Y
    Arterioscler Thromb Vasc Biol; 2011 Jul; 31(7):1540-6. PubMed ID: 21493890
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DDAH1 deficiency promotes intracellular oxidative stress and cell apoptosis via a miR-21-dependent pathway in mouse embryonic fibroblasts.
    Zhao C; Li T; Han B; Yue W; Shi L; Wang H; Guo Y; Lu Z
    Free Radic Biol Med; 2016 Mar; 92():50-60. PubMed ID: 26806551
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacokinetic Characterization of the DDAH1 Inhibitors ZST316 and ZST152 in Mice Using a HPLC-MS/MS Method.
    Mangoni AA; Ceruti T; Frapolli R; Russo M; Fichera S; Zucchetti M; Tommasi S
    Molecules; 2022 Feb; 27(3):. PubMed ID: 35164277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of a HPLC-MS/MS Method to Assess the Pharmacokinetics and Tumour Distribution of the Dimethylarginine Dimethylaminohydrolase 1 Inhibitors ZST316 and L-257 in a Xenograft Model of Triple-Negative Breast Cancer in Mice.
    Ceruti T; Frapolli R; Ghilardi C; Decio A; Dellavedova G; Tommasi S; Zucchetti M; Mangoni AA
    Molecules; 2023 Dec; 28(24):. PubMed ID: 38138547
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of Dimethylarginine Dimethylaminohydrolase (DDAH) Enzymes as an Emerging Therapeutic Strategy to Target Angiogenesis and Vasculogenic Mimicry in Cancer.
    Hulin JA; Gubareva EA; Jarzebska N; Rodionov RN; Mangoni AA; Tommasi S
    Front Oncol; 2019; 9():1455. PubMed ID: 31993367
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dimethylarginine dimethylaminohydrolase 1 regulates nerve growth factor-promoted differentiation of PC12 cells in a nitric oxide-dependent but asymmetric dimethylargenine-independent manner.
    Wang S; Hu CP; Yuan Q; Zhang WF; Zhou Z; Nie SD; Jiang JL; Li YJ
    J Neurosci Res; 2012 Jun; 90(6):1209-17. PubMed ID: 22488726
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Active site mutant dimethylarginine dimethylaminohydrolase 1 expression confers an intermediate tumour phenotype in C6 gliomas.
    Boult JK; Walker-Samuel S; Jamin Y; Leiper JM; Whitley GS; Robinson SP
    J Pathol; 2011 Nov; 225(3):344-52. PubMed ID: 21590769
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human dimethylarginine dimethylaminohydrolase 1 inhibition by proton pump inhibitors and the cardiovascular risk marker asymmetric dimethylarginine: in vitro and in vivo significance.
    Tommasi S; Elliot DJ; Hulin JA; Lewis BC; McEvoy M; Mangoni AA
    Sci Rep; 2017 Jun; 7(1):2871. PubMed ID: 28588208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitors of the Hydrolytic Enzyme Dimethylarginine Dimethylaminohydrolase (DDAH): Discovery, Synthesis and Development.
    Murphy RB; Tommasi S; Lewis BC; Mangoni AA
    Molecules; 2016 May; 21(5):. PubMed ID: 27187323
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Repetitive ischemia increases myocardial dimethylarginine dimethylaminohydrolase 1 expression.
    Zhang P; Fassett JT; Zhu G; Li J; Hu X; Xu X; Chen Y; Bache RJ
    Vasc Med; 2017 Jun; 22(3):179-188. PubMed ID: 28145161
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genetic variation in the dimethylarginine dimethylaminohydrolase 1 gene (DDAH1) is related to asymmetric dimethylarginine (ADMA) levels, but not to endothelium-dependent vasodilation.
    Lind L; Ingelsson E; Kumar J; Syvänen AC; Axelsson T; Teerlink T
    Vasc Med; 2013 Aug; 18(4):192-9. PubMed ID: 23892448
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gene transfer of dimethylarginine dimethylaminohydrolase-2 improves the impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells induced by lysophosphatidylcholine.
    Feng M; Liu L; Guo Z; Xiong Y
    Eur J Pharmacol; 2008 Apr; 584(1):49-56. PubMed ID: 18342305
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of DDAH1, but not DDAH2, results in apoptosis of a human trophoblast cell line in response to TRAIL.
    Lumicisi BA; Cartwright JE; Leslie K; Wallace AE; Whitley GS
    Hum Reprod; 2015 Aug; 30(8):1813-9. PubMed ID: 26082478
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dimethylarginine Dimethylaminohydrolase 1 Deficiency Induces the Epithelial to Mesenchymal Transition in Renal Proximal Tubular Epithelial Cells and Exacerbates Kidney Damage in Aged and Diabetic Mice.
    Shi L; Zhao C; Wang H; Lei T; Liu S; Cao J; Lu Z
    Antioxid Redox Signal; 2017 Dec; 27(16):1347-1360. PubMed ID: 28594240
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protection of DDAH2 overexpression against homocysteine-induced impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells.
    Liu LH; Guo Z; Feng M; Wu ZZ; He ZM; Xiong Y
    Cell Physiol Biochem; 2012; 30(6):1413-22. PubMed ID: 23171931
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.