BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

366 related articles for article (PubMed ID: 30612740)

  • 1. METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis.
    Liu S; Hausmann S; Carlson SM; Fuentes ME; Francis JW; Pillai R; Lofgren SM; Hulea L; Tandoc K; Lu J; Li A; Nguyen ND; Caporicci M; Kim MP; Maitra A; Wang H; Wistuba II; Porco JA; Bassik MC; Elias JE; Song J; Topisirovic I; Van Rechem C; Mazur PK; Gozani O
    Cell; 2019 Jan; 176(3):491-504.e21. PubMed ID: 30612740
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates.
    Jakobsson ME; Małecki JM; Halabelian L; Nilges BS; Pinto R; Kudithipudi S; Munk S; Davydova E; Zuhairi FR; Arrowsmith CH; Jeltsch A; Leidel SA; Olsen JV; Falnes PØ
    Nat Commun; 2018 Aug; 9(1):3411. PubMed ID: 30143613
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel N-terminal and Lysine Methyltransferases That Target Translation Elongation Factor 1A in Yeast and Human.
    Hamey JJ; Winter DL; Yagoub D; Overall CM; Hart-Smith G; Wilkins MR
    Mol Cell Proteomics; 2016 Jan; 15(1):164-76. PubMed ID: 26545399
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antibody toolkit to investigate eEF1A methylation dynamics in mRNA translation elongation.
    Mealey-Farr R; Jeong J; Park J; Liu S; Hausmann S; Francis JW; Angulo Ibanez M; Cho J; Chua K; Mazur PK; Gozani O
    J Biol Chem; 2023 Jun; 299(6):104747. PubMed ID: 37094697
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of the biochemical activity and tumor-promoting role of the dual protein methyltransferase METL-13/METTL13 in Caenorhabditis elegans.
    Engelfriet ML; Małecki JM; Forsberg AF; Falnes PØ; Ciosk R
    PLoS One; 2023; 18(6):e0287558. PubMed ID: 37347777
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure, Activity and Function of the Dual Protein Lysine and Protein N-Terminal Methyltransferase METTL13.
    Jakobsson ME
    Life (Basel); 2021 Oct; 11(11):. PubMed ID: 34832997
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A).
    Malecki J; Aileni VK; Ho AYY; Schwarz J; Moen A; Sørensen V; Nilges BS; Jakobsson ME; Leidel SA; Falnes PØ
    Nucleic Acids Res; 2017 May; 45(8):4370-4389. PubMed ID: 28108655
    [TBL] [Abstract][Full Text] [Related]  

  • 8. METTL21B Is a Novel Human Lysine Methyltransferase of Translation Elongation Factor 1A: Discovery by CRISPR/Cas9 Knockout.
    Hamey JJ; Wienert B; Quinlan KGR; Wilkins MR
    Mol Cell Proteomics; 2017 Dec; 16(12):2229-2242. PubMed ID: 28663172
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two novel methyltransferases acting upon eukaryotic elongation factor 1A in Saccharomyces cerevisiae.
    Lipson RS; Webb KJ; Clarke SG
    Arch Biochem Biophys; 2010 Aug; 500(2):137-43. PubMed ID: 20510667
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Saccharomyces cerevisiae Eukaryotic Elongation Factor 1A (eEF1A) Is Methylated at Lys-390 by a METTL21-Like Methyltransferase.
    Jakobsson ME; Davydova E; Małecki J; Moen A; Falnes PØ
    PLoS One; 2015; 10(6):e0131426. PubMed ID: 26115316
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dimethylation of eEF1A at Lysine 55 Plays a Key Role in the Regulation of eEF1A2 on Malignant Cell Functions of Acute Myeloid Leukemia.
    Xiao S; Wang Y; Ma Y; Liu J; Tang C; Deng A; Fang C
    Technol Cancer Res Treat; 2020; 19():1533033820914295. PubMed ID: 32347192
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Potential association of eEF1A dimethylation at lysine 55 in the basal area of Helicobacter pylori-eradicated gastric mucosa with the risk of gastric cancer: a retrospective observational study.
    Hirashita Y; Fukuda M; Kodama M; Tsukamoto Y; Okimoto T; Mizukami K; Kawahara Y; Wada Y; Ozaka S; Togo K; Kinoshita K; Fuchino T; Fukuda K; Okamoto K; Ogawa R; Matsunari O; Honda K; Murakami K
    BMC Gastroenterol; 2022 Nov; 22(1):490. PubMed ID: 36437464
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
    Mazur PK; Reynoird N; Khatri P; Jansen PW; Wilkinson AW; Liu S; Barbash O; Van Aller GS; Huddleston M; Dhanak D; Tummino PJ; Kruger RG; Garcia BA; Butte AJ; Vermeulen M; Sage J; Gozani O
    Nature; 2014 Jun; 510(7504):283-7. PubMed ID: 24847881
    [TBL] [Abstract][Full Text] [Related]  

  • 14. METTL13 facilitates cell growth and metastasis in gastric cancer via an eEF1A/HN1L positive feedback circuit.
    Wu Q; Hu Q; Hai Y; Li Y; Gao Y
    J Cell Commun Signal; 2023 Mar; 17(1):121-135. PubMed ID: 35925508
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Methylation of elongation factor 1A by yeast Efm4 or human eEF1A-KMT2 involves a beta-hairpin recognition motif and crosstalks with phosphorylation.
    Hamey JJ; Nguyen A; Haddad M; Vázquez-Campos X; Pfeiffer PG; Wilkins MR
    J Biol Chem; 2024 Feb; 300(2):105639. PubMed ID: 38199565
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Opposing regulation of the Nα-trimethylase METTL11A by its family members METTL11B and METTL13.
    Parker HV; Schaner Tooley CE
    J Biol Chem; 2023 Apr; 299(4):104588. PubMed ID: 36889590
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: review article.
    Lamberti A; Caraglia M; Longo O; Marra M; Abbruzzese A; Arcari P
    Amino Acids; 2004 Jul; 26(4):443-8. PubMed ID: 15290352
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation.
    Jakobsson ME; Malecki J; Nilges BS; Moen A; Leidel SA; Falnes PØ
    Nucleic Acids Res; 2017 Aug; 45(14):8239-8254. PubMed ID: 28520920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methylation of translation elongation factor 1A by the METTL10-like See1 methyltransferase facilitates tombusvirus replication in yeast and plants.
    Li Z; Gonzalez PA; Sasvari Z; Kinzy TG; Nagy PD
    Virology; 2014 Jan; 448():43-54. PubMed ID: 24314635
    [TBL] [Abstract][Full Text] [Related]  

  • 20. METTL13 is downregulated in bladder carcinoma and suppresses cell proliferation, migration and invasion.
    Zhang Z; Zhang G; Kong C; Zhan B; Dong X; Man X
    Sci Rep; 2016 Jan; 6():19261. PubMed ID: 26763933
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.