BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

92 related articles for article (PubMed ID: 3061462)

  • 1. Inactivation of the ribonucleoside triphosphate reductase from Lactobacillus leichmannii by 2'-chloro-2'-deoxyuridine 5'-triphosphate: a 3'-2' hydrogen transfer during the formation of 3'-keto-2'-deoxyuridine 5'-triphosphate.
    Ashley GW; Harris G; Stubbe JA
    Biochemistry; 1988 Oct; 27(20):7841-5. PubMed ID: 3061462
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivation of the Lactobacillus leichmannii ribonucleoside triphosphate reductase by 2'-chloro-2'-deoxyuridine 5'-triphosphate: stoichiometry of inactivation, site of inactivation, and mechanism of the protein chromophore formation.
    Ashley GW; Harris G; Stubbe J
    Biochemistry; 1988 Jun; 27(12):4305-10. PubMed ID: 3048383
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism of inactivation of Escherichia coli and Lactobacillus leichmannii ribonucleotide reductases by 2'-chloro-2'-deoxynucleotides: evidence for generation of 2-methylene-3(2H)-furanone.
    Harris G; Ator M; Stubbe J
    Biochemistry; 1984 Oct; 23(22):5214-25. PubMed ID: 6391538
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of 3'-[3H]2'-Chloro-2'-deoxyuridine 5'-triphosphate with ribonucleotide reductase from Lactobacillus leichmannii.
    Stubbe J; Smith G; Blakley RL
    J Biol Chem; 1983 Feb; 258(3):1619-24. PubMed ID: 6337141
    [TBL] [Abstract][Full Text] [Related]  

  • 5. On the mechanism of ribonucleoside triphosphate reductase from Lactobacillus leichmannii. Evidence for 3' C--H bond cleavage.
    Stubbe J; Ackles D; Segal R; Blakley RL
    J Biol Chem; 1981 May; 256(10):4843-6. PubMed ID: 7014560
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 2'-Deoxy-2'-halonucleotides as alternate substrates and mechanism-based inactivators of Lactobacillus leichmannii ribonucleotide reductase.
    Harris G; Ashley GW; Robins MJ; Tolman RL; Stubbe J
    Biochemistry; 1987 Apr; 26(7):1895-902. PubMed ID: 3297135
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism of inactivation of Escherichia coli ribonucleotide reductase by 2'-chloro-2'-deoxyuridine 5'-diphosphate: evidence for generation of a 2'-deoxy-3'-ketonucleotide via a net 1,2 hydrogen shift.
    Ator MA; Stubbe J
    Biochemistry; 1985 Dec; 24(25):7214-21. PubMed ID: 3910098
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The mechanism of Lactobacillus leichmannii ribonucleotide reductase. Evidence for 3' carbon-hydrogen bond cleavage and a unique role for coenzyme B12.
    Ashley GW; Harris G; Stubbe J
    J Biol Chem; 1986 Mar; 261(9):3958-64. PubMed ID: 3512563
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Binding of Cob(II)alamin to the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii. Identification of dimethylbenzimidazole as the axial ligand.
    Lawrence CC; Gerfen GJ; Samano V; Nitsche R; Robins MJ; Rétey J; Stubbe J
    J Biol Chem; 1999 Mar; 274(11):7039-42. PubMed ID: 10066759
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Coenzyme B12-dependent ribonucleotide reductase: evidence for the participation of five cysteine residues in ribonucleotide reduction.
    Booker S; Licht S; Broderick J; Stubbe J
    Biochemistry; 1994 Oct; 33(42):12676-85. PubMed ID: 7918494
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The function of adenosylcobalamin in the mechanism of ribonucleoside triphosphate reductase from Lactobacillus leichmannii.
    Lawrence CC; Stubbe J
    Curr Opin Chem Biol; 1998 Oct; 2(5):650-5. PubMed ID: 9818192
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: adenosylcobalamin destruction and formation of a nucleotide-based radical.
    Lohman GJ; Gerfen GJ; Stubbe J
    Biochemistry; 2010 Feb; 49(7):1396-403. PubMed ID: 20088568
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substrate and effector binding to ribonucleoside triphosphate reductase of Lactobacillus leichmannii.
    Chen AK; Bhan A; Hopper S; Abrams R; Franzen JS
    Biochemistry; 1974 Feb; 13(4):654-61. PubMed ID: 4811061
    [No Abstract]   [Full Text] [Related]  

  • 14. Adenosylcobalamin-dependent ribonucleoside triphosphate reductase from Lactobacillus leichmannii. Rapid, improved purification involving dGTP-based affinity chromatography plus biophysical characterization studies demonstrating enhanced, "crystallographic level" purity.
    Suto RK; Whalen MA; Finke RG
    Prep Biochem Biotechnol; 1999 Aug; 29(3):273-309. PubMed ID: 10431931
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gemcitabine 5'-triphosphate is a stoichiometric mechanism-based inhibitor of Lactobacillus leichmannii ribonucleoside triphosphate reductase: evidence for thiyl radical-mediated nucleotide radical formation.
    Silva DJ; Stubbe J; Samano V; Robins MJ
    Biochemistry; 1998 Apr; 37(16):5528-35. PubMed ID: 9548936
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hydrogen abstraction from thiols by adenosyl radicals: chemical precedent for thiyl radical formation, the first catalytic step in ribonucleoside triphosphate reductase from Lactobacillus leichmannii.
    Sirovatka JM; Finke RG
    J Inorg Biochem; 2000 Jan; 78(2):149-60. PubMed ID: 10766338
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ribonucleoside triphosphate reductase from Lactobacillus leichmannii.
    Blakley RL
    Methods Enzymol; 1978; 51():246-59. PubMed ID: 692388
    [No Abstract]   [Full Text] [Related]  

  • 18. Cloning, sequencing, and expression of the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii.
    Booker S; Stubbe J
    Proc Natl Acad Sci U S A; 1993 Sep; 90(18):8352-6. PubMed ID: 8397403
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thermolysis of coenzymes B12 at physiological temperatures: activation parameters for cobalt-carbon bond homolysis and a quantitative analysis of the perturbation of the homolysis equilibrium by the ribonucleoside triphosphate reductase from Lactobacillus leichmannii.
    Brown KL; Zou X
    J Inorg Biochem; 1999; 77(3-4):185-95. PubMed ID: 10643658
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism of B12-dependent ribonucleotide reductase.
    Stubbe JA
    Mol Cell Biochem; 1983; 50(1):25-45. PubMed ID: 6341812
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.