201 related articles for article (PubMed ID: 30616572)
1. Shikonin inhibits cancer cell cycling by targeting Cdc25s.
Zhang S; Gao Q; Li W; Zhu L; Shang Q; Feng S; Jia J; Jia Q; Shen S; Su Z
BMC Cancer; 2019 Jan; 19(1):20. PubMed ID: 30616572
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and biological evaluation of novel naphthoquinone derivatives with CDC25 phosphatase inhibitory activity.
Brun MP; Braud E; Angotti D; Mondésert O; Quaranta M; Montes M; Miteva M; Gresh N; Ducommun B; Garbay C
Bioorg Med Chem; 2005 Aug; 13(16):4871-9. PubMed ID: 15921913
[TBL] [Abstract][Full Text] [Related]
3. Novel hydroxyl naphthoquinones with potent Cdc25 antagonizing and growth inhibitory properties.
Peyregne VP; Kar S; Ham SW; Wang M; Wang Z; Carr BI
Mol Cancer Ther; 2005 Apr; 4(4):595-602. PubMed ID: 15827333
[TBL] [Abstract][Full Text] [Related]
4. Shikonin inhibits TNF-α-induced growth and invasion of rat aortic vascular smooth muscle cells.
Zhang X; Hu W; Wu F; Yuan X; Hu J
Can J Physiol Pharmacol; 2015 Aug; 93(8):615-24. PubMed ID: 26042337
[TBL] [Abstract][Full Text] [Related]
5. Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways.
Chen Y; Zheng L; Liu J; Zhou Z; Cao X; Lv X; Chen F
Int Immunopharmacol; 2014 Aug; 21(2):447-55. PubMed ID: 24905636
[TBL] [Abstract][Full Text] [Related]
6. Shikonin induces cell cycle arrest in human gastric cancer (AGS) by early growth response 1 (Egr1)-mediated p21 gene expression.
Kim SJ; Kim JM; Shim SH; Chang HI
J Ethnopharmacol; 2014 Feb; 151(3):1064-1071. PubMed ID: 24384380
[TBL] [Abstract][Full Text] [Related]
7. Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling.
Li MY; Mi C; Wang KS; Wang Z; Zuo HX; Piao LX; Xu GH; Li X; Ma J; Jin X
Chem Biol Interact; 2017 Aug; 274():58-67. PubMed ID: 28684144
[TBL] [Abstract][Full Text] [Related]
8. Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis.
Ahn J; Won M; Choi JH; Kim YS; Jung CR; Im DS; Kyun ML; Lee K; Song KB; Chung KS
Apoptosis; 2013 Jul; 18(7):870-81. PubMed ID: 23546866
[TBL] [Abstract][Full Text] [Related]
9. Shikonin causes cell-cycle arrest and induces apoptosis by regulating the EGFR-NF-κB signalling pathway in human epidermoid carcinoma A431 cells.
Tian R; Li Y; Gao M
Biosci Rep; 2015 Apr; 35(2):. PubMed ID: 25720435
[TBL] [Abstract][Full Text] [Related]
10. A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death.
Bana E; Sibille E; Valente S; Cerella C; Chaimbault P; Kirsch G; Dicato M; Diederich M; Bagrel D
Mol Carcinog; 2015 Mar; 54(3):229-41. PubMed ID: 24155226
[TBL] [Abstract][Full Text] [Related]
11. Shikonin inhibits thyroid cancer cell growth and invasiveness through targeting major signaling pathways.
Yang Q; Ji M; Guan H; Shi B; Hou P
J Clin Endocrinol Metab; 2013 Dec; 98(12):E1909-17. PubMed ID: 24106286
[TBL] [Abstract][Full Text] [Related]
12. RNA-seq transcriptome analysis of breast cancer cell lines under shikonin treatment.
Lin KH; Huang MY; Cheng WC; Wang SC; Fang SH; Tu HP; Su CC; Hung YL; Liu PL; Chen CS; Wang YT; Li CY
Sci Rep; 2018 Feb; 8(1):2672. PubMed ID: 29422643
[TBL] [Abstract][Full Text] [Related]
13. A novel synthetic inhibitor of CDC25 phosphatases: BN82002.
Brezak MC; Quaranta M; Mondésert O; Galcera MO; Lavergne O; Alby F; Cazales M; Baldin V; Thurieau C; Harnett J; Lanco C; Kasprzyk PG; Prevost GP; Ducommun B
Cancer Res; 2004 May; 64(9):3320-5. PubMed ID: 15126376
[TBL] [Abstract][Full Text] [Related]
14. Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression.
Kabakci Z; Käppeli S; Cantù C; Jensen LD; König C; Toggweiler J; Gentili C; Ribaudo G; Zagotto G; Basler K; Pinna LA; Cozza G; Ferrari S
Sci Rep; 2019 Feb; 9(1):1335. PubMed ID: 30718768
[TBL] [Abstract][Full Text] [Related]
15. LGH00031, a novel ortho-quinonoid inhibitor of cell division cycle 25B, inhibits human cancer cells via ROS generation.
Zhou YB; Feng X; Wang LN; Du JQ; Zhou YY; Yu HP; Zang Y; Li JY; Li J
Acta Pharmacol Sin; 2009 Sep; 30(9):1359-68. PubMed ID: 19730430
[TBL] [Abstract][Full Text] [Related]
16. Shikonin inhibits proliferation of melanoma cells by MAPK pathway-mediated induction of apoptosis.
Lee JH; Han SH; Kim YM; Kim SH; Yoo ES; Woo JS; Jung GH; Jung SH; Kim BS; Jung JY
Biosci Rep; 2021 Jan; 41(1):. PubMed ID: 33403388
[TBL] [Abstract][Full Text] [Related]
17. Discovery and characterization of novel small molecule inhibitors of human Cdc25B dual specificity phosphatase.
Brisson M; Nguyen T; Vogt A; Yalowich J; Giorgianni A; Tobi D; Bahar I; Stephenson CR; Wipf P; Lazo JS
Mol Pharmacol; 2004 Oct; 66(4):824-33. PubMed ID: 15231869
[TBL] [Abstract][Full Text] [Related]
18. Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma.
Gong K; Zhang Z; Chen Y; Shu HB; Li W
Eur J Pharmacol; 2014 Sep; 738():142-52. PubMed ID: 24886888
[TBL] [Abstract][Full Text] [Related]
19. Regulations of miR-183-5p and Snail-Mediated Shikonin-Reduced Epithelial-Mesenchymal Transition in Cervical Cancer Cells.
Tang Q; Liu L; Zhang H; Xiao J; Hann SS
Drug Des Devel Ther; 2020; 14():577-589. PubMed ID: 32103900
[TBL] [Abstract][Full Text] [Related]
20. The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.
Fu Z; Deng B; Liao Y; Shan L; Yin F; Wang Z; Zeng H; Zuo D; Hua Y; Cai Z
BMC Cancer; 2013 Dec; 13():580. PubMed ID: 24314238
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]