335 related articles for article (PubMed ID: 30617196)
1. A natural regulatory mutation in the proximal promoter elevates fetal
Martyn GE; Wienert B; Kurita R; Nakamura Y; Quinlan KGR; Crossley M
Blood; 2019 Feb; 133(8):852-856. PubMed ID: 30617196
[TBL] [Abstract][Full Text] [Related]
2. Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
Ravi NS; Wienert B; Wyman SK; Bell HW; George A; Mahalingam G; Vu JT; Prasad K; Bandlamudi BP; Devaraju N; Rajendiran V; Syedbasha N; Pai AA; Nakamura Y; Kurita R; Narayanasamy M; Balasubramanian P; Thangavel S; Marepally S; Velayudhan SR; Srivastava A; DeWitt MA; Crossley M; Corn JE; Mohankumar KM
Elife; 2022 Feb; 11():. PubMed ID: 35147495
[TBL] [Abstract][Full Text] [Related]
3. Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.
Martyn GE; Wienert B; Yang L; Shah M; Norton LJ; Burdach J; Kurita R; Nakamura Y; Pearson RCM; Funnell APW; Quinlan KGR; Crossley M
Nat Genet; 2018 Apr; 50(4):498-503. PubMed ID: 29610478
[TBL] [Abstract][Full Text] [Related]
4. Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin.
Doerfler PA; Feng R; Li Y; Palmer LE; Porter SN; Bell HW; Crossley M; Pruett-Miller SM; Cheng Y; Weiss MJ
Nat Genet; 2021 Aug; 53(8):1177-1186. PubMed ID: 34341563
[TBL] [Abstract][Full Text] [Related]
5. Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
Topfer SK; Feng R; Huang P; Ly LC; Martyn GE; Blobel GA; Weiss MJ; Quinlan KGR; Crossley M
Blood; 2022 Apr; 139(14):2107-2118. PubMed ID: 35090172
[TBL] [Abstract][Full Text] [Related]
6. Original Research: Generation of non-deletional hereditary persistence of fetal hemoglobin β-globin locus yeast artificial chromosome transgenic mouse models: -175 Black HPFH and -195 Brazilian HPFH.
Braghini CA; Costa FC; Fedosyuk H; Neades RY; Novikova LV; Parker MP; Winefield RD; Peterson KR
Exp Biol Med (Maywood); 2016 Apr; 241(7):697-705. PubMed ID: 26946532
[TBL] [Abstract][Full Text] [Related]
7. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
[TBL] [Abstract][Full Text] [Related]
8. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.
Traxler EA; Yao Y; Wang YD; Woodard KJ; Kurita R; Nakamura Y; Hughes JR; Hardison RC; Blobel GA; Li C; Weiss MJ
Nat Med; 2016 Sep; 22(9):987-90. PubMed ID: 27525524
[TBL] [Abstract][Full Text] [Related]
9. KLF1 drives the expression of fetal hemoglobin in British HPFH.
Wienert B; Martyn GE; Kurita R; Nakamura Y; Quinlan KGR; Crossley M
Blood; 2017 Aug; 130(6):803-807. PubMed ID: 28659276
[TBL] [Abstract][Full Text] [Related]
10. Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype.
Weber L; Frati G; Felix T; Hardouin G; Casini A; Wollenschlaeger C; Meneghini V; Masson C; De Cian A; Chalumeau A; Mavilio F; Amendola M; Andre-Schmutz I; Cereseto A; El Nemer W; Concordet JP; Giovannangeli C; Cavazzana M; Miccio A
Sci Adv; 2020 Feb; 6(7):. PubMed ID: 32917636
[TBL] [Abstract][Full Text] [Related]
11. Mi2β is required for γ-globin gene silencing: temporal assembly of a GATA-1-FOG-1-Mi2 repressor complex in β-YAC transgenic mice.
Costa FC; Fedosyuk H; Chazelle AM; Neades RY; Peterson KR
PLoS Genet; 2012; 8(12):e1003155. PubMed ID: 23284307
[TBL] [Abstract][Full Text] [Related]
12. Synergistic effect of two β globin gene cluster mutations leading to the hereditary persistence of fetal hemoglobin (HPFH) phenotype.
Hariharan P; Sawant M; Gorivale M; Manchanda R; Colah R; Ghosh K; Nadkarni A
Mol Biol Rep; 2017 Oct; 44(5):413-417. PubMed ID: 28879539
[TBL] [Abstract][Full Text] [Related]
13. Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus.
Antoniani C; Meneghini V; Lattanzi A; Felix T; Romano O; Magrin E; Weber L; Pavani G; El Hoss S; Kurita R; Nakamura Y; Cradick TJ; Lundberg AS; Porteus M; Amendola M; El Nemer W; Cavazzana M; Mavilio F; Miccio A
Blood; 2018 Apr; 131(17):1960-1973. PubMed ID: 29519807
[TBL] [Abstract][Full Text] [Related]
14. Genome editing using CRISPR-Cas9 to create the HPFH genotype in HSPCs: An approach for treating sickle cell disease and β-thalassemia.
Ye L; Wang J; Tan Y; Beyer AI; Xie F; Muench MO; Kan YW
Proc Natl Acad Sci U S A; 2016 Sep; 113(38):10661-5. PubMed ID: 27601644
[TBL] [Abstract][Full Text] [Related]
15. Molecular basis of hereditary persistence of fetal hemoglobin.
Forget BG
Ann N Y Acad Sci; 1998 Jun; 850():38-44. PubMed ID: 9668525
[TBL] [Abstract][Full Text] [Related]
16. Binding patterns of BCL11A in the globin and GATA1 loci and characterization of the BCL11A fetal hemoglobin locus.
Jawaid K; Wahlberg K; Thein SL; Best S
Blood Cells Mol Dis; 2010 Aug; 45(2):140-6. PubMed ID: 20542454
[TBL] [Abstract][Full Text] [Related]
17. Retroviral transfer of a human fetal globin gene carrying the -202 G gamma beta (+)-HPFH mutation into the human erythroleukemia line, KMOE.
Stoeckert CJ
Hemoglobin; 1991; 15(4):257-68. PubMed ID: 1723972
[TBL] [Abstract][Full Text] [Related]
18. A single point mutation is the cause of the Greek form of hereditary persistence of fetal haemoglobin.
Berry M; Grosveld F; Dillon N
Nature; 1992 Aug; 358(6386):499-502. PubMed ID: 1379347
[TBL] [Abstract][Full Text] [Related]
19. Functional Analysis of an (A)γ-Globin Gene Promoter Variant (HBG1: g.-225_-222delAGCA) Underlines Its Role in Increasing Fetal Hemoglobin Levels Under Erythropoietic Stress.
Ugrin M; Stojiljkovic M; Zukic B; Klaassen K; Katsila T; Vasiljevic J; Dokmanovic L; Janic D; Patrinos GP; Pavlovic S
Hemoglobin; 2016; 40(1):48-52. PubMed ID: 26575252
[TBL] [Abstract][Full Text] [Related]
20. Nuclear proteins that bind the human gamma-globin gene promoter: alterations in binding produced by point mutations associated with hereditary persistence of fetal hemoglobin.
Gumucio DL; Rood KL; Gray TA; Riordan MF; Sartor CI; Collins FS
Mol Cell Biol; 1988 Dec; 8(12):5310-22. PubMed ID: 2468996
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]