These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 30620384)

  • 1. The role of vascular endothelial growth factor, interleukin 8, and insulinlike growth factor in sustaining autophagic DIRAS3-induced dormant ovarian cancer xenografts.
    Mao W; Peters HL; Sutton MN; Orozco AF; Pang L; Yang H; Lu Z; Bast RC
    Cancer; 2019 Apr; 125(8):1267-1280. PubMed ID: 30620384
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ARHI (DIRAS3) induces autophagy in ovarian cancer cells by downregulating the epidermal growth factor receptor, inhibiting PI3K and Ras/MAP signaling and activating the FOXo3a-mediated induction of Rab7.
    Lu Z; Yang H; Sutton MN; Yang M; Clarke CH; Liao WS; Bast RC
    Cell Death Differ; 2014 Aug; 21(8):1275-89. PubMed ID: 24769729
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ARHI (DIRAS3)-mediated autophagy-associated cell death enhances chemosensitivity to cisplatin in ovarian cancer cell lines and xenografts.
    Washington MN; Suh G; Orozco AF; Sutton MN; Yang H; Wang Y; Mao W; Millward S; Ornelas A; Atkinson N; Liao W; Bast RC; Lu Z
    Cell Death Dis; 2015 Aug; 6(8):e1836. PubMed ID: 26247722
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells.
    Lu Z; Luo RZ; Lu Y; Zhang X; Yu Q; Khare S; Kondo S; Kondo Y; Yu Y; Mills GB; Liao WS; Bast RC
    J Clin Invest; 2008 Dec; 118(12):3917-29. PubMed ID: 19033662
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to anaplastic lymphoma kinase inhibition.
    Blessing AM; Santiago-O'Farrill JM; Mao W; Pang L; Ning J; Pak D; Bollu LR; Rask P; Iles L; Yang H; Tran S; Elmir E; Bartholomeusz G; Langley R; Lu Z; Bast RC
    Cancer; 2020 Aug; 126(15):3579-3592. PubMed ID: 32484926
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells.
    Sutton MN; Yang H; Huang GY; Fu C; Pontikos M; Wang Y; Mao W; Pang L; Yang M; Liu J; Parker-Thornburg J; Lu Z; Bast RC
    Autophagy; 2018; 14(4):637-653. PubMed ID: 29368982
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel.
    Zou CF; Jia L; Jin H; Yao M; Zhao N; Huan J; Lu Z; Bast RC; Feng Y; Yu Y
    BMC Cancer; 2011 Jan; 11():22. PubMed ID: 21244707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cells.
    Lu Z; Baquero MT; Yang H; Yang M; Reger AS; Kim C; Levine DA; Clarke CH; Liao WS; Bast RC
    Autophagy; 2014 Jun; 10(6):1071-92. PubMed ID: 24879154
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression and epigenetic regulation of angiogenesis-related factors during dormancy and recurrent growth of ovarian carcinoma.
    Lyu T; Jia N; Wang J; Yan X; Yu Y; Lu Z; Bast RC; Hua K; Feng W
    Epigenetics; 2013 Dec; 8(12):1330-46. PubMed ID: 24135786
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The tumour suppressor DiRas3 interacts with C-RAF and downregulates MEK activity to restrict cell migration.
    Klingauf M; Beck M; Berge U; Turgay Y; Heinzer S; Horvath P; Kroschewski R
    Biol Cell; 2013 Feb; 105(2):91-107. PubMed ID: 23157514
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinct subgroup of the Ras family member 3 (DIRAS3) expression impairs metastasis and induces autophagy of gastric cancer cells in mice.
    Qiu J; Li X; He Y; Sun D; Li W; Xin Y
    J Cancer Res Clin Oncol; 2018 Oct; 144(10):1869-1886. PubMed ID: 30043279
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models.
    Ornelas A; McCullough CR; Lu Z; Zacharias NM; Kelderhouse LE; Gray J; Yang H; Engel BJ; Wang Y; Mao W; Sutton MN; Bhattacharya PK; Bast RC; Millward SW
    BMC Cancer; 2016 Oct; 16(1):824. PubMed ID: 27784287
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Re-expression of DIRAS3 and p53 induces apoptosis and impaired autophagy in head and neck squamous cell carcinoma.
    Liu Z; Hurst DR; Qu X; Lu LG; Wu CZ; Li YY; Li Y
    Mil Med Res; 2020 Oct; 7(1):48. PubMed ID: 33038921
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the insulin growth factor and the vascular endothelial growth factor pathways in ovarian cancer.
    Shao M; Hollar S; Chambliss D; Schmitt J; Emerson R; Chelladurai B; Perkins S; Ivan M; Matei D
    Mol Cancer Ther; 2012 Jul; 11(7):1576-86. PubMed ID: 22700681
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DIRAS3: An Imprinted Tumor Suppressor Gene that Regulates RAS and PI3K-driven Cancer Growth, Motility, Autophagy, and Tumor Dormancy.
    Bildik G; Liang X; Sutton MN; Bast RC; Lu Z
    Mol Cancer Ther; 2022 Jan; 21(1):25-37. PubMed ID: 34667114
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Weight Loss Upregulates the Small GTPase DIRAS3 in Human White Adipose Progenitor Cells, Which Negatively Regulates Adipogenesis and Activates Autophagy via Akt-mTOR Inhibition.
    Ejaz A; Mitterberger MC; Lu Z; Mattesich M; Zwierzina ME; Hörl S; Kaiser A; Viertler HP; Rostek U; Meryk A; Khalid S; Pierer G; Bast RC; Zwerschke W
    EBioMedicine; 2016 Apr; 6():149-161. PubMed ID: 27211557
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1.
    Sutton MN; Huang GY; Liang X; Sharma R; Reger AS; Mao W; Pang L; Rask PJ; Lee K; Gray JP; Hurwitz AM; Palzkill T; Millward SW; Kim C; Lu Z; Bast RC
    Cancers (Basel); 2019 Apr; 11(4):. PubMed ID: 31003488
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combination of erlotinib and a PARP inhibitor inhibits growth of A2780 tumor xenografts due to increased autophagy.
    Sui H; Shi C; Yan Z; Li H
    Drug Des Devel Ther; 2015; 9():3183-90. PubMed ID: 26124641
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DIRAS3 induces autophagy and enhances sensitivity to anti-autophagic therapy in KRAS-driven pancreatic and ovarian carcinomas.
    Bildik G; Gray JP; Mao W; Yang H; Ozyurt R; Orellana VR; De Wever O; Carey MS; Bast RC; Lu Z
    Autophagy; 2024 Mar; 20(3):675-691. PubMed ID: 38169324
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hexokinase 2 confers resistance to cisplatin in ovarian cancer cells by enhancing cisplatin-induced autophagy.
    Zhang XY; Zhang M; Cong Q; Zhang MX; Zhang MY; Lu YY; Xu CJ
    Int J Biochem Cell Biol; 2018 Feb; 95():9-16. PubMed ID: 29247711
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.