BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 30625324)

  • 1. The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer.
    Zhu Q; Fang L; Heuberger J; Kranz A; Schipper J; Scheckenbach K; Vidal RO; Sunaga-Franze DY; Müller M; Wulf-Goldenberg A; Sauer S; Birchmeier W
    Cell Rep; 2019 Jan; 26(2):415-428.e5. PubMed ID: 30625324
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours.
    Wend P; Fang L; Zhu Q; Schipper JH; Loddenkemper C; Kosel F; Brinkmann V; Eckert K; Hindersin S; Holland JD; Lehr S; Kahn M; Ziebold U; Birchmeier W
    EMBO J; 2013 Jul; 32(14):1977-89. PubMed ID: 23736260
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
    Grinat J; Heuberger J; Vidal RO; Goveas N; Kosel F; Berenguer-Llergo A; Kranz A; Wulf-Goldenberg A; Behrens D; Melcher B; Sauer S; Vieth M; Batlle E; Stewart AF; Birchmeier W
    Nat Commun; 2020 Dec; 11(1):6422. PubMed ID: 33349639
    [TBL] [Abstract][Full Text] [Related]  

  • 4. miR-193a targets MLL1 mRNA and drastically decreases MLL1 protein production: Ectopic expression of the miRNA aberrantly lowers H3K4me3 content of the chromatin and hampers cell proliferation and viability.
    Sengupta D; Deb M; Kar S; Parbin S; Pradhan N; Patra SK
    Gene; 2019 Jul; 705():22-35. PubMed ID: 31005612
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages.
    Carson WF; Cavassani KA; Soares EM; Hirai S; Kittan NA; Schaller MA; Scola MM; Joshi A; Matsukawa A; Aronoff DM; Johnson CN; Dou Y; Gallagher KA; Kunkel SL
    J Immunol; 2017 Sep; 199(5):1865-1874. PubMed ID: 28733487
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.
    Zhou C; Zhang Y; Dai J; Zhou M; Liu M; Wang Y; Chen XZ; Tang J
    Sci Rep; 2016 Feb; 6():22066. PubMed ID: 26902498
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Break the loop, escape the cycle?
    van Amerongen R; Berns A
    EMBO J; 2013 Jul; 32(14):1967-9. PubMed ID: 23749211
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.
    Cao F; Townsend EC; Karatas H; Xu J; Li L; Lee S; Liu L; Chen Y; Ouillette P; Zhu J; Hess JL; Atadja P; Lei M; Qin ZS; Malek S; Wang S; Dou Y
    Mol Cell; 2014 Jan; 53(2):247-61. PubMed ID: 24389101
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex.
    Weirich S; Kudithipudi S; Jeltsch A
    Mol Oncol; 2017 Apr; 11(4):373-387. PubMed ID: 28182322
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Decreased mixed lineage leukemia 1 is involved in endometriosis-related infertility.
    Wen X; Xiong Y; Liu H; Geng T; Jin L; Zhang M; Ma L; Zhang Y
    J Mol Endocrinol; 2021 Jan; 66(1):45-57. PubMed ID: 33151904
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk.
    Wang Q; Trevino LS; Wong RL; Medvedovic M; Chen J; Ho SM; Shen J; Foulds CE; Coarfa C; O'Malley BW; Shilatifard A; Walker CL
    Mol Endocrinol; 2016 Aug; 30(8):856-71. PubMed ID: 27219490
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory T cells.
    Wang T; Guo J; Liping Li ; Jin Q; Zhang F; Hou B; Zhang Y; Zhou X
    Cell Rep; 2024 May; 43(5):114222. PubMed ID: 38735046
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes.
    Wiersma M; Bussiere M; Halsall JA; Turan N; Slany R; Turner BM; Nightingale KP
    Epigenetics Chromatin; 2016; 9():52. PubMed ID: 27895715
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential.
    Wong SH; Goode DL; Iwasaki M; Wei MC; Kuo HP; Zhu L; Schneidawind D; Duque-Afonso J; Weng Z; Cleary ML
    Cancer Cell; 2015 Aug; 28(2):198-209. PubMed ID: 26190263
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.
    Denissov S; Hofemeister H; Marks H; Kranz A; Ciotta G; Singh S; Anastassiadis K; Stunnenberg HG; Stewart AF
    Development; 2014 Feb; 141(3):526-37. PubMed ID: 24423662
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MLL1 is required for maintenance of intestinal stem cells.
    Goveas N; Waskow C; Arndt K; Heuberger J; Zhang Q; Alexopoulou D; Dahl A; Birchmeier W; Anastassiadis K; Stewart AF; Kranz A
    PLoS Genet; 2021 Dec; 17(12):e1009250. PubMed ID: 34860830
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Histone Methyltransferase MLL1 Directs Macrophage-Mediated Inflammation in Wound Healing and Is Altered in a Murine Model of Obesity and Type 2 Diabetes.
    Kimball AS; Joshi A; Carson WF; Boniakowski AE; Schaller M; Allen R; Bermick J; Davis FM; Henke PK; Burant CF; Kunkel SL; Gallagher KA
    Diabetes; 2017 Sep; 66(9):2459-2471. PubMed ID: 28663191
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MLL1/WDR5 complex in leukemogenesis and epigenetic regulation.
    Wu M; Shu HB
    Chin J Cancer; 2011 Apr; 30(4):240-6. PubMed ID: 21439245
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High-affinity small molecular blockers of mixed lineage leukemia 1 (MLL1)-WDR5 interaction inhibit MLL1 complex H3K4 methyltransferase activity.
    Li DD; Chen WL; Wang ZH; Xie YY; Xu XL; Jiang ZY; Zhang XJ; You QD; Guo XK
    Eur J Med Chem; 2016 Nov; 124():480-489. PubMed ID: 27598236
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB.
    Wang X; Zhu K; Li S; Liao Y; Du R; Zhang X; Shu HB; Guo AY; Li L; Wu M
    J Cell Sci; 2012 Sep; 125(Pt 17):4058-66. PubMed ID: 22623725
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.