BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 30628724)

  • 1. Polycomb group proteins EZH2 and EED directly regulate androgen receptor in advanced prostate cancer.
    Liu Q; Wang G; Li Q; Jiang W; Kim JS; Wang R; Zhu S; Wang X; Yan L; Yi Y; Zhang L; Meng Q; Li C; Zhao D; Qiao Y; Li Y; Gursel DB; Chinnaiyan AM; Chen K; Cao Q
    Int J Cancer; 2019 Jul; 145(2):415-426. PubMed ID: 30628724
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator.
    Kim J; Lee Y; Lu X; Song B; Fong KW; Cao Q; Licht JD; Zhao JC; Yu J
    Cell Rep; 2018 Dec; 25(10):2808-2820.e4. PubMed ID: 30517868
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer.
    Takayama K; Suzuki T; Tsutsumi S; Fujimura T; Urano T; Takahashi S; Homma Y; Aburatani H; Inoue S
    Oncotarget; 2015 Feb; 6(4):2263-76. PubMed ID: 25537508
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacological inhibition of noncanonical EED-EZH2 signaling overcomes chemoresistance in prostate cancer.
    Li X; Gera L; Zhang S; Chen Y; Lou L; Wilson LM; Xie ZR; Sautto G; Liu D; Danaher A; Mamouni K; Yang Y; Du Y; Fu H; Kucuk O; Osunkoya AO; Zhou J; Wu D
    Theranostics; 2021; 11(14):6873-6890. PubMed ID: 34093859
    [No Abstract]   [Full Text] [Related]  

  • 5. Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction.
    Du D; Xu D; Zhu L; Stazi G; Zwergel C; Liu Y; Luo Z; Li Y; Zhang Y; Zhu K; Ding Y; Liu J; Fan S; Zhao K; Zhang N; Kong X; Jiang H; Chen K; Zhao K; Valente S; Min J; Duan W; Luo C
    J Med Chem; 2021 Jun; 64(12):8194-8207. PubMed ID: 34077206
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A cryptic transactivation domain of EZH2 binds AR and AR's splice variant, promoting oncogene activation and tumorous transformation.
    Wang J; Park KS; Yu X; Gong W; Earp HS; Wang GG; Jin J; Cai L
    Nucleic Acids Res; 2022 Oct; 50(19):10929-10946. PubMed ID: 36300627
    [TBL] [Abstract][Full Text] [Related]  

  • 7. EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.
    Xu K; Wu ZJ; Groner AC; He HH; Cai C; Lis RT; Wu X; Stack EC; Loda M; Liu T; Xu H; Cato L; Thornton JE; Gregory RI; Morrissey C; Vessella RL; Montironi R; Magi-Galluzzi C; Kantoff PW; Balk SP; Liu XS; Brown M
    Science; 2012 Dec; 338(6113):1465-9. PubMed ID: 23239736
    [TBL] [Abstract][Full Text] [Related]  

  • 8. miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src.
    Shi XB; Ma AH; Xue L; Li M; Nguyen HG; Yang JC; Tepper CG; Gandour-Edwards R; Evans CP; Kung HJ; deVere White RW
    Cancer Res; 2015 Dec; 75(24):5309-17. PubMed ID: 26573802
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Androgens suppress EZH2 expression via retinoblastoma (RB) and p130-dependent pathways: a potential mechanism of androgen-refractory progression of prostate cancer.
    Bohrer LR; Chen S; Hallstrom TC; Huang H
    Endocrinology; 2010 Nov; 151(11):5136-45. PubMed ID: 20881251
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.
    Kong X; Chen L; Jiao L; Jiang X; Lian F; Lu J; Zhu K; Du D; Liu J; Ding H; Zhang N; Shen J; Zheng M; Chen K; Liu X; Jiang H; Luo C
    J Med Chem; 2014 Nov; 57(22):9512-21. PubMed ID: 25369470
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ubiquitous expressed transcript promotes tumorigenesis by acting as a positive modulator of the polycomb repressive complex 2 in clear cell renal cell carcinoma.
    Zeng J; Xiang W; Zhang Y; Huang C; Chen K; Chen Z
    BMC Cancer; 2019 Sep; 19(1):874. PubMed ID: 31481081
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Collaboration of Kras and androgen receptor signaling stimulates EZH2 expression and tumor-propagating cells in prostate cancer.
    Cai H; Memarzadeh S; Stoyanova T; Beharry Z; Kraft AS; Witte ON
    Cancer Res; 2012 Sep; 72(18):4672-81. PubMed ID: 22805308
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta.
    Cao P; Deng Z; Wan M; Huang W; Cramer SD; Xu J; Lei M; Sui G
    Mol Cancer; 2010 May; 9():108. PubMed ID: 20478051
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BRCA1 and EZH2 cooperate in regulation of prostate cancer stem cell phenotype.
    Gorodetska I; Lukiyanchuk V; Peitzsch C; Kozeretska I; Dubrovska A
    Int J Cancer; 2019 Dec; 145(11):2974-2985. PubMed ID: 30968962
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of EZH2 Enhances the Antitumor Efficacy of Metformin in Prostate Cancer.
    Kong Y; Zhang Y; Mao F; Zhang Z; Li Z; Wang R; Liu J; Liu X
    Mol Cancer Ther; 2020 Dec; 19(12):2490-2501. PubMed ID: 33024029
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cooperation between Polycomb and androgen receptor during oncogenic transformation.
    Zhao JC; Yu J; Runkle C; Wu L; Hu M; Wu D; Liu JS; Wang Q; Qin ZS; Yu J
    Genome Res; 2012 Feb; 22(2):322-31. PubMed ID: 22179855
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Emodin succinyl ester inhibits malignant proliferation and migration of hepatocellular carcinoma by suppressing the interaction of AR and EZH2.
    Khan H; Jia W; Yu Z; Zaib T; Feng J; Jiang Y; Song H; Bai Y; Yang B; Feng H
    Biomed Pharmacother; 2020 Aug; 128():110244. PubMed ID: 32464306
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex.
    Duan Z; Zou JX; Yang P; Wang Y; Borowsky AD; Gao AC; Chen HW
    Prostate; 2013 Apr; 73(5):455-66. PubMed ID: 23038103
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
    Palomera-Sanchez Z; Watson GW; Wong CP; Beaver LM; Williams DE; Dashwood RH; Ho E
    J Nutr Biochem; 2017 Sep; 47():113-119. PubMed ID: 28582660
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ASC-J9(®), and not Casodex or Enzalutamide, suppresses prostate cancer stem/progenitor cell invasion via altering the EZH2-STAT3 signals.
    Wen S; Tian J; Niu Y; Li L; Yeh S; Chang C
    Cancer Lett; 2016 Jul; 376(2):377-86. PubMed ID: 27045473
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.