BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 30635357)

  • 1. Heterozygous
    Brenner D; Sieverding K; Bruno C; Lüningschrör P; Buck E; Mungwa S; Fischer L; Brockmann SJ; Ulmer J; Bliederhäuser C; Philibert CE; Satoh T; Akira S; Boillée S; Mayer B; Sendtner M; Ludolph AC; Danzer KM; Lobsiger CS; Freischmidt A; Weishaupt JH
    J Exp Med; 2019 Feb; 216(2):267-278. PubMed ID: 30635357
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice.
    Gerbino V; Kaunga E; Ye J; Canzio D; O'Keeffe S; Rudnick ND; Guarnieri P; Lutz CM; Maniatis T
    Neuron; 2020 Jun; 106(5):789-805.e5. PubMed ID: 32220666
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice.
    Duan W; Guo M; Yi L; Zhang J; Bi Y; Liu Y; Li Y; Li Z; Ma Y; Zhang G; Liu Y; Song X; Li C
    Aging (Albany NY); 2019 Apr; 11(8):2457-2476. PubMed ID: 31039129
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.
    Beers DR; Henkel JS; Xiao Q; Zhao W; Wang J; Yen AA; Siklos L; McKercher SR; Appel SH
    Proc Natl Acad Sci U S A; 2006 Oct; 103(43):16021-6. PubMed ID: 17043238
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct roles for motor neuron autophagy early and late in the SOD1
    Rudnick ND; Griffey CJ; Guarnieri P; Gerbino V; Wang X; Piersaint JA; Tapia JC; Rich MM; Maniatis T
    Proc Natl Acad Sci U S A; 2017 Sep; 114(39):E8294-E8303. PubMed ID: 28904095
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Milanese M; Giribaldi F; Melone M; Bonifacino T; Musante I; Carminati E; Rossi PI; Vergani L; Voci A; Conti F; Puliti A; Bonanno G
    Neurobiol Dis; 2014 Apr; 64():48-59. PubMed ID: 24361555
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43
    Sieverding K; Ulmer J; Bruno C; Satoh T; Tsao W; Freischmidt A; Akira S; Wong PC; Ludolph AC; Danzer KM; Lobsiger CS; Brenner D; Weishaupt JH
    Exp Neurol; 2021 Jan; 335():113496. PubMed ID: 33038415
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ablation of P2X7 receptor exacerbates gliosis and motoneuron death in the SOD1-G93A mouse model of amyotrophic lateral sclerosis.
    Apolloni S; Amadio S; Montilli C; Volonté C; D'Ambrosi N
    Hum Mol Genet; 2013 Oct; 22(20):4102-16. PubMed ID: 23736299
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).
    Crippa V; Sau D; Rusmini P; Boncoraglio A; Onesto E; Bolzoni E; Galbiati M; Fontana E; Marino M; Carra S; Bendotti C; De Biasi S; Poletti A
    Hum Mol Genet; 2010 Sep; 19(17):3440-56. PubMed ID: 20570967
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Influence of methylene blue on microglia-induced inflammation and motor neuron degeneration in the SOD1(G93A) model for ALS.
    Dibaj P; Zschüntzsch J; Steffens H; Scheffel J; Göricke B; Weishaupt JH; Le Meur K; Kirchhoff F; Hanisch UK; Schomburg ED; Neusch C
    PLoS One; 2012; 7(8):e43963. PubMed ID: 22952827
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1
    MacLean M; Juranek J; Cuddapah S; López-Díez R; Ruiz HH; Hu J; Frye L; Li H; Gugger PF; Schmidt AM
    J Neuroinflammation; 2021 Jun; 18(1):139. PubMed ID: 34130712
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterizing the multiple roles of FGF-2 in SOD1
    Kefalakes E; Böselt S; Sarikidi A; Ettcheto M; Bursch F; Naujock M; Stanslowsky N; Schmuck M; Barenys M; Wegner F; Grothe C; Petri S
    J Cell Physiol; 2019 May; 234(5):7395-7410. PubMed ID: 30370540
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Ringer C; Büning LS; Schäfer MK; Eiden LE; Weihe E; Schütz B
    Neurobiol Dis; 2013 Jun; 54():32-42. PubMed ID: 23466699
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Myeloid TBK1 Deficiency Induces Motor Deficits and Axon Degeneration Through Inflammatory Cell Infiltration.
    Duan W; Yi L; Tian Y; Huang HP; Li Z; Bi Y; Guo M; Li Y; Liu Y; Ma Y; Song X; Liu Y; Li C
    Mol Neurobiol; 2021 May; 58(5):2435-2446. PubMed ID: 33439438
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
    Hadano S; Mitsui S; Pan L; Otomo A; Kubo M; Sato K; Ono S; Onodera W; Abe K; Chen X; Koike M; Uchiyama Y; Aoki M; Warabi E; Yamamoto M; Ishii T; Yanagawa T; Shang HF; Yoshii F
    Hum Mol Genet; 2016 Aug; 25(15):3321-3340. PubMed ID: 27439389
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In-vivo genetic ablation of metabotropic glutamate receptor type 5 slows down disease progression in the SOD1
    Bonifacino T; Provenzano F; Gallia E; Ravera S; Torazza C; Bossi S; Ferrando S; Puliti A; Van Den Bosch L; Bonanno G; Milanese M
    Neurobiol Dis; 2019 Sep; 129():79-92. PubMed ID: 31102766
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression.
    Apolloni S; Fabbrizio P; Amadio S; Volonté C
    J Neuroinflammation; 2016 Aug; 13(1):191. PubMed ID: 27549088
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tweak regulates astrogliosis, microgliosis and skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis.
    Bowerman M; Salsac C; Coque E; Eiselt É; Deschaumes RG; Brodovitch A; Burkly LC; Scamps F; Raoul C
    Hum Mol Genet; 2015 Jun; 24(12):3440-56. PubMed ID: 25765661
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In-vivo effects of knocking-down metabotropic glutamate receptor 5 in the SOD1
    Bonifacino T; Cattaneo L; Gallia E; Puliti A; Melone M; Provenzano F; Bossi S; Musante I; Usai C; Conti F; Bonanno G; Milanese M
    Neuropharmacology; 2017 Sep; 123():433-445. PubMed ID: 28645622
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.