BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 30638966)

  • 1. Design, synthesis and identification of novel coumaperine derivatives for inhibition of human 5-LOX: Antioxidant, pseudoperoxidase and docking studies.
    Muthuraman S; Sinha S; Vasavi CS; Waidha KM; Basu B; Munussami P; Balamurali MM; Doble M; Saravana Kumar R
    Bioorg Med Chem; 2019 Feb; 27(4):604-619. PubMed ID: 30638966
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase.
    Sinha S; Doble M; Manju SL
    Eur J Med Chem; 2018 Oct; 158():34-50. PubMed ID: 30199704
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, biological evaluation and docking studies of new 3-(4,5-dihydro-1H-pyrazol/isoxazol-5-yl)-2-phenyl-1H-indole derivatives as potent antioxidants and 15-lipoxygenase inhibitors.
    ElBordiny HS; El-Miligy MM; Kassab SE; Daabees H; Mohamed Ali WA; Abdelhamid Mohamed El-Hawash S
    Eur J Med Chem; 2018 Feb; 145():594-605. PubMed ID: 29339254
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A rat air pouch model for evaluating the efficacy and selectivity of 5-lipoxygenase inhibitors.
    Zweifel BS; Hardy MM; Anderson GD; Dufield DR; Pufahl RA; Masferrer JL
    Eur J Pharmacol; 2008 Apr; 584(1):166-74. PubMed ID: 18295198
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluation of novel 1,2-diaryl-4-substituted-benzylidene-5(4H)-imidazolone derivatives as cytotoxic agents and COX-2/LOX inhibitors.
    Lamie PF; Philoppes JN; Rárová L
    Arch Pharm (Weinheim); 2018 Apr; 351(3-4):e1700311. PubMed ID: 29400411
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives.
    Srivastava P; Vyas VK; Variya B; Patel P; Qureshi G; Ghate M
    Bioorg Chem; 2016 Aug; 67():130-8. PubMed ID: 27376460
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
    El-Nagar MKS; Abdu-Allah HHM; Salem OIA; Kafafy AN; Farghaly HSM
    Bioorg Chem; 2018 Aug; 78():80-93. PubMed ID: 29550533
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of novel hybrids of pyrazole and coumarin as dual inhibitors of COX-2 and 5-LOX.
    Shen FQ; Wang ZC; Wu SY; Ren SZ; Man RJ; Wang BZ; Zhu HL
    Bioorg Med Chem Lett; 2017 Aug; 27(16):3653-3660. PubMed ID: 28720504
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pyrazole Derivatives of Medically Relevant Phenolic Acids: Insight into Antioxidative and Anti-LOX Activity.
    Milovanović V; Petrović ZD; Novaković S; Bogdanović GA; Simijonović D; Mladenović M; Branković J; Petrović VP
    Med Chem; 2021; 17(8):807-819. PubMed ID: 32484771
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA; Labib MB; Abdel-Latif M
    Bioorg Chem; 2017 Oct; 74():212-220. PubMed ID: 28865292
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors.
    Ali SA; Awad SM; Said AM; Mahgoub S; Taha H; Ahmed NM
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):847-863. PubMed ID: 32216479
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, in vitro and in silico evaluation of diaryl heptanones as potential 5LOX enzyme inhibitors.
    Meka B; Ravada SR; Muthyala MKK; Kurre PN; Golakoti T
    Bioorg Chem; 2018 Oct; 80():408-421. PubMed ID: 29986187
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of NSAIDs as lipoxygenase inhibitors through highly sensitive chemiluminescence method, expression analysis in mononuclear cells and computational studies.
    Shahid W; Ejaz SA; Al-Rashida M; Saleem M; Ahmed M; Rahman J; Riaz N; Ashraf M
    Bioorg Chem; 2021 May; 110():104818. PubMed ID: 33784531
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core.
    Sisa M; Dvorakova M; Temml V; Jarosova V; Vanek T; Landa P
    Eur J Med Chem; 2020 Oct; 204():112620. PubMed ID: 32738413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX-2/5-LOX inhibitors.
    Shaaban MA; Kamal AM; Faggal SI; Farag NA; Aborehab NM; Elsahar AE; Mohamed KO
    Arch Pharm (Weinheim); 2020 Nov; 353(11):e2000027. PubMed ID: 32696514
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, anti-inflammatory screening, molecular docking, and COX-1,2/-5-LOX inhibition profile of some novel quinoline derivatives.
    Chaaban I; Rizk OH; Ibrahim TM; Henen SS; El-Khawass EM; Bayad AE; El-Ashmawy IM; Nematalla HA
    Bioorg Chem; 2018 Aug; 78():220-235. PubMed ID: 29602046
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study.
    Lamie PF; Ali WAM; Bazgier V; Rárová L
    Eur J Med Chem; 2016 Nov; 123():803-813. PubMed ID: 27541263
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, biological evaluation and docking study of novel indole-2-amide as anti-inflammatory agents with dual inhibition of COX and 5-LOX.
    Huang Y; Zhang B; Li J; Liu H; Zhang Y; Yang Z; Liu W
    Eur J Med Chem; 2019 Oct; 180():41-50. PubMed ID: 31299586
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular hybrids of substituted phenylcarbamoylpiperidine and 1,2,4-triazole methylacetamide as potent 15-LOX inhibitors: Design, synthesis, DFT calculations and molecular docking studies.
    Nawaz Z; Riaz N; Saleem M; Iqbal A; Abida Ejaz S; Bashir B; Muzaffar S; Ashraf M; Aziz-Ur-Rehman ; Sajjad Bilal M; Krishna Prabhala B; Sajid S
    Bioorg Chem; 2024 Feb; 143():106984. PubMed ID: 38056389
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of purine-pyrazole hybrids incorporating thiazole, thiazolidinone or rhodanine moiety as 15-LOX inhibitors endowed with anticancer and antioxidant potential.
    Afifi OS; Shaaban OG; Abd El Razik HA; Shams El-Dine SEA; Ashour FA; El-Tombary AA; Abu-Serie MM
    Bioorg Chem; 2019 Jun; 87():821-837. PubMed ID: 30999135
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.