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2. Combination of TMB and CNA Stratifies Prognostic and Predictive Responses to Immunotherapy Across Metastatic Cancer. Liu L; Bai X; Wang J; Tang XR; Wu DH; Du SS; Du XJ; Zhang YW; Zhu HB; Fang Y; Guo ZQ; Zeng Q; Guo XJ; Liu Z; Dong ZY Clin Cancer Res; 2019 Dec; 25(24):7413-7423. PubMed ID: 31515453 [TBL] [Abstract][Full Text] [Related]
3. Pan-cancer Analysis of Tumor Mutational Burden and Homologous Recombination DNA Damage Repair Using Targeted Next-Generation Sequencing. Wang HY; Deng L; Li YQ; Zhang X; Long YK; Zhang X; Feng YF; He Y; Tang T; Yang XH; Wang F Cancer Res Treat; 2021 Oct; 53(4):973-982. PubMed ID: 33677848 [TBL] [Abstract][Full Text] [Related]
4. A mutation-based gene set predicts survival benefit after immunotherapy across multiple cancers and reveals the immune response landscape. Long J; Wang D; Wang A; Chen P; Lin Y; Bian J; Yang X; Zheng M; Zhang H; Zheng Y; Sang X; Zhao H Genome Med; 2022 Feb; 14(1):20. PubMed ID: 35197093 [TBL] [Abstract][Full Text] [Related]
5. The interplay between cancer type, panel size and tumor mutational burden threshold in patient selection for cancer immunotherapy. Golkaram M; Zhao C; Kruglyak K; Zhang S; Bilke S PLoS Comput Biol; 2020 Nov; 16(11):e1008332. PubMed ID: 33166276 [TBL] [Abstract][Full Text] [Related]
6. Assessment of Tumor Mutational Burden and Outcomes in Patients With Diverse Advanced Cancers Treated With Immunotherapy. Aggarwal C; Ben-Shachar R; Gao Y; Hyun SW; Rivers Z; Epstein C; Kaneva K; Sangli C; Nimeiri H; Patel J JAMA Netw Open; 2023 May; 6(5):e2311181. PubMed ID: 37129893 [TBL] [Abstract][Full Text] [Related]
7. Tumor mutational burden assessed by targeted NGS predicts clinical benefit from immune checkpoint inhibitors in non-small cell lung cancer. Alborelli I; Leonards K; Rothschild SI; Leuenberger LP; Savic Prince S; Mertz KD; Poechtrager S; Buess M; Zippelius A; Läubli H; Haegele J; Tolnay M; Bubendorf L; Quagliata L; Jermann P J Pathol; 2020 Jan; 250(1):19-29. PubMed ID: 31471895 [TBL] [Abstract][Full Text] [Related]
8. Impact of high tumor mutational burden in solid tumors and challenges for biomarker application. McNamara MG; Jacobs T; Lamarca A; Hubner RA; Valle JW; Amir E Cancer Treat Rev; 2020 Sep; 89():102084. PubMed ID: 32738738 [TBL] [Abstract][Full Text] [Related]
9. Clinical advantage of targeted sequencing for unbiased tumor mutational burden estimation in samples with low tumor purity. Hong TH; Cha H; Shim JH; Lee B; Chung J; Lee C; Kim NKD; Choi YL; Hwang S; Lee Y; Park S; Jung HA; Kim JY; Park YH; Sun JM; Ahn JS; Ahn MJ; Park K; Lee SH; Park WY J Immunother Cancer; 2020 Oct; 8(2):. PubMed ID: 33077514 [TBL] [Abstract][Full Text] [Related]
10. Tumor mutational burden as a predictive biomarker for checkpoint inhibitor immunotherapy. Lee M; Samstein RM; Valero C; Chan TA; Morris LGT Hum Vaccin Immunother; 2020; 16(1):112-115. PubMed ID: 31361563 [TBL] [Abstract][Full Text] [Related]
11. Response Rates to Anti-PD-1 Immunotherapy in Microsatellite-Stable Solid Tumors With 10 or More Mutations per Megabase. Valero C; Lee M; Hoen D; Zehir A; Berger MF; Seshan VE; Chan TA; Morris LGT JAMA Oncol; 2021 May; 7(5):739-743. PubMed ID: 33599686 [TBL] [Abstract][Full Text] [Related]
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13. Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer. Ricciuti B; Kravets S; Dahlberg SE; Umeton R; Albayrak A; Subegdjo SJ; Johnson BE; Nishino M; Sholl LM; Awad MM J Immunother Cancer; 2019 Mar; 7(1):87. PubMed ID: 30922388 [TBL] [Abstract][Full Text] [Related]
14. Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real-life analysis of three larger gene panels. Endris V; Buchhalter I; Allgäuer M; Rempel E; Lier A; Volckmar AL; Kirchner M; von Winterfeld M; Leichsenring J; Neumann O; Penzel R; Weichert W; Glimm H; Fröhling S; Winter H; Herth F; Thomas M; Schirmacher P; Budczies J; Stenzinger A Int J Cancer; 2019 May; 144(9):2303-2312. PubMed ID: 30446996 [TBL] [Abstract][Full Text] [Related]
15. Applicability of Routine Targeted Next-generation Sequencing to Estimate Tumor Mutational Burden (TMB) in Patients Treated With Immune Checkpoint Inhibitor Therapy. Pinato DJ; Urus H; Newsom-Davis T; Du Parcq P; Belessiotis K; Mapara L; Gupta N; Power D; Weir J; Wong CN; Ratnakumaran RP; Dominy K; Khorashad J; Bower M J Immunother; 2020; 43(2):53-56. PubMed ID: 31567705 [TBL] [Abstract][Full Text] [Related]
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18. Tumor mutational burden standardization initiatives: Recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy treatment decisions. Stenzinger A; Allen JD; Maas J; Stewart MD; Merino DM; Wempe MM; Dietel M Genes Chromosomes Cancer; 2019 Aug; 58(8):578-588. PubMed ID: 30664300 [TBL] [Abstract][Full Text] [Related]
19. Novel tumor mutation score versus tumor mutation burden in predicting survival after immunotherapy in pan-cancer patients from the MSK-IMPACT cohort. Li Y; Chen Z; Wu L; Tao W Ann Transl Med; 2020 Apr; 8(7):446. PubMed ID: 32395490 [TBL] [Abstract][Full Text] [Related]
20. The association between tumor mutational burden and prognosis is dependent on treatment context. Valero C; Lee M; Hoen D; Wang J; Nadeem Z; Patel N; Postow MA; Shoushtari AN; Plitas G; Balachandran VP; Smith JJ; Crago AM; Long Roche KC; Kelly DW; Samstein RM; Rana S; Ganly I; Wong RJ; Hakimi AA; Berger MF; Zehir A; Solit DB; Ladanyi M; Riaz N; Chan TA; Seshan VE; Morris LGT Nat Genet; 2021 Jan; 53(1):11-15. PubMed ID: 33398197 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]