BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 30649895)

  • 1. Alveolar Macrophage Apoptosis-associated Bacterial Killing Helps Prevent Murine Pneumonia.
    Preston JA; Bewley MA; Marriott HM; McGarry Houghton A; Mohasin M; Jubrail J; Morris L; Stephenson YL; Cross S; Greaves DR; Craig RW; van Rooijen N; Bingle CD; Read RC; Mitchell TJ; Whyte MKB; Shapiro SD; Dockrell DH
    Am J Respir Crit Care Med; 2019 Jul; 200(1):84-97. PubMed ID: 30649895
    [No Abstract]   [Full Text] [Related]  

  • 2. Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages.
    Bewley MA; Preston JA; Mohasin M; Marriott HM; Budd RC; Swales J; Collini P; Greaves DR; Craig RW; Brightling CE; Donnelly LE; Barnes PJ; Singh D; Shapiro SD; Whyte MKB; Dockrell DH
    Am J Respir Crit Care Med; 2017 Oct; 196(7):845-855. PubMed ID: 28557543
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alveolar macrophages in pulmonary host defence the unrecognized role of apoptosis as a mechanism of intracellular bacterial killing.
    Aberdein JD; Cole J; Bewley MA; Marriott HM; Dockrell DH
    Clin Exp Immunol; 2013 Nov; 174(2):193-202. PubMed ID: 23841514
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance.
    Marriott HM; Bingle CD; Read RC; Braley KE; Kroemer G; Hellewell PG; Craig RW; Whyte MK; Dockrell DH
    J Clin Invest; 2005 Feb; 115(2):359-68. PubMed ID: 15650769
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells.
    Pandey MK; Gowda K; Doi K; Sharma AK; Wang HG; Amin S
    PLoS One; 2013; 8(11):e78570. PubMed ID: 24223823
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of Mcl-1 with the pan-Bcl-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia.
    Pan R; Ruvolo VR; Wei J; Konopleva M; Reed JC; Pellecchia M; Andreeff M; Ruvolo PP
    Blood; 2015 Jul; 126(3):363-72. PubMed ID: 26045609
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The ratio of Mcl-1 and Noxa determines ABT737 resistance in squamous cell carcinoma of the skin.
    Geserick P; Wang J; Feoktistova M; Leverkus M
    Cell Death Dis; 2014 Sep; 5(9):e1412. PubMed ID: 25210795
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Decreased alveolar macrophage apoptosis is associated with increased pulmonary inflammation in a murine model of pneumococcal pneumonia.
    Marriott HM; Hellewell PG; Cross SS; Ince PG; Whyte MK; Dockrell DH
    J Immunol; 2006 Nov; 177(9):6480-8. PubMed ID: 17056580
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex.
    Konopleva M; Milella M; Ruvolo P; Watts JC; Ricciardi MR; Korchin B; McQueen T; Bornmann W; Tsao T; Bergamo P; Mak DH; Chen W; McCubrey J; Tafuri A; Andreeff M
    Leukemia; 2012 Apr; 26(4):778-87. PubMed ID: 22064351
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pneumolysin activates macrophage lysosomal membrane permeabilization and executes apoptosis by distinct mechanisms without membrane pore formation.
    Bewley MA; Naughton M; Preston J; Mitchell A; Holmes A; Marriott HM; Read RC; Mitchell TJ; Whyte MK; Dockrell DH
    mBio; 2014 Oct; 5(5):e01710-14. PubMed ID: 25293758
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phagocytosis and killing of common bacterial pathogens of the lung by human alveolar macrophages.
    Jonsson S; Musher DM; Chapman A; Goree A; Lawrence EC
    J Infect Dis; 1985 Jul; 152(1):4-13. PubMed ID: 3874252
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages.
    Jubrail J; Morris P; Bewley MA; Stoneham S; Johnston SA; Foster SJ; Peden AA; Read RC; Marriott HM; Dockrell DH
    Cell Microbiol; 2016 Jan; 18(1):80-96. PubMed ID: 26248337
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased lethality and defective pulmonary clearance of Streptococcus pneumoniae in microsomal prostaglandin E synthase-1-knockout mice.
    Dolan JM; Weinberg JB; O'Brien E; Abashian A; Procario MC; Aronoff DM; Crofford LJ; Peters-Golden M; Ward L; Mancuso P
    Am J Physiol Lung Cell Mol Physiol; 2016 Jun; 310(11):L1111-20. PubMed ID: 27059285
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitochondrial Reactive Oxygen Species Enhance Alveolar Macrophage Activity against Aspergillus fumigatus but Are Dispensable for Host Protection.
    Shlezinger N; Hohl TM
    mSphere; 2021 Jun; 6(3):e0026021. PubMed ID: 34077261
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages.
    Belchamber KBR; Singh R; Batista CM; Whyte MK; Dockrell DH; Kilty I; Robinson MJ; Wedzicha JA; Barnes PJ; Donnelly LE;
    Eur Respir J; 2019 Oct; 54(4):. PubMed ID: 31320451
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung.
    Lucas CD; Dorward DA; Tait MA; Fox S; Marwick JA; Allen KC; Robb CT; Hirani N; Haslett C; Duffin R; Rossi AG
    Mucosal Immunol; 2014 Jul; 7(4):857-68. PubMed ID: 24280938
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease Is Enhanced by Nrf2 Agonists.
    Bewley MA; Budd RC; Ryan E; Cole J; Collini P; Marshall J; Kolsum U; Beech G; Emes RD; Tcherniaeva I; Berbers GAM; Walmsley SR; Donaldson G; Wedzicha JA; Kilty I; Rumsey W; Sanchez Y; Brightling CE; Donnelly LE; Barnes PJ; Singh D; Whyte MKB; Dockrell DH;
    Am J Respir Crit Care Med; 2018 Sep; 198(6):739-750. PubMed ID: 29547002
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Staphylococcus aureus Uses the GraXRS Regulatory System To Sense and Adapt to the Acidified Phagolysosome in Macrophages.
    Flannagan RS; Kuiack RC; McGavin MJ; Heinrichs DE
    mBio; 2018 Jul; 9(4):. PubMed ID: 30018109
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HIV gp120 in the Lungs of Antiretroviral Therapy-treated Individuals Impairs Alveolar Macrophage Responses to Pneumococci.
    Collini PJ; Bewley MA; Mohasin M; Marriott HM; Miller RF; Geretti AM; Beloukas A; Papadimitropoulos A; Read RC; Noursadeghi M; Dockrell DH
    Am J Respir Crit Care Med; 2018 Jun; 197(12):1604-1615. PubMed ID: 29365279
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer.
    Nakajima W; Hicks MA; Tanaka N; Krystal GW; Harada H
    Cell Death Dis; 2014 Feb; 5(2):e1052. PubMed ID: 24525728
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.