BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

399 related articles for article (PubMed ID: 30657049)

  • 1. Synthesis of Oridonin Derivatives via Mizoroki-Heck Reaction and Click Chemistry for Cytotoxic Activity.
    Hou W; Fan Q; Su L; Xu H
    Anticancer Agents Med Chem; 2019; 19(7):935-947. PubMed ID: 30657049
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel anticancer oridonin derivatives possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: Design, synthesis, biological evaluation and nitric oxide release studies.
    Xu S; Wang G; Lin Y; Zhang Y; Pei L; Yao H; Hu M; Qiu Y; Huang Z; Zhang Y; Xu J
    Bioorg Med Chem Lett; 2016 Jun; 26(12):2795-2800. PubMed ID: 27158140
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of novel oridonin analogues as potent anticancer agents.
    Shen QK; Chen ZA; Zhang HJ; Li JL; Liu CF; Gong GH; Quan ZS
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):324-333. PubMed ID: 29303372
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The conversion of oridonin to spirolactone-type or enmein-type diterpenoid: synthesis and biological evaluation of ent-6,7-seco-oridonin derivatives as novel potential anticancer agents.
    Wang L; Li D; Xu S; Cai H; Yao H; Zhang Y; Jiang J; Xu J
    Eur J Med Chem; 2012 Jun; 52():242-50. PubMed ID: 22483090
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Probing the Anticancer Action of Oridonin with Fluorescent Analogues: Visualizing Subcellular Localization to Mitochondria.
    Xu S; Luo S; Yao H; Cai H; Miao X; Wu F; Yang DH; Wu X; Xie W; Yao H; Chen ZS; Xu J
    J Med Chem; 2016 May; 59(10):5022-34. PubMed ID: 27089099
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oridonin derivatives as potential anticancer drug candidates triggering apoptosis through mitochondrial pathway in the liver cancer cells.
    Luo D; Yi Y; Peng K; Liu T; Yang J; Liu S; Zhao W; Qu X; Yu W; Gu Y; Wan S
    Eur J Med Chem; 2019 Sep; 178():365-379. PubMed ID: 31200238
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hydrogen sulfide donating ent-kaurane and spirolactone-type 6,7-seco-ent-kaurane derivatives: Design, synthesis and antiproliferative properties.
    Li H; Gao X; Huang X; Wang X; Xu S; Uchita T; Gao M; Xu J; Hua H; Li D
    Eur J Med Chem; 2019 Sep; 178():446-457. PubMed ID: 31202992
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, and evaluation of in vitro and in vivo anticancer activity of 14-substituted oridonin analogs: A novel and potent cell cycle arrest and apoptosis inducer through the p53-MDM2 pathway.
    Shen QK; Deng H; Wang SB; Tian YS; Quan ZS
    Eur J Med Chem; 2019 Jul; 173():15-31. PubMed ID: 30981113
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enmein-type diterpenoid analogs from natural kaurene-type oridonin: Synthesis and their antitumor biological evaluation.
    Li D; Xu S; Cai H; Pei L; Zhang H; Wang L; Yao H; Wu X; Jiang J; Sun Y; Xu J
    Eur J Med Chem; 2013 Jun; 64():215-21. PubMed ID: 23644204
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of new potent anticancer derivatives through simplifying the core structure and modification on their 14- hydroxyl group from oridonin.
    Liu J; Xie S; Shao X; Xue S; Du P; Wu H; Xu S; Chen ZS; Yang DH; Xu J; Yao H
    Eur J Med Chem; 2022 Mar; 231():114155. PubMed ID: 35121201
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and Cytotoxicity Assessment of Novel 7-O- and 14-O-Derivatives of Glaucocalyxin A.
    Liu HC; Qiao LM; Zheng W; Xiang ZB; Chen HS; Yu SC; Zhang DZ; Wang T; Zhang YF; Jin YS
    Anticancer Agents Med Chem; 2020; 20(10):1241-1249. PubMed ID: 32116205
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of novel Jiyuan Oridonin A-1,2,3-triazole-azole derivatives as antiproliferative agents.
    Ke Y; Liang JJ; Hou RJ; Li MM; Zhao LF; Wang W; Liu Y; Xie H; Yang RH; Hu TX; Wang JY; Liu HM
    Eur J Med Chem; 2018 Sep; 157():1249-1263. PubMed ID: 30193221
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway.
    Xu S; Yao H; Luo S; Zhang YK; Yang DH; Li D; Wang G; Hu M; Qiu Y; Wu X; Yao H; Xie W; Chen ZS; Xu J
    J Med Chem; 2017 Feb; 60(4):1449-1468. PubMed ID: 28165738
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effective enmein-type mimics of clinical candidate HAO472: Design, synthesis and biological evaluation.
    Hu X; Bai Z; Qiao J; Li H; Xu S; Wang X; Xu Y; Xu J; Hua H; Li D
    Eur J Med Chem; 2019 Jun; 171():169-179. PubMed ID: 30921757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel nitrogen-enriched oridonin analogues with thiazole-fused A-ring: protecting group-free synthesis, enhanced anticancer profile, and improved aqueous solubility.
    Ding C; Zhang Y; Chen H; Yang Z; Wild C; Chu L; Liu H; Shen Q; Zhou J
    J Med Chem; 2013 Jun; 56(12):5048-58. PubMed ID: 23746196
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oridonin, a Promising ent-Kaurane Diterpenoid Lead Compound.
    Li D; Han T; Liao J; Hu X; Xu S; Tian K; Gu X; Cheng K; Li Z; Hua H; Xu J
    Int J Mol Sci; 2016 Aug; 17(9):. PubMed ID: 27563888
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, Cytotoxicity and Antimicrobial Activity of New Enmein-type Kauranoid Diterpenoid Derivatives.
    Li D; Han T; Hu X; Tian K; Xu S; Zhou T; Cheng K; Li Z; Hua H; Xu J
    Anticancer Agents Med Chem; 2017; 17(12):1679-1688. PubMed ID: 28403782
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Click chemistry-based synthesis and cytotoxic activity evaluation of 4α-triazole acetate podophyllotoxin derivatives.
    Hou W; Zhang G; Luo Z; Su L; Xu H
    Chem Biol Drug Des; 2019 Apr; 93(4):473-483. PubMed ID: 30394007
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, biological evaluation and cellular localization study of fluorescent derivatives of Jiyuan Oridonin A.
    Zhou C; Zhang JY; Liu HB; Tian XY; Liu Y; Wang YL; Zheng ZJ; Wang N; Wang ZJ; Xu X; Liu HM; Ke Y
    Eur J Med Chem; 2022 Feb; 229():114048. PubMed ID: 34954589
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and anticancer evaluation of complex unsaturated isosteviol-derived triazole conjugates.
    Khaybullin RN; Liang X; Cisneros K; Qi X
    Future Med Chem; 2015; 7(18):2419-28. PubMed ID: 26653151
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.