BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

332 related articles for article (PubMed ID: 30660504)

  • 1. Therapeutic Dissolution of Aberrant Phases by Nuclear-Import Receptors.
    Guo L; Fare CM; Shorter J
    Trends Cell Biol; 2019 Apr; 29(4):308-322. PubMed ID: 30660504
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.
    Guo L; Kim HJ; Wang H; Monaghan J; Freyermuth F; Sung JC; O'Donovan K; Fare CM; Diaz Z; Singh N; Zhang ZC; Coughlin M; Sweeny EA; DeSantis ME; Jackrel ME; Rodell CB; Burdick JA; King OD; Gitler AD; Lagier-Tourenne C; Pandey UB; Chook YM; Taylor JP; Shorter J
    Cell; 2018 Apr; 173(3):677-692.e20. PubMed ID: 29677512
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nuclear-Import Receptors Counter Deleterious Phase Transitions in Neurodegenerative Disease.
    Odeh HM; Fare CM; Shorter J
    J Mol Biol; 2022 Jan; 434(1):167220. PubMed ID: 34464655
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuclear-import receptors as gatekeepers of pathological phase transitions in ALS/FTD.
    Khalil B; Linsenmeier M; Smith CL; Shorter J; Rossoll W
    Mol Neurodegener; 2024 Jan; 19(1):8. PubMed ID: 38254150
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RNA-binding proteins with prion-like domains in health and disease.
    Harrison AF; Shorter J
    Biochem J; 2017 Apr; 474(8):1417-1438. PubMed ID: 28389532
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulating Phase Transition in Neurodegenerative Diseases by Nuclear Import Receptors.
    Girdhar A; Guo L
    Biology (Basel); 2022 Jul; 11(7):. PubMed ID: 36101390
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Beyond the Transport Function of Import Receptors: What's All the FUS about?
    Mikhaleva S; Lemke EA
    Cell; 2018 Apr; 173(3):549-553. PubMed ID: 29677508
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity.
    Fare CM; Rhine K; Lam A; Myong S; Shorter J
    J Biol Chem; 2023 Feb; 299(2):102806. PubMed ID: 36529289
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hormone-Inducible Transport Reporter Assay to Study Nuclear Import Defects in Neurodegenerative Diseases.
    Hutten S; Dormann D
    Methods Mol Biol; 2022; 2502():81-90. PubMed ID: 35412232
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
    Hofweber M; Hutten S; Bourgeois B; Spreitzer E; Niedner-Boblenz A; Schifferer M; Ruepp MD; Simons M; Niessing D; Madl T; Dormann D
    Cell; 2018 Apr; 173(3):706-719.e13. PubMed ID: 29677514
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions.
    Hutten S; Usluer S; Bourgeois B; Simonetti F; Odeh HM; Fare CM; Czuppa M; Hruska-Plochan M; Hofweber M; Polymenidou M; Shorter J; Edbauer D; Madl T; Dormann D
    Cell Rep; 2020 Dec; 33(12):108538. PubMed ID: 33357437
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phase separation and pathologic transitions of RNP condensates in neurons: implications for amyotrophic lateral sclerosis, frontotemporal dementia and other neurodegenerative disorders.
    Naskar A; Nayak A; Salaikumaran MR; Vishal SS; Gopal PP
    Front Mol Neurosci; 2023; 16():1242925. PubMed ID: 37720552
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease.
    March ZM; King OD; Shorter J
    Brain Res; 2016 Sep; 1647():9-18. PubMed ID: 26996412
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RNA modulates physiological and neuropathological protein phase transitions.
    Mann JR; Donnelly CJ
    Neuron; 2021 Sep; 109(17):2663-2681. PubMed ID: 34297914
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transportin-1 and Transportin-2: protein nuclear import and beyond.
    Twyffels L; Gueydan C; Kruys V
    FEBS Lett; 2014 May; 588(10):1857-68. PubMed ID: 24780099
    [TBL] [Abstract][Full Text] [Related]  

  • 16. C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers.
    Nanaura H; Kawamukai H; Fujiwara A; Uehara T; Aiba Y; Nakanishi M; Shiota T; Hibino M; Wiriyasermkul P; Kikuchi S; Nagata R; Matsubayashi M; Shinkai Y; Niwa T; Mannen T; Morikawa N; Iguchi N; Kiriyama T; Morishima K; Inoue R; Sugiyama M; Oda T; Kodera N; Toma-Fukai S; Sato M; Taguchi H; Nagamori S; Shoji O; Ishimori K; Matsumura H; Sugie K; Saio T; Yoshizawa T; Mori E
    Nat Commun; 2021 Sep; 12(1):5301. PubMed ID: 34489423
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biology and Pathobiology of TDP-43 and Emergent Therapeutic Strategies.
    Guo L; Shorter J
    Cold Spring Harb Perspect Med; 2017 Sep; 7(9):. PubMed ID: 27920024
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The N-terminal nuclear localization sequences of liver X receptors alpha and beta bind to importin alpha and are essential for both nuclear import and transactivating functions.
    Miller A; Crumbley C; Prüfer K
    Int J Biochem Cell Biol; 2009 Apr; 41(4):834-43. PubMed ID: 18773967
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phase separation of RNA-binding proteins in physiology and disease: An introduction to the JBC Reviews thematic series.
    Shorter J
    J Biol Chem; 2019 May; 294(18):7113-7114. PubMed ID: 30948513
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains.
    Guo L; Mann JR; Mauna JC; Copley KE; Wang H; Rubien JD; Odeh HM; Lin J; Lee BL; Ganser L; Robinson E; Kim KM; Murthy AC; Paul T; Portz B; Gleixner AM; Diaz Z; Carey JL; Smirnov A; Padilla G; Lavorando E; Espy C; Shang Y; Huang EJ; Chesi A; Fawzi NL; Myong S; Donnelly CJ; Shorter J
    bioRxiv; 2023 Sep; ():. PubMed ID: 37732211
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.