216 related articles for article (PubMed ID: 30664791)
1. ALK phosphorylates SMAD4 on tyrosine to disable TGF-β tumour suppressor functions.
Zhang Q; Xiao M; Gu S; Xu Y; Liu T; Li H; Yu Y; Qin L; Zhu Y; Chen F; Wang Y; Ding C; Wu H; Ji H; Chen Z; Zu Y; Malkoski S; Li Y; Liang T; Ji J; Qin J; Xu P; Zhao B; Shen L; Lin X; Feng XH
Nat Cell Biol; 2019 Feb; 21(2):179-189. PubMed ID: 30664791
[TBL] [Abstract][Full Text] [Related]
2. ALK-mediated Tyr95 phosphorylation of Smad4 impairs its transcription activity and the tumor suppressive activity of TGF-β.
Shi Q; Chen YG
Sci China Life Sci; 2019 Mar; 62(3):431-432. PubMed ID: 30820854
[No Abstract] [Full Text] [Related]
3.
McCarthy AJ; Chetty R
J Clin Pathol; 2018 Aug; 71(8):661-664. PubMed ID: 29720405
[TBL] [Abstract][Full Text] [Related]
4. Imatinib blocks tyrosine phosphorylation of Smad4 and restores TGF-β growth-suppressive signaling in BCR-ABL1-positive leukemia.
Wang L; Gu S; Chen F; Yu Y; Cao J; Li X; Gao C; Chen Y; Yuan S; Liu X; Qin J; Zhao B; Xu P; Liang T; Tong H; Lin X; Feng XH
Signal Transduct Target Ther; 2023 Mar; 8(1):120. PubMed ID: 36959211
[TBL] [Abstract][Full Text] [Related]
5. High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition.
Klein-Scory S; Zapatka M; Eilert-Micus C; Hoppe S; Schwarz E; Schmiegel W; Hahn SA; Schwarte-Waldhoff I
BMC Cancer; 2007 Nov; 7():209. PubMed ID: 17997817
[TBL] [Abstract][Full Text] [Related]
6. MiRNA-34a reversed TGF-β-induced epithelial-mesenchymal transition via suppression of SMAD4 in NPC cells.
Huang G; Du MY; Zhu H; Zhang N; Lu ZW; Qian LX; Zhang W; Tian X; He X; Yin L
Biomed Pharmacother; 2018 Oct; 106():217-224. PubMed ID: 29960168
[TBL] [Abstract][Full Text] [Related]
7. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
Peng B; Fleming JB; Breslin T; Grau AM; Fojioka S; Abbruzzese JL; Evans DB; Ayers D; Wathen K; Wu T; Robertson KD; Chiao PJ
Clin Cancer Res; 2002 Nov; 8(11):3628-38. PubMed ID: 12429655
[TBL] [Abstract][Full Text] [Related]
8. Restoration of Smad4 in BxPC3 pancreatic cancer cells attenuates proliferation without altering angiogenesis.
Yasutome M; Gunn J; Korc M
Clin Exp Metastasis; 2005; 22(6):461-73. PubMed ID: 16320109
[TBL] [Abstract][Full Text] [Related]
9. Protein tyrosine phosphatase PTPN2 regulates TGF-β signaling through Smad4 dephosphorylation.
Shi S; Xu D; Gu S; Xu N; Xu P; Cao J; Feng XH
Am J Cancer Res; 2022; 12(12):5516-5531. PubMed ID: 36628288
[TBL] [Abstract][Full Text] [Related]
10. Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta.
Jazag A; Ijichi H; Kanai F; Imamura T; Guleng B; Ohta M; Imamura J; Tanaka Y; Tateishi K; Ikenoue T; Kawakami T; Arakawa Y; Miyagishi M; Taira K; Kawabe T; Omata M
Oncogene; 2005 Jan; 24(4):662-71. PubMed ID: 15592526
[TBL] [Abstract][Full Text] [Related]
11. Smad4 Decreases the Population of Pancreatic Cancer-Initiating Cells through Transcriptional Repression of ALDH1A1.
Hoshino Y; Nishida J; Katsuno Y; Koinuma D; Aoki T; Kokudo N; Miyazono K; Ehata S
Am J Pathol; 2015 May; 185(5):1457-70. PubMed ID: 25769430
[TBL] [Abstract][Full Text] [Related]
12. Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells.
Chen WB; Lenschow W; Tiede K; Fischer JW; Kalthoff H; Ungefroren H
J Biol Chem; 2002 Sep; 277(39):36118-28. PubMed ID: 12140283
[TBL] [Abstract][Full Text] [Related]
13. MicroRNA-539 functions as a tumour suppressor in prostate cancer via the TGF-β/Smad4 signalling pathway by down-regulating DLX1.
Sun B; Fan Y; Yang A; Liang L; Cao J
J Cell Mol Med; 2019 Sep; 23(9):5934-5948. PubMed ID: 31298493
[TBL] [Abstract][Full Text] [Related]
14. The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells.
Deckers M; van Dinther M; Buijs J; Que I; Löwik C; van der Pluijm G; ten Dijke P
Cancer Res; 2006 Feb; 66(4):2202-9. PubMed ID: 16489022
[TBL] [Abstract][Full Text] [Related]
15. PDZK1-interacting protein 1 (PDZK1IP1) traps Smad4 protein and suppresses transforming growth factor-β (TGF-β) signaling.
Ikeno S; Nakano N; Sano K; Minowa T; Sato W; Akatsu R; Sakata N; Hanagata N; Fujii M; Itoh F; Itoh S
J Biol Chem; 2019 Mar; 294(13):4966-4980. PubMed ID: 30718277
[TBL] [Abstract][Full Text] [Related]
16. Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas.
Goggins M; Shekher M; Turnacioglu K; Yeo CJ; Hruban RH; Kern SE
Cancer Res; 1998 Dec; 58(23):5329-32. PubMed ID: 9850059
[TBL] [Abstract][Full Text] [Related]
17. Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
Grau AM; Zhang L; Wang W; Ruan S; Evans DB; Abbruzzese JL; Zhang W; Chiao PJ
Cancer Res; 1997 Sep; 57(18):3929-34. PubMed ID: 9307274
[TBL] [Abstract][Full Text] [Related]
18. Nuclear Respiratory Factor-1, a Novel SMAD4 Binding Protein, Represses TGF-β/SMAD4 Signaling by Functioning as a Transcriptional Cofactor.
Rajasekaran N; Song K; Lee JH; Wei Y; Erkin ÖC; Lee H; Shin YK
Int J Mol Sci; 2021 May; 22(11):. PubMed ID: 34070531
[TBL] [Abstract][Full Text] [Related]
19. Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.
Levy L; Hill CS
Mol Cell Biol; 2005 Sep; 25(18):8108-25. PubMed ID: 16135802
[TBL] [Abstract][Full Text] [Related]
20. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.
de Winter JP; Roelen BA; ten Dijke P; van der Burg B; van den Eijnden-van Raaij AJ
Oncogene; 1997 Apr; 14(16):1891-9. PubMed ID: 9150356
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
