BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

343 related articles for article (PubMed ID: 30668728)

  • 1. Nearly complete deletion of BubR1 causes microcephaly through shortened mitosis and massive cell death.
    Simmons AJ; Park R; Sterling NA; Jang MH; van Deursen JMA; Yen TJ; Cho SH; Kim S
    Hum Mol Genet; 2019 Jun; 28(11):1822-1836. PubMed ID: 30668728
    [TBL] [Abstract][Full Text] [Related]  

  • 2. P53 independent pathogenic mechanisms contribute to BubR1 microcephaly.
    Sterling NA; Terry BK; McDonnell JM; Kim S
    Front Cell Dev Biol; 2023; 11():1282182. PubMed ID: 37900274
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome.
    Matsuura S; Matsumoto Y; Morishima K; Izumi H; Matsumoto H; Ito E; Tsutsui K; Kobayashi J; Tauchi H; Kajiwara Y; Hama S; Kurisu K; Tahara H; Oshimura M; Komatsu K; Ikeuchi T; Kajii T
    Am J Med Genet A; 2006 Feb; 140(4):358-67. PubMed ID: 16411201
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Research progress on spindle assembly checkpoint gene BubR1].
    Chen ZJ; Li F; Yang J
    Zhejiang Da Xue Xue Bao Yi Xue Ban; 2011 Jul; 40(4):446-50. PubMed ID: 21845762
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation.
    Wijshake T; Malureanu LA; Baker DJ; Jeganathan KB; van de Sluis B; van Deursen JM
    PLoS Genet; 2012; 8(12):e1003138. PubMed ID: 23300461
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mosaic variegated aneuploidy in mouse BubR1 deficient embryos and pregnancy loss in human.
    Schmid M; Steinlein C; Tian Q; Hanlon Newell AE; Gessler M; Olson SB; Rosenwald A; Kneitz B; Fedorov LM
    Chromosome Res; 2014 Sep; 22(3):375-92. PubMed ID: 24981203
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells.
    Sakai D; Dixon J; Dixon MJ; Trainor PA
    PLoS Genet; 2012; 8(3):e1002566. PubMed ID: 22479190
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy.
    Suijkerbuijk SJ; van Osch MH; Bos FL; Hanks S; Rahman N; Kops GJ
    Cancer Res; 2010 Jun; 70(12):4891-900. PubMed ID: 20516114
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insufficiency of BUBR1, a mitotic spindle checkpoint regulator, causes impaired ciliogenesis in vertebrates.
    Miyamoto T; Porazinski S; Wang H; Borovina A; Ciruna B; Shimizu A; Kajii T; Kikuchi A; Furutani-Seiki M; Matsuura S
    Hum Mol Genet; 2011 May; 20(10):2058-70. PubMed ID: 21389084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors.
    Lizarraga SB; Margossian SP; Harris MH; Campagna DR; Han AP; Blevins S; Mudbhary R; Barker JE; Walsh CA; Fleming MD
    Development; 2010 Jun; 137(11):1907-17. PubMed ID: 20460369
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Age-related decline in BubR1 impairs adult hippocampal neurogenesis.
    Yang Z; Jun H; Choi CI; Yoo KH; Cho CH; Hussaini SMQ; Simmons AJ; Kim S; van Deursen JM; Baker DJ; Jang MH
    Aging Cell; 2017 Jun; 16(3):598-601. PubMed ID: 28383136
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation.
    Park I; Lee HO; Choi E; Lee YK; Kwon MS; Min J; Park PG; Lee S; Kong YY; Gong G; Lee H
    J Cell Biol; 2013 Jul; 202(2):295-309. PubMed ID: 23878276
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.
    Sieben CJ; Jeganathan KB; Nelson GG; Sturmlechner I; Zhang C; van Deursen WH; Bakker B; Foijer F; Li H; Baker DJ; van Deursen JM
    J Clin Invest; 2020 Jan; 130(1):171-188. PubMed ID: 31738183
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gradual reduction of BUBR1 protein levels results in premature sister-chromatid separation then in aneuploidy.
    Bohers E; Sarafan-Vasseur N; Drouet A; Paresy M; Latouche JB; Flaman JM; Sesboüé R; Frebourg T
    Hum Genet; 2008 Dec; 124(5):473-8. PubMed ID: 18932004
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.
    Elowe S; Dulla K; Uldschmid A; Li X; Dou Z; Nigg EA
    J Cell Sci; 2010 Jan; 123(Pt 1):84-94. PubMed ID: 20016069
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis.
    Martin CA; Murray JE; Carroll P; Leitch A; Mackenzie KJ; Halachev M; Fetit AE; Keith C; Bicknell LS; Fluteau A; Gautier P; Hall EA; Joss S; Soares G; Silva J; Bober MB; Duker A; Wise CA; Quigley AJ; Phadke SR; ; Wood AJ; Vagnarelli P; Jackson AP
    Genes Dev; 2016 Oct; 30(19):2158-2172. PubMed ID: 27737959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pathogenic correlation between mosaic variegated aneuploidy 1 (MVA1) and a novel BUB1B variant: a reappraisal of a severe syndrome.
    Pavone P; Pappalardo XG; Mustafa N; Falsaperla R; Marino SD; Corsello G; Bianca S; Parano E; Ruggieri M
    Neurol Sci; 2022 Nov; 43(11):6529-6538. PubMed ID: 35804254
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sumoylated BubR1 plays an important role in chromosome segregation and mitotic timing.
    Yang F; Huang Y; Dai W
    Cell Cycle; 2012 Feb; 11(4):797-806. PubMed ID: 22374677
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.
    Ditchfield C; Johnson VL; Tighe A; Ellston R; Haworth C; Johnson T; Mortlock A; Keen N; Taylor SS
    J Cell Biol; 2003 Apr; 161(2):267-80. PubMed ID: 12719470
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of the role of GSK3 in the mitotic checkpoint.
    Rashid MS; Mazur T; Ji W; Liu ST; Taylor WR
    Sci Rep; 2018 Sep; 8(1):14259. PubMed ID: 30250048
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.