These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 30672911)

  • 1. Sterol A-ring plasticity in hedgehog protein cholesterolysis supports a primitive substrate selectivity mechanism.
    Ciulla DA; Wagner AG; Liu X; Cooper CL; Jorgensen MT; Wang C; Goyal P; Banavali NK; Pezzullo JL; Giner JL; Callahan BP
    Chem Commun (Camb); 2019 Feb; 55(12):1829-1832. PubMed ID: 30672911
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein-Nucleic Acid Conjugation with Sterol Linkers Using Hedgehog Autoprocessing.
    Zhang X; Xu Z; Moumin DS; Ciulla DA; Owen TS; Mancusi RA; Giner JL; Wang C; Callahan BP
    Bioconjug Chem; 2019 Nov; 30(11):2799-2804. PubMed ID: 31600061
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nanomolar, Noncovalent Antagonism of Hedgehog Cholesterolysis: Exception to the "Irreversibility Rule" for Protein Autoprocessing Inhibition.
    Wagner AG; Stagnitta RT; Xu Z; Pezzullo JL; Kandel N; Giner JL; Covey DF; Wang C; Callahan BP
    Biochemistry; 2022 Jun; 61(11):1022-1028. PubMed ID: 34941260
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemical Bypass of General Base Catalysis in Hedgehog Protein Cholesterolysis Using a Hyper-Nucleophilic Substrate.
    Ciulla DA; Jorgensen MT; Giner JL; Callahan BP
    J Am Chem Soc; 2018 Jan; 140(3):916-918. PubMed ID: 28930454
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Mechanism of Cholesterol Modification of Hedgehog Ligand.
    Banavali NK
    J Comput Chem; 2020 Mar; 41(6):520-527. PubMed ID: 31823413
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hedgehog proteins create a dynamic cholesterol interface.
    Mafi A; Purohit R; Vielmas E; Lauinger AR; Lam B; Cheng YS; Zhang T; Huang Y; Kim SK; Goddard WA; Ondrus AE
    PLoS One; 2021; 16(2):e0246814. PubMed ID: 33630857
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Förster resonance energy transfer-based cholesterolysis assay identifies a novel hedgehog inhibitor.
    Owen TS; Ngoje G; Lageman TJ; Bordeau BM; Belfort M; Callahan BP
    Anal Biochem; 2015 Nov; 488():1-5. PubMed ID: 26095399
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis of sterol recognition by human hedgehog receptor PTCH1.
    Qi C; Di Minin G; Vercellino I; Wutz A; Korkhov VM
    Sci Adv; 2019 Sep; 5(9):eaaw6490. PubMed ID: 31555730
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dual roles of the sterol recognition region in Hedgehog protein modification.
    Purohit R; Peng DS; Vielmas E; Ondrus AE
    Commun Biol; 2020 May; 3(1):250. PubMed ID: 32440000
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
    Huang P; Nedelcu D; Watanabe M; Jao C; Kim Y; Liu J; Salic A
    Cell; 2016 Aug; 166(5):1176-1187.e14. PubMed ID: 27545348
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sterol regulation of developmental and oncogenic Hedgehog signaling.
    Daggubati V; Raleigh DR; Sever N
    Biochem Pharmacol; 2022 Feb; 196():114647. PubMed ID: 34111427
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis.
    Smith CJ; Wagner AG; Stagnitta RT; Xu Z; Pezzullo JL; Giner JL; Xie J; Covey DF; Wang C; Callahan BP
    Biochemistry; 2020 Feb; 59(6):736-741. PubMed ID: 32013401
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Paracatalytic induction: Subverting specificity in hedgehog protein autoprocessing with small molecules.
    Ciulla DA; Xu Z; Pezzullo JL; Dranchak P; Wang C; Giner JL; Inglese J; Callahan BP
    Methods Enzymol; 2023; 685():1-41. PubMed ID: 37245899
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction of the P-Glycoprotein Multidrug Transporter with Sterols.
    Clay AT; Lu P; Sharom FJ
    Biochemistry; 2015 Nov; 54(43):6586-97. PubMed ID: 26484739
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Steroidogenic acute regulatory protein binds cholesterol and modulates mitochondrial membrane sterol domain dynamics.
    Petrescu AD; Gallegos AM; Okamura Y; Strauss JF; Schroeder F
    J Biol Chem; 2001 Oct; 276(40):36970-82. PubMed ID: 11489878
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response.
    Myers BR; Sever N; Chong YC; Kim J; Belani JD; Rychnovsky S; Bazan JF; Beachy PA
    Dev Cell; 2013 Aug; 26(4):346-57. PubMed ID: 23954590
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural dissection of sterol glycosyltransferase UGT51 from Saccharomyces cerevisiae for substrate specificity.
    Chen L; Zhang Y; Feng Y
    J Struct Biol; 2018 Dec; 204(3):371-379. PubMed ID: 30395931
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators.
    Ciulla DA; Dranchak P; Pezzullo JL; Mancusi RA; Psaras AM; Rai G; Giner JL; Inglese J; Callahan BP
    J Biol Chem; 2022 Dec; 298(12):102705. PubMed ID: 36400200
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Active site targeting of hedgehog precursor protein with phenylarsine oxide.
    Owen TS; Xie XJ; Laraway B; Ngoje G; Wang C; Callahan BP
    Chembiochem; 2015 Jan; 16(1):55-8. PubMed ID: 25418613
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bioorthogonal probes for imaging sterols in cells.
    Jao CY; Nedelcu D; Lopez LV; Samarakoon TN; Welti R; Salic A
    Chembiochem; 2015 Mar; 16(4):611-7. PubMed ID: 25663046
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.