These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
199 related articles for article (PubMed ID: 30675521)
1. MEP50/PRMT5-mediated methylation activates GLI1 in Hedgehog signalling through inhibition of ubiquitination by the ITCH/NUMB complex. Abe Y; Suzuki Y; Kawamura K; Tanaka N Commun Biol; 2019; 2():23. PubMed ID: 30675521 [TBL] [Abstract][Full Text] [Related]
2. Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal. Di Marcotullio L; Greco A; Mazzà D; Canettieri G; Pietrosanti L; Infante P; Coni S; Moretti M; De Smaele E; Ferretti E; Screpanti I; Gulino A Oncogene; 2011 Jan; 30(1):65-76. PubMed ID: 20818436 [TBL] [Abstract][Full Text] [Related]
3. Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination. Di Marcotullio L; Ferretti E; Greco A; De Smaele E; Po A; Sico MA; Alimandi M; Giannini G; Maroder M; Screpanti I; Gulino A Nat Cell Biol; 2006 Dec; 8(12):1415-23. PubMed ID: 17115028 [TBL] [Abstract][Full Text] [Related]
4. Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene Expression. Saha K; Eckert RL J Biol Chem; 2015 May; 290(21):13521-30. PubMed ID: 25851901 [TBL] [Abstract][Full Text] [Related]
5. MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling. Saha K; Adhikary G; Eckert RL J Invest Dermatol; 2016 Jan; 136(1):214-224. PubMed ID: 26763441 [TBL] [Abstract][Full Text] [Related]
6. Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase. Burgos ES; Wilczek C; Onikubo T; Bonanno JB; Jansong J; Reimer U; Shechter D J Biol Chem; 2015 Apr; 290(15):9674-89. PubMed ID: 25713080 [TBL] [Abstract][Full Text] [Related]
7. Discovery and Biological Characterization of PRMT5:MEP50 Protein-Protein Interaction Inhibitors. Asberry AM; Cai X; Deng X; Santiago U; Liu S; Sims HS; Liang W; Xu X; Wan J; Jiang W; Camacho CJ; Dai M; Hu CD J Med Chem; 2022 Oct; 65(20):13793-13812. PubMed ID: 36206451 [TBL] [Abstract][Full Text] [Related]
8. Methylosome protein 50 promotes androgen- and estrogen-independent tumorigenesis. Wei TY; Hsia JY; Chiu SC; Su LJ; Juan CC; Lee YC; Chen JM; Chou HY; Huang JY; Huang HM; Yu CT Cell Signal; 2014 Dec; 26(12):2940-50. PubMed ID: 25277535 [TBL] [Abstract][Full Text] [Related]
9. The Structure and Function of the PRMT5:MEP50 Complex. Antonysamy S Subcell Biochem; 2017; 83():185-194. PubMed ID: 28271477 [TBL] [Abstract][Full Text] [Related]
10. Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion. Wang M; Fuhrmann J; Thompson PR Biochemistry; 2014 Dec; 53(50):7884-92. PubMed ID: 25485739 [TBL] [Abstract][Full Text] [Related]
11. A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression. Chen H; Lorton B; Gupta V; Shechter D Oncogene; 2017 Jan; 36(3):373-386. PubMed ID: 27270440 [TBL] [Abstract][Full Text] [Related]
12. The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond. Stopa N; Krebs JE; Shechter D Cell Mol Life Sci; 2015 Jun; 72(11):2041-59. PubMed ID: 25662273 [TBL] [Abstract][Full Text] [Related]
13. Sulforaphane inhibits PRMT5 and MEP50 function to suppress the mesothelioma cancer cell phenotype. Ezeka G; Adhikary G; Kandasamy S; Friedberg JS; Eckert RL Mol Carcinog; 2021 Jul; 60(7):429-439. PubMed ID: 33872411 [TBL] [Abstract][Full Text] [Related]
14. Targeting Hedgehog Signalling through the Ubiquitylation Process: The Multiple Roles of the HECT-E3 Ligase Itch. Infante P; Lospinoso Severini L; Bernardi F; Bufalieri F; Di Marcotullio L Cells; 2019 Jan; 8(2):. PubMed ID: 30699938 [TBL] [Abstract][Full Text] [Related]
15. Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2 Ichikawa T; Suekane A; Nakahata S; Iha H; Shimoda K; Murakami T; Morishita K Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38474089 [TBL] [Abstract][Full Text] [Related]
16. Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development. Lin C; Chen MH; Yao E; Song H; Gacayan R; Hui CC; Chuang PT Dev Biol; 2014 Aug; 392(2):324-33. PubMed ID: 24886827 [TBL] [Abstract][Full Text] [Related]
17. Lead induces the up-regulation of the protein arginine methyltransferase 5 possibly by its promoter demethylation. Ghosh K; Chatterjee B; Kanade SR Biochem J; 2018 Aug; 475(16):2653-2666. PubMed ID: 30054435 [TBL] [Abstract][Full Text] [Related]
18. PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours. Yuan HF; Zhao M; Zhao LN; Yun HL; Yang G; Geng Y; Wang YF; Zheng W; Yuan Y; Song TQ; Niu JQ; Zhang XD Acta Pharmacol Sin; 2022 Sep; 43(9):2373-2385. PubMed ID: 35046516 [TBL] [Abstract][Full Text] [Related]
19. Menin directly represses Gli1 expression independent of canonical Hedgehog signaling. Gurung B; Feng Z; Hua X Mol Cancer Res; 2013 Oct; 11(10):1215-22. PubMed ID: 23928057 [TBL] [Abstract][Full Text] [Related]
20. Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation. Saha K; Fisher ML; Adhikary G; Grun D; Eckert RL Carcinogenesis; 2017 Aug; 38(8):827-836. PubMed ID: 28854561 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]