These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 30679310)

  • 1. The metastasis suppressor NDRG1 down-regulates the epidermal growth factor receptor via a lysosomal mechanism by up-regulating mitogen-inducible gene 6.
    Menezes SV; Kovacevic Z; Richardson DR
    J Biol Chem; 2019 Mar; 294(11):4045-4064. PubMed ID: 30679310
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.
    Kovacevic Z; Menezes SV; Sahni S; Kalinowski DS; Bae DH; Lane DJ; Richardson DR
    J Biol Chem; 2016 Jan; 291(3):1029-52. PubMed ID: 26534963
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thiosemicarbazones suppress expression of the c-Met oncogene by mechanisms involving lysosomal degradation and intracellular shedding.
    Park KC; Geleta B; Leck LYW; Paluncic J; Chiang S; Jansson PJ; Kovacevic Z; Richardson DR
    J Biol Chem; 2020 Jan; 295(2):481-503. PubMed ID: 31744884
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Type I γ Phosphatidylinositol Phosphate 5-Kinase i5 Controls the Ubiquitination and Degradation of the Tumor Suppressor Mitogen-inducible Gene 6.
    Sun M; Cai J; Anderson RA; Sun Y
    J Biol Chem; 2016 Oct; 291(41):21461-21473. PubMed ID: 27557663
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling.
    Menezes SV; Sahni S; Kovacevic Z; Richardson DR
    J Biol Chem; 2017 Aug; 292(31):12772-12782. PubMed ID: 28615452
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNAJB1 negatively regulates MIG6 to promote epidermal growth factor receptor signaling.
    Park SY; Choi HK; Seo JS; Yoo JY; Jeong JW; Choi Y; Choi KC; Yoon HG
    Biochim Biophys Acta; 2015 Oct; 1853(10 Pt A):2722-30. PubMed ID: 26239118
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The induction of MIG6 under hypoxic conditions is critical for dormancy in primary cultured lung cancer cells with activating EGFR mutations.
    Endo H; Okami J; Okuyama H; Nishizawa Y; Imamura F; Inoue M
    Oncogene; 2017 May; 36(20):2824-2834. PubMed ID: 27893711
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of EGFR trafficking and cell signaling by Sprouty2 and MIG6 in lung cancer cells.
    Walsh AM; Lazzara MJ
    J Cell Sci; 2013 Oct; 126(Pt 19):4339-48. PubMed ID: 23868981
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.
    Fang BA; Kovačević Ž; Park KC; Kalinowski DS; Jansson PJ; Lane DJ; Sahni S; Richardson DR
    Biochim Biophys Acta; 2014 Jan; 1845(1):1-19. PubMed ID: 24269900
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways.
    Kovacevic Z; Chikhani S; Lui GY; Sivagurunathan S; Richardson DR
    Antioxid Redox Signal; 2013 Mar; 18(8):874-87. PubMed ID: 22462691
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1.
    Liu W; Yue F; Zheng M; Merlot A; Bae DH; Huang M; Lane D; Jansson P; Lui GY; Richardson V; Sahni S; Kalinowski D; Kovacevic Z; Richardson DR
    Oncotarget; 2015 Apr; 6(11):8851-74. PubMed ID: 25860930
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The TGFβ-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors.
    Izumchenko E; Chang X; Michailidi C; Kagohara L; Ravi R; Paz K; Brait M; Hoque MO; Ling S; Bedi A; Sidransky D
    Cancer Res; 2014 Jul; 74(14):3995-4005. PubMed ID: 24830724
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma.
    Maity TK; Venugopalan A; Linnoila I; Cultraro CM; Giannakou A; Nemati R; Zhang X; Webster JD; Ritt D; Ghosal S; Hoschuetzky H; Simpson RM; Biswas R; Politi K; Morrison DK; Varmus HE; Guha U
    Cancer Discov; 2015 May; 5(5):534-49. PubMed ID: 25735773
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mig6 reduces inflammatory mediators production by regulating the activation of EGFR in LPS-induced endotoxemia.
    Chen W; Zhong H; Wang X; Pang Q; Zhuang J; Hu J; Chen Y; Hu J; Liu J; Tang J
    J Cell Physiol; 2018 Sep; 233(9):6975-6983. PubMed ID: 29336487
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MEF2C promotes gefitinib resistance in hepatic cancer cells through regulating MIG6 transcription.
    Zhang H; Liu W; Wang Z; Meng L; Wang Y; Yan H; Li L
    Tumori; 2018 Jun; 104(3):221-231. PubMed ID: 29714661
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NDRG1 suppresses basal and hypoxia-induced autophagy at both the initiation and degradation stages and sensitizes pancreatic cancer cells to lysosomal membrane permeabilization.
    Sahni S; Gillson J; Park KC; Chiang S; Leck LYW; Jansson PJ; Richardson DR
    Biochim Biophys Acta Gen Subj; 2020 Aug; 1864(8):129625. PubMed ID: 32335136
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exploring the interactions of EGFR with phosphorylated Mig6 by molecular dynamics simulations and MM-PBSA calculations.
    Zhang Y; Zheng QC
    J Theor Biol; 2018 Jun; 447():118-125. PubMed ID: 29574142
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of Mig6 negatively regulates the ubiquitination and degradation of EGFR mutants in lung adenocarcinoma cell lines.
    Boopathy GTK; Lynn JLS; Wee S; Gunaratne J; Hong W
    Cell Signal; 2018 Mar; 43():21-31. PubMed ID: 29196224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells.
    Siu A; Virtanen C; Jongstra J
    Oncotarget; 2011 Dec; 2(12):1134-44. PubMed ID: 22193779
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential parsing of EGFR endocytic flux among parallel internalization pathways in lung cancer cells with EGFR-activating mutations.
    Walsh AM; Lazzara MJ
    Integr Biol (Camb); 2014 Mar; 6(3):312-23. PubMed ID: 24445374
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.