387 related articles for article (PubMed ID: 30679434)
1. IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling.
Sheng X; Nenseth HZ; Qu S; Kuzu OF; Frahnow T; Simon L; Greene S; Zeng Q; Fazli L; Rennie PS; Mills IG; Danielsen H; Theis F; Patterson JB; Jin Y; Saatcioglu F
Nat Commun; 2019 Jan; 10(1):323. PubMed ID: 30679434
[TBL] [Abstract][Full Text] [Related]
2. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
Merlot AM; Shafie NH; Yu Y; Richardson V; Jansson PJ; Sahni S; Lane DJR; Kovacevic Z; Kalinowski DS; Richardson DR
Biochem Pharmacol; 2016 Jun; 109():27-47. PubMed ID: 27059255
[TBL] [Abstract][Full Text] [Related]
3. IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling.
Chen C; Zhang X
J Transl Med; 2017 Feb; 15(1):42. PubMed ID: 28222747
[TBL] [Abstract][Full Text] [Related]
4. Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
Zhao N; Cao J; Xu L; Tang Q; Dobrolecki LE; Lv X; Talukdar M; Lu Y; Wang X; Hu DZ; Shi Q; Xiang Y; Wang Y; Liu X; Bu W; Jiang Y; Li M; Gong Y; Sun Z; Ying H; Yuan B; Lin X; Feng XH; Hartig SM; Li F; Shen H; Chen Y; Han L; Zeng Q; Patterson JB; Kaipparettu BA; Putluri N; Sicheri F; Rosen JM; Lewis MT; Chen X
J Clin Invest; 2018 Apr; 128(4):1283-1299. PubMed ID: 29480818
[TBL] [Abstract][Full Text] [Related]
5. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer.
Lin J; Liu H; Fukumoto T; Zundell J; Yan Q; Tang CA; Wu S; Zhou W; Guo D; Karakashev S; Hu CA; Sarma K; Kossenkov AV; Zhang R
Nat Commun; 2021 Sep; 12(1):5321. PubMed ID: 34493732
[TBL] [Abstract][Full Text] [Related]
6. IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers.
Xie H; Tang CH; Song JH; Mancuso A; Del Valle JR; Cao J; Xiang Y; Dang CV; Lan R; Sanchez DJ; Keith B; Hu CC; Simon MC
J Clin Invest; 2018 Apr; 128(4):1300-1316. PubMed ID: 29381485
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia.
Sun H; Lin DC; Guo X; Kharabi Masouleh B; Gery S; Cao Q; Alkan S; Ikezoe T; Akiba C; Paquette R; Chien W; Müller-Tidow C; Jing Y; Agelopoulos K; Müschen M; Koeffler HP
Oncotarget; 2016 Apr; 7(14):18736-49. PubMed ID: 26934650
[TBL] [Abstract][Full Text] [Related]
8. 17-Aminogeldanamycin selectively diminishes IRE1α-XBP1s pathway activity and cooperatively induces apoptosis with MEK1/2 and BRAF
Mielczarek-Lewandowska A; Sztiller-Sikorska M; Osrodek M; Czyz M; Hartman ML
Apoptosis; 2019 Aug; 24(7-8):596-611. PubMed ID: 30989459
[TBL] [Abstract][Full Text] [Related]
9. IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8
Medel B; Costoya C; Fernandez D; Pereda C; Lladser A; Sauma D; Pacheco R; Iwawaki T; Salazar-Onfray F; Osorio F
Front Immunol; 2018; 9():3050. PubMed ID: 30687308
[TBL] [Abstract][Full Text] [Related]
10. Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
Liu X; Guo GL; Kong B; Hilburn DB; Hubchak SC; Park S; LeCuyer B; Hsieh A; Wang L; Fang D; Green RM
Hepatology; 2018 Jul; 68(1):304-316. PubMed ID: 29377207
[TBL] [Abstract][Full Text] [Related]
11. IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.
Han X; Zhou J; Zhang P; Song F; Jiang R; Li M; Xia F; Guo FJ
Cell Signal; 2013 Nov; 25(11):2136-46. PubMed ID: 23816533
[TBL] [Abstract][Full Text] [Related]
12. Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.
Jiang D; Tam AB; Alagappan M; Hay MP; Gupta A; Kozak MM; Solow-Cordero DE; Lum PY; Denko NC; Giaccia AJ; Le QT; Niwa M; Koong AC
Mol Cancer Ther; 2016 Sep; 15(9):2055-65. PubMed ID: 27307600
[TBL] [Abstract][Full Text] [Related]
13. ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
Blazanin N; Son J; Craig-Lucas AB; John CL; Breech KJ; Podolsky MA; Glick AB
Proc Natl Acad Sci U S A; 2017 Sep; 114(37):9900-9905. PubMed ID: 28847931
[TBL] [Abstract][Full Text] [Related]
14. A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1.
Ming J; Ruan S; Wang M; Ye D; Fan N; Meng Q; Tian B; Huang T
Oncotarget; 2015 Dec; 6(38):40692-703. PubMed ID: 26517687
[TBL] [Abstract][Full Text] [Related]
15. Disruption of IRE1α through its kinase domain attenuates multiple myeloma.
Harnoss JM; Le Thomas A; Shemorry A; Marsters SA; Lawrence DA; Lu M; Chen YA; Qing J; Totpal K; Kan D; Segal E; Merchant M; Reichelt M; Ackerly Wallweber H; Wang W; Clark K; Kaufman S; Beresini MH; Laing ST; Sandoval W; Lorenzo M; Wu J; Ly J; De Bruyn T; Heidersbach A; Haley B; Gogineni A; Weimer RM; Lee D; Braun MG; Rudolph J; VanWyngarden MJ; Sherbenou DW; Gomez-Bougie P; Amiot M; Acosta-Alvear D; Walter P; Ashkenazi A
Proc Natl Acad Sci U S A; 2019 Aug; 116(33):16420-16429. PubMed ID: 31371506
[TBL] [Abstract][Full Text] [Related]
16. Arsenite Induces Vascular Endothelial Cell Dysfunction by Activating IRE1α/XBP1s/HIF1α-Dependent ANGII Signaling.
Xu X; Liu S; Aodengqimuge ; Wang H; Hu M; Xing C; Song L
Toxicol Sci; 2017 Dec; 160(2):315-328. PubMed ID: 28973481
[TBL] [Abstract][Full Text] [Related]
17. Inhibiting the IRE1α Axis of the Unfolded Protein Response Enhances the Antitumor Effect of AZD1775 in TP53 Mutant Ovarian Cancer.
Xiao R; You L; Zhang L; Guo X; Guo E; Zhao F; Yang B; Li X; Fu Y; Lu F; Wang Z; Liu C; Peng W; Li W; Yang X; Dou Y; Liu J; Wang W; Qin T; Cui Y; Zhang X; Li F; Jin Y; Zeng Q; Wang B; Mills GB; Chen G; Sheng X; Sun C
Adv Sci (Weinh); 2022 Jul; 9(21):e2105469. PubMed ID: 35619328
[TBL] [Abstract][Full Text] [Related]
18. Androgen modulation of XBP1 is functionally driving part of the AR transcriptional program.
Stelloo S; Linder S; Nevedomskaya E; Valle-Encinas E; de Rink I; Wessels LFA; van der Poel H; Bergman AM; Zwart W
Endocr Relat Cancer; 2020 Feb; 27(2):67-79. PubMed ID: 31804970
[TBL] [Abstract][Full Text] [Related]
19. IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.
Harnoss JM; Le Thomas A; Reichelt M; Guttman O; Wu TD; Marsters SA; Shemorry A; Lawrence DA; Kan D; Segal E; Merchant M; Totpal K; Crocker LM; Mesh K; Dohse M; Solon M; Modrusan Z; Rudolph J; Koeppen H; Walter P; Ashkenazi A
Cancer Res; 2020 Jun; 80(11):2368-2379. PubMed ID: 32265225
[TBL] [Abstract][Full Text] [Related]
20. Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in
Zundell JA; Fukumoto T; Lin J; Fatkhudinov N; Nacarelli T; Kossenkov AV; Liu Q; Cassel J; Hu CA; Wu S; Zhang R
Cancer Res; 2021 Oct; 81(20):5325-5335. PubMed ID: 34548333
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
