BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 30684133)

  • 41. CBAP modulates Akt-dependent TSC2 phosphorylation to promote Rheb-mTORC1 signaling and growth of T-cell acute lymphoblastic leukemia.
    Chiang YJ; Liao WT; Ho KC; Wang SH; Chen YG; Ho CL; Huang SF; Shih LY; Yang-Yen HF; Yen JJ
    Oncogene; 2019 Feb; 38(9):1432-1447. PubMed ID: 30266989
    [TBL] [Abstract][Full Text] [Related]  

  • 42. A complex interplay between Akt, TSC2 and the two mTOR complexes.
    Huang J; Manning BD
    Biochem Soc Trans; 2009 Feb; 37(Pt 1):217-22. PubMed ID: 19143635
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling.
    Stevens C; Lin Y; Harrison B; Burch L; Ridgway RA; Sansom O; Hupp T
    J Biol Chem; 2009 Jan; 284(1):334-344. PubMed ID: 18974095
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells.
    Misra UK; Pizzo SV
    PLoS One; 2012; 7(12):e51735. PubMed ID: 23272152
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK.
    Zhou H; Shang C; Wang M; Shen T; Kong L; Yu C; Ye Z; Luo Y; Liu L; Li Y; Huang S
    Biochem Pharmacol; 2016 Sep; 116():39-50. PubMed ID: 27396756
    [TBL] [Abstract][Full Text] [Related]  

  • 46. cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.
    Xie J; Ponuwei GA; Moore CE; Willars GB; Tee AR; Herbert TP
    Cell Signal; 2011 Dec; 23(12):1927-35. PubMed ID: 21763421
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis.
    Xie J; Shen K; Jones AT; Yang J; Tee AR; Shen MH; Yu M; Irani S; Wong D; Merrett JE; Lenchine RV; De Poi S; Jensen KB; Trim PJ; Snel MF; Kamei M; Martin SK; Fitter S; Tian S; Wang X; Butler LM; Zannettino ACW; Proud CG
    Cell Mol Life Sci; 2021 Jan; 78(1):249-270. PubMed ID: 32170339
    [TBL] [Abstract][Full Text] [Related]  

  • 48. AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells.
    Agarwal S; Bell CM; Rothbart SB; Moran RG
    J Biol Chem; 2015 Nov; 290(46):27473-86. PubMed ID: 26391395
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Pharmacological intervention to restore connectivity deficits of neuronal networks derived from ASD patient iPSC with a TSC2 mutation.
    Alsaqati M; Heine VM; Harwood AJ
    Mol Autism; 2020 Oct; 11(1):80. PubMed ID: 33076974
    [TBL] [Abstract][Full Text] [Related]  

  • 50. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling.
    Bartolomé A; García-Aguilar A; Asahara SI; Kido Y; Guillén C; Pajvani UB; Benito M
    Mol Cell Biol; 2017 Dec; 37(23):. PubMed ID: 28894028
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Regulation of mTORC1 signaling by pH.
    Balgi AD; Diering GH; Donohue E; Lam KK; Fonseca BD; Zimmerman C; Numata M; Roberge M
    PLoS One; 2011; 6(6):e21549. PubMed ID: 21738705
    [TBL] [Abstract][Full Text] [Related]  

  • 52. The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis.
    Spangle JM; Münger K
    J Virol; 2010 Sep; 84(18):9398-407. PubMed ID: 20631133
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia.
    Wolff NC; Vega-Rubin-de-Celis S; Xie XJ; Castrillon DH; Kabbani W; Brugarolas J
    Mol Cell Biol; 2011 May; 31(9):1870-84. PubMed ID: 21383064
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling.
    Miyazaki M; McCarthy JJ; Fedele MJ; Esser KA
    J Physiol; 2011 Apr; 589(Pt 7):1831-46. PubMed ID: 21300751
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Upregulation of C/EBPβ and TSC2 by an HDAC inhibitor CG200745 protects heart from DOCA-induced hypertrophy.
    Lee E; Lee HA; Kim M; Do GY; Cho HM; Kim GJ; Jung H; Song JH; Cho JM; Kim I
    Clin Exp Pharmacol Physiol; 2019 Mar; 46(3):226-236. PubMed ID: 30099761
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Fetal brain mTOR signaling activation in tuberous sclerosis complex.
    Tsai V; Parker WE; Orlova KA; Baybis M; Chi AW; Berg BD; Birnbaum JF; Estevez J; Okochi K; Sarnat HB; Flores-Sarnat L; Aronica E; Crino PB
    Cereb Cortex; 2014 Feb; 24(2):315-27. PubMed ID: 23081885
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Design of negative-regulating proteins of Rheb/mTORC1 with much-reduced sizes of the tuberous sclerosis protein complex.
    Fu W; Wu G
    Protein Sci; 2023 Aug; 32(8):e4731. PubMed ID: 37462942
    [TBL] [Abstract][Full Text] [Related]  

  • 58. mTORC1 suppresses PIM3 expression via miR-33 encoded by the SREBP loci.
    Kelsey I; Zbinden M; Byles V; Torrence M; Manning BD
    Sci Rep; 2017 Nov; 7(1):16112. PubMed ID: 29170467
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Diverse signaling mechanisms of mTOR complexes: mTORC1 and mTORC2 in forming a formidable relationship.
    Jhanwar-Uniyal M; Wainwright JV; Mohan AL; Tobias ME; Murali R; Gandhi CD; Schmidt MH
    Adv Biol Regul; 2019 May; 72():51-62. PubMed ID: 31010692
    [TBL] [Abstract][Full Text] [Related]  

  • 60. The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis.
    Kang YJ; Lu MK; Guan KL
    Cell Death Differ; 2011 Jan; 18(1):133-44. PubMed ID: 20616807
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.