160 related articles for article (PubMed ID: 30688458)
1. Rational Use of Heterogeneous Data in Quantitative Structure-Activity Relationship (QSAR) Modeling of Cyclooxygenase/Lipoxygenase Inhibitors.
Lagunin AA; Geronikaki A; Eleftheriou P; Pogodin PV; Zakharov AV
J Chem Inf Model; 2019 Feb; 59(2):713-730. PubMed ID: 30688458
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, anti-inflammatory screening, molecular docking, and COX-1,2/-5-LOX inhibition profile of some novel quinoline derivatives.
Chaaban I; Rizk OH; Ibrahim TM; Henen SS; El-Khawass EM; Bayad AE; El-Ashmawy IM; Nematalla HA
Bioorg Chem; 2018 Aug; 78():220-235. PubMed ID: 29602046
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
Pontiki E; Hadjipavlou-Litina D; Litinas K; Nicolotti O; Carotti A
Eur J Med Chem; 2011 Jan; 46(1):191-200. PubMed ID: 21106277
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
Rao PN; Chen QH; Knaus EE
J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core.
Sisa M; Dvorakova M; Temml V; Jarosova V; Vanek T; Landa P
Eur J Med Chem; 2020 Oct; 204():112620. PubMed ID: 32738413
[TBL] [Abstract][Full Text] [Related]
6. Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.
Moussa G; Alaaeddine R; Alaeddine LM; Nassra R; Belal ASF; Ismail A; El-Yazbi AF; Abdel-Ghany YS; Hazzaa A
Eur J Med Chem; 2018 Jan; 144():635-650. PubMed ID: 29289887
[TBL] [Abstract][Full Text] [Related]
7. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
El-Nagar MKS; Abdu-Allah HHM; Salem OIA; Kafafy AN; Farghaly HSM
Bioorg Chem; 2018 Aug; 78():80-93. PubMed ID: 29550533
[TBL] [Abstract][Full Text] [Related]
8. Cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) selectivity of COX inhibitors.
Sud'ina GF; Pushkareva MA; Shephard P; Klein T
Prostaglandins Leukot Essent Fatty Acids; 2008 Feb; 78(2):99-108. PubMed ID: 18280718
[TBL] [Abstract][Full Text] [Related]
9. Computer-aided discovery of anti-inflammatory thiazolidinones with dual cyclooxygenase/lipoxygenase inhibition.
Geronikaki AA; Lagunin AA; Hadjipavlou-Litina DI; Eleftheriou PT; Filimonov DA; Poroikov VV; Alam I; Saxena AK
J Med Chem; 2008 Mar; 51(6):1601-9. PubMed ID: 18311898
[TBL] [Abstract][Full Text] [Related]
10. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
Abdelgawad MA; Labib MB; Abdel-Latif M
Bioorg Chem; 2017 Oct; 74():212-220. PubMed ID: 28865292
[TBL] [Abstract][Full Text] [Related]
11. QSAR study of dual cyclooxygenase and 5-lipoxygenase inhibitors 2,6-di-tert-butylphenol derivatives.
Ruiz J; Pérez C; Pouplana R
Bioorg Med Chem; 2003 Sep; 11(19):4207-16. PubMed ID: 12951151
[TBL] [Abstract][Full Text] [Related]
12. Essential structural profile of a dual functional inhibitor against cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): molecular docking and 3D-QSAR analyses on DHDMBF analogues.
Zheng M; Zhang Z; Zhu W; Liu H; Luo X; Chen K; Jiang H
Bioorg Med Chem; 2006 May; 14(10):3428-37. PubMed ID: 16458008
[TBL] [Abstract][Full Text] [Related]
13. Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A₂, cyclooxygenases, lipoxygenase and proinflammatory cytokines.
Bukhari SN; Lauro G; Jantan I; Bifulco G; Amjad MW
Bioorg Med Chem; 2014 Aug; 22(15):4151-61. PubMed ID: 24938495
[TBL] [Abstract][Full Text] [Related]
14. SAR and QSAR models of cyclooxygenase-1 (COX-1) inhibitors.
Xi Y; Qin Z; Yan A
SAR QSAR Environ Res; 2018 Oct; 29(10):755-784. PubMed ID: 30274533
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity.
Shrivastava SK; Srivastava P; Bandresh R; Tripathi PN; Tripathi A
Bioorg Med Chem; 2017 Aug; 25(16):4424-4432. PubMed ID: 28669741
[TBL] [Abstract][Full Text] [Related]
16. Benzodioxole-Pyrazole Hybrids as Anti-Inflammatory and Analgesic Agents with COX-1,2/5-LOX Inhibition and Antioxidant Potential.
Abd El Razik HA; Badr MH; Atta AH; Mouneir SM; Abu-Serie MM
Arch Pharm (Weinheim); 2017 May; 350(5):. PubMed ID: 28418202
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors.
Cusan C; Spalluto G; Prato M; Adams M; Bodensieck A; Bauer R; Tubaro A; Bernardi P; Da Ros T
Farmaco; 2005 Apr; 60(4):327-32. PubMed ID: 15848208
[TBL] [Abstract][Full Text] [Related]
18. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
El-Miligy MMM; Hazzaa AA; El-Messmary H; Nassra RA; El-Hawash SAM
Bioorg Chem; 2017 Jun; 72():102-115. PubMed ID: 28390993
[TBL] [Abstract][Full Text] [Related]
19. Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.
Vo NNQ; Nomura Y; Muranaka T; Fukushima EO
J Nat Prod; 2019 Dec; 82(12):3311-3320. PubMed ID: 31774676
[TBL] [Abstract][Full Text] [Related]
20. New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study.
El-Miligy MM; Hazzaa AA; El-Messmary H; Nassra RA; El-Hawash SA
Future Med Chem; 2017 Apr; 9(5):443-468. PubMed ID: 28362117
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
