These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
212 related articles for article (PubMed ID: 30690294)
41. Selumetinib plus dacarbazine versus placebo plus dacarbazine as first-line treatment for BRAF-mutant metastatic melanoma: a phase 2 double-blind randomised study. Robert C; Dummer R; Gutzmer R; Lorigan P; Kim KB; Nyakas M; Arance A; Liszkay G; Schadendorf D; Cantarini M; Spencer S; Middleton MR Lancet Oncol; 2013 Jul; 14(8):733-40. PubMed ID: 23735514 [TBL] [Abstract][Full Text] [Related]
42. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. Flaherty KT; Infante JR; Daud A; Gonzalez R; Kefford RF; Sosman J; Hamid O; Schuchter L; Cebon J; Ibrahim N; Kudchadkar R; Burris HA; Falchook G; Algazi A; Lewis K; Long GV; Puzanov I; Lebowitz P; Singh A; Little S; Sun P; Allred A; Ouellet D; Kim KB; Patel K; Weber J N Engl J Med; 2012 Nov; 367(18):1694-703. PubMed ID: 23020132 [TBL] [Abstract][Full Text] [Related]
43. Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial. Ascierto PA; McArthur GA; Dréno B; Atkinson V; Liszkay G; Di Giacomo AM; Mandalà M; Demidov L; Stroyakovskiy D; Thomas L; de la Cruz-Merino L; Dutriaux C; Garbe C; Yan Y; Wongchenko M; Chang I; Hsu JJ; Koralek DO; Rooney I; Ribas A; Larkin J Lancet Oncol; 2016 Sep; 17(9):1248-60. PubMed ID: 27480103 [TBL] [Abstract][Full Text] [Related]
44. Phase 1/2 study assessing the safety and efficacy of dabrafenib and trametinib combination therapy in Japanese patients with BRAF V600 mutation-positive advanced cutaneous melanoma. Yamazaki N; Tsutsumida A; Takahashi A; Namikawa K; Yoshikawa S; Fujiwara Y; Kondo S; Mukaiyama A; Zhang F; Kiyohara Y J Dermatol; 2018 Apr; 45(4):397-407. PubMed ID: 29399853 [TBL] [Abstract][Full Text] [Related]
45. Combined BRAF and MEK inhibition with PD-1 blockade immunotherapy in BRAF-mutant melanoma. Ribas A; Lawrence D; Atkinson V; Agarwal S; Miller WH; Carlino MS; Fisher R; Long GV; Hodi FS; Tsoi J; Grasso CS; Mookerjee B; Zhao Q; Ghori R; Moreno BH; Ibrahim N; Hamid O Nat Med; 2019 Jun; 25(6):936-940. PubMed ID: 31171879 [TBL] [Abstract][Full Text] [Related]
46. Dabrafenib plus Trametinib: a Review in Advanced Melanoma with a BRAF (V600) Mutation. Dhillon S Target Oncol; 2016 Jun; 11(3):417-28. PubMed ID: 27246822 [TBL] [Abstract][Full Text] [Related]
47. Spartalizumab or placebo in combination with dabrafenib and trametinib in patients with Tawbi HA; Robert C; Brase JC; Gusenleitner D; Gasal E; Garrett J; Savchenko A; Görgün G; Flaherty KT; Ribas A; Dummer R; Schadendorf D; Long GV; Nathan PD; Ascierto PA J Immunother Cancer; 2022 Jun; 10(6):. PubMed ID: 35728875 [TBL] [Abstract][Full Text] [Related]
48. Phase II Clinical Trial of Trametinib and Low-Dose Dabrafenib in Advanced, Previously Treated Awada G; Dirven I; Schwarze JK; Tijtgat J; Fasolino G; Kockx M; Neyns B JCO Precis Oncol; 2024 Oct; 8():e2300493. PubMed ID: 39374099 [TBL] [Abstract][Full Text] [Related]
49. First-line pembrolizumab versus dabrafenib/trametinib treatment for BRAF V600-mutant advanced melanoma. Kim CG; Kim M; Hwang J; Kim ST; Jung M; Kim KH; Kim KH; Chang JS; Koom WS; Roh MR; Chung KY; Kim TM; Kim SK; Lee J; Shin SJ J Am Acad Dermatol; 2022 Nov; 87(5):989-996. PubMed ID: 36068115 [TBL] [Abstract][Full Text] [Related]
50. Overall Survival and Durable Responses in Patients With BRAF V600-Mutant Metastatic Melanoma Receiving Dabrafenib Combined With Trametinib. Long GV; Weber JS; Infante JR; Kim KB; Daud A; Gonzalez R; Sosman JA; Hamid O; Schuchter L; Cebon J; Kefford RF; Lawrence D; Kudchadkar R; Burris HA; Falchook GS; Algazi A; Lewis K; Puzanov I; Ibrahim N; Sun P; Cunningham E; Kline AS; Del Buono H; McDowell DO; Patel K; Flaherty KT J Clin Oncol; 2016 Mar; 34(8):871-8. PubMed ID: 26811525 [TBL] [Abstract][Full Text] [Related]
51. Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma. Ascierto PA; Ferrucci PF; Fisher R; Del Vecchio M; Atkinson V; Schmidt H; Schachter J; Queirolo P; Long GV; Di Giacomo AM; Svane IM; Lotem M; Bar-Sela G; Couture F; Mookerjee B; Ghori R; Ibrahim N; Moreno BH; Ribas A Nat Med; 2019 Jun; 25(6):941-946. PubMed ID: 31171878 [TBL] [Abstract][Full Text] [Related]
52. Factors predictive of response, disease progression, and overall survival after dabrafenib and trametinib combination treatment: a pooled analysis of individual patient data from randomised trials. Long GV; Grob JJ; Nathan P; Ribas A; Robert C; Schadendorf D; Lane SR; Mak C; Legenne P; Flaherty KT; Davies MA Lancet Oncol; 2016 Dec; 17(12):1743-1754. PubMed ID: 27864013 [TBL] [Abstract][Full Text] [Related]
53. Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial. Falchook GS; Lewis KD; Infante JR; Gordon MS; Vogelzang NJ; DeMarini DJ; Sun P; Moy C; Szabo SA; Roadcap LT; Peddareddigari VG; Lebowitz PF; Le NT; Burris HA; Messersmith WA; O'Dwyer PJ; Kim KB; Flaherty K; Bendell JC; Gonzalez R; Kurzrock R; Fecher LA Lancet Oncol; 2012 Aug; 13(8):782-9. PubMed ID: 22805292 [TBL] [Abstract][Full Text] [Related]
54. An open label, non-randomised, phase IIIb study of trametinib in combination with dabrafenib in patients with unresectable (stage III) or distant metastatic (stage IV) BRAF V600-mutant melanoma: A subgroup analysis of patients with brain metastases. Dutriaux C; Robert C; Grob JJ; Mortier L; Dereure O; Lebbe C; Mansard S; Grange F; Neidhardt EM; Lesimple T; Machet L; Bedane C; Maillard H; Dalac-Rat S; Nardin C; Szenik A; Denden A; Saiag P Eur J Cancer; 2022 Nov; 175():254-262. PubMed ID: 36170791 [TBL] [Abstract][Full Text] [Related]
55. COLUMBUS 7-year update: A randomized, open-label, phase III trial of encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF V600E/K-mutant melanoma. Schadendorf D; Dummer R; Flaherty KT; Robert C; Arance A; de Groot JWB; Garbe C; Gogas HJ; Gutzmer R; Krajsová I; Liszkay G; Loquai C; Mandalà M; Yamazaki N; Queirolo P; Guenzel C; Polli A; Thakur M; di Pietro A; Ascierto PA Eur J Cancer; 2024 Jun; 204():114073. PubMed ID: 38723373 [TBL] [Abstract][Full Text] [Related]
56. Five-Year Analysis of Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma. Dummer R; Hauschild A; Santinami M; Atkinson V; Mandalà M; Kirkwood JM; Chiarion Sileni V; Larkin J; Nyakas M; Dutriaux C; Haydon A; Robert C; Mortier L; Schachter J; Lesimple T; Plummer R; Dasgupta K; Gasal E; Tan M; Long GV; Schadendorf D N Engl J Med; 2020 Sep; 383(12):1139-1148. PubMed ID: 32877599 [TBL] [Abstract][Full Text] [Related]
57. Continuous versus intermittent BRAF and MEK inhibition in patients with BRAF-mutated melanoma: a randomized phase 2 trial. Algazi AP; Othus M; Daud AI; Lo RS; Mehnert JM; Truong TG; Conry R; Kendra K; Doolittle GC; Clark JI; Messino MJ; Moore DF; Lao C; Faller BA; Govindarajan R; Harker-Murray A; Dreisbach L; Moon J; Grossmann KF; Ribas A Nat Med; 2020 Oct; 26(10):1564-1568. PubMed ID: 33020646 [TBL] [Abstract][Full Text] [Related]
58. Trametinib (MEKINIST°) Metastatic or inoperable BRAF V600-positive melanoma: a few extra months of life. Prescrire Int; 2016 Dec; 25(177):285-288. PubMed ID: 30758923 [TBL] [Abstract][Full Text] [Related]
59. Outcomes in patients with Aglietta M; Chiarion-Sileni V; Fava P; Guidoboni M; Depenni R; Minisini A; Consoli F; Ascierto PA; Rinaldi G; Banzi M; Marconcini R; Gueli R; Ferraresi V; Tucci M; Tonini G; Lo Re G; Guida M; Del Vecchio M; Marcon IG; Queirolo P Tumori; 2023 Dec; 109(6):537-545. PubMed ID: 37417313 [TBL] [Abstract][Full Text] [Related]