BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 3069131)

  • 1. Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes.
    Zaug AJ; Grosshans CA; Cech TR
    Biochemistry; 1988 Dec; 27(25):8924-31. PubMed ID: 3069131
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site.
    Herschlag D; Cech TR
    Biochemistry; 1990 Nov; 29(44):10159-71. PubMed ID: 2271645
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 2. Kinetic description of the reaction of an RNA substrate that forms a mismatch at the active site.
    Herschlag D; Cech TR
    Biochemistry; 1990 Nov; 29(44):10172-80. PubMed ID: 2271646
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme.
    Grosshans CA; Cech TR
    Biochemistry; 1989 Aug; 28(17):6888-94. PubMed ID: 2684268
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alteration of substrate specificity for the endoribonucleolytic cleavage of RNA by the Tetrahymena ribozyme.
    Murphy FL; Cech TR
    Proc Natl Acad Sci U S A; 1989 Dec; 86(23):9218-22. PubMed ID: 2480597
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Tetrahymena ribozyme acts like an RNA restriction endonuclease.
    Zaug AJ; Been MD; Cech TR
    Nature; 1986 Dec 4-10; 324(6096):429-33. PubMed ID: 3537808
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu).
    Zaug AJ; Dávila-Aponte JA; Cech TR
    Biochemistry; 1994 Dec; 33(49):14935-47. PubMed ID: 7527660
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting.
    McSwiggen JA; Cech TR
    Science; 1989 May; 244(4905):679-83. PubMed ID: 2470150
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom.
    Herschlag D; Piccirilli JA; Cech TR
    Biochemistry; 1991 May; 30(20):4844-54. PubMed ID: 2036355
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction.
    McConnell TS; Herschlag D; Cech TR
    Biochemistry; 1997 Jul; 36(27):8293-303. PubMed ID: 9204875
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Helix P4 is a divalent metal ion binding site in the conserved core of the ribonuclease P ribozyme.
    Christian EL; Kaye NM; Harris ME
    RNA; 2000 Apr; 6(4):511-9. PubMed ID: 10786842
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence for processivity and two-step binding of the RNA substrate from studies of J1/2 mutants of the Tetrahymena ribozyme.
    Herschlag D
    Biochemistry; 1992 Feb; 31(5):1386-99. PubMed ID: 1736996
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fluorescence-detected stopped flow with a pyrene labeled substrate reveals that guanosine facilitates docking of the 5' cleavage site into a high free energy binding mode in the Tetrahymena ribozyme.
    Bevilacqua PC; Li Y; Turner DH
    Biochemistry; 1994 Sep; 33(37):11340-8. PubMed ID: 7727385
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of the mode of binding of substrates to the active site of Tetrahymena self-splicing RNA using 5-fluorouracil-substituted mini-exons.
    Danenberg PV; Shea LC; Danenberg K
    Biochemistry; 1989 Aug; 28(16):6779-85. PubMed ID: 2675974
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA cleavage catalysed by the ribozyme from Tetrahymena.
    Herschlag D; Cech TR
    Nature; 1990 Mar; 344(6265):405-9. PubMed ID: 1690858
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ribozyme recognition of RNA by tertiary interactions with specific ribose 2'-OH groups.
    Pyle AM; Cech TR
    Nature; 1991 Apr; 350(6319):628-31. PubMed ID: 1708111
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reaction conditions and kinetics of self-cleavage of a ribozyme derived from Neurospora VS RNA.
    Collins RA; Olive JE
    Biochemistry; 1993 Mar; 32(11):2795-9. PubMed ID: 7681322
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA.
    Herschlag D; Eckstein F; Cech TR
    Biochemistry; 1993 Aug; 32(32):8299-311. PubMed ID: 7688572
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sequence specificity of a group II intron ribozyme: multiple mechanisms for promoting unusually high discrimination against mismatched targets.
    Xiang Q; Qin PZ; Michels WJ; Freeland K; Pyle AM
    Biochemistry; 1998 Mar; 37(11):3839-49. PubMed ID: 9521704
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evolution in vitro of an RNA enzyme with altered metal dependence.
    Lehman N; Joyce GF
    Nature; 1993 Jan; 361(6408):182-5. PubMed ID: 8421526
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.