BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

355 related articles for article (PubMed ID: 30699353)

  • 1. DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.
    Zhang K; Zhang Y; Xue J; Meng Q; Liu H; Bi C; Li C; Hu L; Yu H; Xiong T; Yang Y; Cui S; Bu Z; He X; Li J; Huang L; Weng C
    Cell Rep; 2019 Jan; 26(5):1258-1272.e4. PubMed ID: 30699353
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKε-IRF3 complex.
    Huang L; Xiong T; Yu H; Zhang Q; Zhang K; Li C; Hu L; Zhang Y; Zhang L; Liu Q; Wang S; He X; Bu Z; Cai X; Cui S; Li J; Weng C
    Biochem J; 2017 Jun; 474(12):2051-2065. PubMed ID: 28487378
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vimentin inhibits type I interferon production by disrupting the TBK1-IKKε-IRF3 axis.
    Liu H; Ye G; Liu X; Xue M; Zhou Q; Zhang L; Zhang K; Huang L; Weng C
    Cell Rep; 2022 Oct; 41(2):111469. PubMed ID: 36223739
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Porcine Deltacoronavirus Accessory Protein NS7a Antagonizes IFN-β Production by Competing With TRAF3 and IRF3 for Binding to IKKε.
    Fang P; Fang L; Xia S; Ren J; Zhang J; Bai D; Zhou Y; Peng G; Zhao S; Xiao S
    Front Cell Infect Microbiol; 2020; 10():257. PubMed ID: 32656094
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Kinase MAP4K1 Inhibits Cytosolic RNA-Induced Antiviral Signaling by Promoting Proteasomal Degradation of TBK1/IKKε.
    He TS; Huang J; Chen T; Zhang Z; Cai K; Yu J; Xu LG
    Microbiol Spectr; 2021 Dec; 9(3):e0145821. PubMed ID: 34908452
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
    Sui L; Zhao Y; Wang W; Wu P; Wang Z; Yu Y; Hou Z; Tan G; Liu Q
    Front Immunol; 2021; 12():662989. PubMed ID: 34084167
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilon and DDX3.
    Yu S; Chen J; Wu M; Chen H; Kato N; Yuan Z
    J Gen Virol; 2010 Aug; 91(Pt 8):2080-2090. PubMed ID: 20375222
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets.
    Yang Y; Ye F; Zhu N; Wang W; Deng Y; Zhao Z; Tan W
    Sci Rep; 2015 Dec; 5():17554. PubMed ID: 26631542
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis.
    Hammaker D; Boyle DL; Firestein GS
    Rheumatology (Oxford); 2012 Apr; 51(4):610-8. PubMed ID: 21613249
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation.
    Schröder M; Baran M; Bowie AG
    EMBO J; 2008 Aug; 27(15):2147-57. PubMed ID: 18636090
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Novel Transcript Isoform of TBK1 Negatively Regulates Type I IFN Production by Promoting Proteasomal Degradation of TBK1 and Lysosomal Degradation of IRF3.
    Zhang J; Wu XM; Hu YW; Chang MX
    Front Immunol; 2020; 11():580864. PubMed ID: 33101307
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein phosphatase PP1 negatively regulates the Toll-like receptor- and RIG-I-like receptor-triggered production of type I interferon by inhibiting IRF3 phosphorylation at serines 396 and 385 in macrophage.
    Gu M; Zhang T; lin W; Liu Z; Lai R; Xia D; Huang H; Wang X
    Cell Signal; 2014 Dec; 26(12):2930-9. PubMed ID: 25239187
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7.
    Unterholzner L; Sumner RP; Baran M; Ren H; Mansur DS; Bourke NM; Randow F; Smith GL; Bowie AG
    PLoS Pathog; 2011 Sep; 7(9):e1002247. PubMed ID: 21931555
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Suppression of Type I Interferon Production by Human T-Cell Leukemia Virus Type 1 Oncoprotein Tax through Inhibition of IRF3 Phosphorylation.
    Yuen CK; Chan CP; Fung SY; Wang PH; Wong WM; Tang HV; Yuen KS; Chan CP; Jin DY; Kok KH
    J Virol; 2016 Apr; 90(8):3902-3912. PubMed ID: 26819312
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TANK-Binding Kinase 1 (TBK1) Isoforms Negatively Regulate Type I Interferon Induction by Inhibiting TBK1-IRF3 Interaction and IRF3 Phosphorylation.
    Hu YW; Zhang J; Wu XM; Cao L; Nie P; Chang MX
    Front Immunol; 2018; 9():84. PubMed ID: 29441066
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DDX5 inhibits type I IFN production by promoting degradation of TBK1 and disrupting formation of TBK1 - TRAF3 complex.
    Zhang Y; Cen J; Yuan G; Jia Z; Chen K; Gao W; Chen J; Adamek M; Jia Z; Zou J
    Cell Mol Life Sci; 2023 Jul; 80(8):212. PubMed ID: 37462751
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dengue Virus NS Proteins Inhibit RIG-I/MAVS Signaling by Blocking TBK1/IRF3 Phosphorylation: Dengue Virus Serotype 1 NS4A Is a Unique Interferon-Regulating Virulence Determinant.
    Dalrymple NA; Cimica V; Mackow ER
    mBio; 2015 May; 6(3):e00553-15. PubMed ID: 25968648
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DDX3 directly facilitates IKKα activation and regulates downstream signalling pathways.
    Fullam A; Gu L; Höhn Y; Schröder M
    Biochem J; 2018 Nov; 475(22):3595-3607. PubMed ID: 30341167
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon.
    Civas A; Génin P; Morin P; Lin R; Hiscott J
    J Biol Chem; 2006 Feb; 281(8):4856-66. PubMed ID: 16380379
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MAP4-regulated dynein-dependent trafficking of BTN3A1 controls the TBK1-IRF3 signaling axis.
    Seo M; Lee SO; Kim JH; Hong Y; Kim S; Kim Y; Min DH; Kong YY; Shin J; Ahn K
    Proc Natl Acad Sci U S A; 2016 Dec; 113(50):14390-14395. PubMed ID: 27911820
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.