254 related articles for article (PubMed ID: 30699938)
1. Targeting Hedgehog Signalling through the Ubiquitylation Process: The Multiple Roles of the HECT-E3 Ligase Itch.
Infante P; Lospinoso Severini L; Bernardi F; Bufalieri F; Di Marcotullio L
Cells; 2019 Jan; 8(2):. PubMed ID: 30699938
[TBL] [Abstract][Full Text] [Related]
2. Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
Infante P; Faedda R; Bernardi F; Bufalieri F; Lospinoso Severini L; Alfonsi R; Mazzà D; Siler M; Coni S; Po A; Petroni M; Ferretti E; Mori M; De Smaele E; Canettieri G; Capalbo C; Maroder M; Screpanti I; Kool M; Pfister SM; Guardavaccaro D; Gulino A; Di Marcotullio L
Nat Commun; 2018 Mar; 9(1):976. PubMed ID: 29515120
[TBL] [Abstract][Full Text] [Related]
3. Hedgehog/Gli control by ubiquitination/acetylation interplay.
Gulino A; Di Marcotullio L; Canettieri G; De Smaele E; Screpanti I
Vitam Horm; 2012; 88():211-27. PubMed ID: 22391305
[TBL] [Abstract][Full Text] [Related]
4. Multiple ubiquitin-dependent processing pathways regulate hedgehog/gli signaling: implications for cell development and tumorigenesis.
Di Marcotullio L; Ferretti E; Greco A; De Smaele E; Screpanti I; Gulino A
Cell Cycle; 2007 Feb; 6(4):390-3. PubMed ID: 17312394
[TBL] [Abstract][Full Text] [Related]
5. MEP50/PRMT5-mediated methylation activates GLI1 in Hedgehog signalling through inhibition of ubiquitination by the ITCH/NUMB complex.
Abe Y; Suzuki Y; Kawamura K; Tanaka N
Commun Biol; 2019; 2():23. PubMed ID: 30675521
[TBL] [Abstract][Full Text] [Related]
6. The E3 ligase Itch in immune regulation and beyond.
Aki D; Zhang W; Liu YC
Immunol Rev; 2015 Jul; 266(1):6-26. PubMed ID: 26085204
[TBL] [Abstract][Full Text] [Related]
7. Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal.
Di Marcotullio L; Greco A; Mazzà D; Canettieri G; Pietrosanti L; Infante P; Coni S; Moretti M; De Smaele E; Ferretti E; Screpanti I; Gulino A
Oncogene; 2011 Jan; 30(1):65-76. PubMed ID: 20818436
[TBL] [Abstract][Full Text] [Related]
8. E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation.
Jiang W; Yao X; Shan Z; Li W; Gao Y; Zhang Q
J Mol Cell Biol; 2019 Sep; 11(9):791-803. PubMed ID: 30925584
[TBL] [Abstract][Full Text] [Related]
9. Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases.
Brigui A; Hofmann L; Argüelles C; Sanial M; Holmgren RA; Plessis A
Open Biol; 2015 Oct; 5(10):. PubMed ID: 26446620
[TBL] [Abstract][Full Text] [Related]
10. Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.
Chen XL; Chinchilla P; Fombonne J; Ho L; Guix C; Keen JH; Mehlen P; Riobo NA
Mol Cell Biol; 2014 Oct; 34(20):3855-66. PubMed ID: 25092867
[TBL] [Abstract][Full Text] [Related]
11. The Role of HECT-Type E3 Ligase in the Development of Cardiac Disease.
Goto J; Otaki Y; Watanabe T; Watanabe M
Int J Mol Sci; 2021 Jun; 22(11):. PubMed ID: 34199773
[TBL] [Abstract][Full Text] [Related]
12. Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.
Di Marcotullio L; Ferretti E; Greco A; De Smaele E; Po A; Sico MA; Alimandi M; Giannini G; Maroder M; Screpanti I; Gulino A
Nat Cell Biol; 2006 Dec; 8(12):1415-23. PubMed ID: 17115028
[TBL] [Abstract][Full Text] [Related]
13. Feedback regulation of ubiquitination and phase separation of HECT E3 ligases.
Li J; Zhu K; Gu A; Zhang Y; Huang S; Hu R; Hu W; Lei QY; Wen W
Proc Natl Acad Sci U S A; 2023 Aug; 120(33):e2302478120. PubMed ID: 37549262
[TBL] [Abstract][Full Text] [Related]
14. Lithium Suppresses Hedgehog Signaling via Promoting ITCH E3 Ligase Activity and Gli1-SUFU Interaction in PDA Cells.
Wang X; Fang Z; Wang A; Luo C; Cheng X; Lu M
Front Pharmacol; 2017; 8():820. PubMed ID: 29249966
[TBL] [Abstract][Full Text] [Related]
15. HECT E3 ubiquitin ligases - emerging insights into their biological roles and disease relevance.
Wang Y; Argiles-Castillo D; Kane EI; Zhou A; Spratt DE
J Cell Sci; 2020 Apr; 133(7):. PubMed ID: 32265230
[TBL] [Abstract][Full Text] [Related]
16. Regulation of Smoothened ubiquitylation and cell surface expression through a Cul4-DDB1-Gβ E3 ubiquitin ligase complex.
Li S; Cho YS; Wang B; Li S; Jiang J
J Cell Sci; 2018 Aug; 131(15):. PubMed ID: 29930086
[TBL] [Abstract][Full Text] [Related]
17. SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.
Raducu M; Fung E; Serres S; Infante P; Barberis A; Fischer R; Bristow C; Thézénas ML; Finta C; Christianson JC; Buffa FM; Kessler BM; Sibson NR; Di Marcotullio L; Toftgård R; D'Angiolella V
EMBO J; 2016 Jul; 35(13):1400-16. PubMed ID: 27234298
[TBL] [Abstract][Full Text] [Related]
18. Hedgehog reciprocally controls trafficking of Smo and Ptc through the Smurf family of E3 ubiquitin ligases.
Li S; Li S; Wang B; Jiang J
Sci Signal; 2018 Feb; 11(516):. PubMed ID: 29438012
[TBL] [Abstract][Full Text] [Related]
19. High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy.
Rossi M; Rotblat B; Ansell K; Amelio I; Caraglia M; Misso G; Bernassola F; Cavasotto CN; Knight RA; Ciechanover A; Melino G
Cell Death Dis; 2014 May; 5(5):e1203. PubMed ID: 24787015
[TBL] [Abstract][Full Text] [Related]
20. MAVS Ubiquitylation: Function, Mechanism, and Beyond.
Dong H; Shen J
Front Biosci (Landmark Ed); 2024 Feb; 29(2):72. PubMed ID: 38420830
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]