BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 30700419)

  • 1. Phylogenetic and functional analysis of ADAMTS13 identifies highly conserved domains essential for allosteric regulation.
    Muia J; Zhu J; Greco SC; Vanhoorelbeke K; Gupta G; Westfield LA; Sadler JE
    Blood; 2019 Apr; 133(17):1899-1908. PubMed ID: 30700419
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exploring the "minimal" structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering.
    Zhu J; Muia J; Gupta G; Westfield LA; Vanhoorelbeke K; Tolia NH; Sadler JE
    Blood; 2019 Apr; 133(17):1909-1918. PubMed ID: 30692120
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allosteric activation of ADAMTS13 by von Willebrand factor.
    Muia J; Zhu J; Gupta G; Haberichter SL; Friedman KD; Feys HB; Deforche L; Vanhoorelbeke K; Westfield LA; Roth R; Tolia NH; Heuser JE; Sadler JE
    Proc Natl Acad Sci U S A; 2014 Dec; 111(52):18584-9. PubMed ID: 25512528
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure and substrate-induced activation of ADAMTS13.
    Petri A; Kim HJ; Xu Y; de Groot R; Li C; Vandenbulcke A; Vanhoorelbeke K; Emsley J; Crawley JTB
    Nat Commun; 2019 Aug; 10(1):3781. PubMed ID: 31439947
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease.
    Gao W; Anderson PJ; Majerus EM; Tuley EA; Sadler JE
    Proc Natl Acad Sci U S A; 2006 Dec; 103(50):19099-104. PubMed ID: 17146059
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor.
    South K; Freitas MO; Lane DA
    J Biol Chem; 2017 Apr; 292(14):5760-5769. PubMed ID: 28209710
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13).
    Xiang Y; de Groot R; Crawley JT; Lane DA
    Proc Natl Acad Sci U S A; 2011 Jul; 108(28):11602-7. PubMed ID: 21705658
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antibodies that conformationally activate ADAMTS13 allosterically enhance metalloprotease domain function.
    Schelpe AS; Petri A; Roose E; Pareyn I; Deckmyn H; De Meyer SF; Crawley JTB; Vanhoorelbeke K
    Blood Adv; 2020 Mar; 4(6):1072-1080. PubMed ID: 32196558
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of cysteine thiol-based linkages in ADAMTS13 in support of a non-proteolytic regulation of von Willebrand factor.
    Rottensteiner H; Seyfried BK; Kaufmann S; Fiedler C; Dong JF; Zheng XL; Plaimauer B; Scheiflinger F
    J Thromb Haemost; 2019 Dec; 17(12):2099-2109. PubMed ID: 31393047
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Binding of platelet glycoprotein Ibalpha to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13.
    Nishio K; Anderson PJ; Zheng XL; Sadler JE
    Proc Natl Acad Sci U S A; 2004 Jul; 101(29):10578-83. PubMed ID: 15249683
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13.
    Zheng X; Nishio K; Majerus EM; Sadler JE
    J Biol Chem; 2003 Aug; 278(32):30136-41. PubMed ID: 12791682
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions.
    Tao Z; Peng Y; Nolasco L; Cal S; Lopez-Otin C; Li R; Moake JL; López JA; Dong JF
    Blood; 2005 Dec; 106(13):4139-45. PubMed ID: 16141351
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [ADAMTS13-Mediated Proteolytic Cleavage of Unusually Large von Willebrand Factor Polymers on Endothelial Cells in the Absence of Fluid Shear Stress].
    Zhao SC; Li H; Wang M; Zhao YH; Li XJ; Jin SY
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2024 Apr; 32(2):532-540. PubMed ID: 38660863
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interplay between ADAMTS13 and von Willebrand factor in inherited and acquired thrombotic microangiopathies.
    Soejima K; Nakagaki T
    Semin Hematol; 2005 Jan; 42(1):56-62. PubMed ID: 15662617
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor.
    Ai J; Smith P; Wang S; Zhang P; Zheng XL
    J Biol Chem; 2005 Aug; 280(33):29428-34. PubMed ID: 15975930
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thrombospondin-1 and ADAMTS13 competitively bind to VWF A2 and A3 domains in vitro.
    Wang A; Liu F; Dong N; Ma Z; Zhang J; Su J; Zhao Y; Ruan C
    Thromb Res; 2010 Oct; 126(4):e260-5. PubMed ID: 20705333
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rearranging exosites in noncatalytic domains can redirect the substrate specificity of ADAMTS proteases.
    Gao W; Zhu J; Westfield LA; Tuley EA; Anderson PJ; Sadler JE
    J Biol Chem; 2012 Aug; 287(32):26944-52. PubMed ID: 22707719
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The distal carboxyterminal domains of murine ADAMTS13 influence proteolysis of platelet-decorated VWF strings in vivo.
    De Maeyer B; De Meyer SF; Feys HB; Pareyn I; Vandeputte N; Deckmyn H; Vanhoorelbeke K
    J Thromb Haemost; 2010 Oct; 8(10):2305-12. PubMed ID: 20695979
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Domain-specific mechanical modulation of VWF-ADAMTS13 interaction.
    Li Z; Lin J; Sulchek T; Cruz MA; Wu J; Dong JF; Zhu C
    Mol Biol Cell; 2019 Jul; 30(16):1920-1929. PubMed ID: 31067148
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proteolytic processing of von Willebrand factor by adamts13 and leukocyte proteases.
    Lancellotti S; Basso M; De Cristofaro R
    Mediterr J Hematol Infect Dis; 2013 Sep; 5(1):e2013058. PubMed ID: 24106608
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.