These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 30703487)

  • 1. Allosteric small molecule modulators of nuclear receptors.
    Meijer FA; Leijten-van de Gevel IA; de Vries RMJM; Brunsveld L
    Mol Cell Endocrinol; 2019 Apr; 485():20-34. PubMed ID: 30703487
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting Nuclear Receptors with PROTAC degraders.
    Flanagan JJ; Neklesa TK
    Mol Cell Endocrinol; 2019 Aug; 493():110452. PubMed ID: 31125586
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Delineation of the molecular determinants of the unique allosteric binding site of the orphan nuclear receptor RORγt.
    Leijten-van de Gevel IA; Brunsveld L
    J Biol Chem; 2020 Jul; 295(27):9183-9191. PubMed ID: 32439807
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Non-canonical modulators of nuclear receptors.
    Tice CM; Zheng YJ
    Bioorg Med Chem Lett; 2016 Sep; 26(17):4157-64. PubMed ID: 27503683
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Allosteric targeting of receptor tyrosine kinases.
    De Smet F; Christopoulos A; Carmeliet P
    Nat Biotechnol; 2014 Nov; 32(11):1113-20. PubMed ID: 25380447
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Allosteric Binding Sites On Nuclear Receptors: Focus On Drug Efficacy and Selectivity.
    Fischer A; Smieško M
    Int J Mol Sci; 2020 Jan; 21(2):. PubMed ID: 31947677
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel Allosteric Modulators of G Protein-coupled Receptors.
    Gentry PR; Sexton PM; Christopoulos A
    J Biol Chem; 2015 Aug; 290(32):19478-88. PubMed ID: 26100627
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Small-Molecule Positive Allosteric Modulators of the
    Ahn S; Pani B; Kahsai AW; Olsen EK; Husemoen G; Vestergaard M; Jin L; Zhao S; Wingler LM; Rambarat PK; Simhal RK; Xu TT; Sun LD; Shim PJ; Staus DP; Huang LY; Franch T; Chen X; Lefkowitz RJ
    Mol Pharmacol; 2018 Aug; 94(2):850-861. PubMed ID: 29769246
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A conserved surface on the ligand binding domain of nuclear receptors for allosteric control.
    Buzón V; Carbó LR; Estruch SB; Fletterick RJ; Estébanez-Perpiñá E
    Mol Cell Endocrinol; 2012 Jan; 348(2):394-402. PubMed ID: 21878368
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Allosteric Modulators of the Class A G Protein Coupled Receptors.
    Tschammer N
    Adv Exp Med Biol; 2016; 917():185-207. PubMed ID: 27236557
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Beyond the ligand-binding pocket: targeting alternate sites in nuclear receptors.
    Caboni L; Lloyd DG
    Med Res Rev; 2013 Sep; 33(5):1081-118. PubMed ID: 23344935
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Allosteric mechanisms of nuclear receptors: insights from computational simulations.
    Mackinnon JA; Gallastegui N; Osguthorpe DJ; Hagler AT; Estébanez-Perpiñá E
    Mol Cell Endocrinol; 2014 Aug; 393(1-2):75-82. PubMed ID: 24911885
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Retinoid and Non-Retinoid Ligands of the Rod Visual G Protein-Coupled Receptor.
    Ortega JT; Jastrzebska B
    Int J Mol Sci; 2019 Dec; 20(24):. PubMed ID: 31835521
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs).
    Moore TW; Mayne CG; Katzenellenbogen JA
    Mol Endocrinol; 2010 Apr; 24(4):683-95. PubMed ID: 19933380
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intracellular Receptor Modulation: Novel Approach to Target GPCRs.
    Ortiz Zacarías NV; Lenselink EB; IJzerman AP; Handel TM; Heitman LH
    Trends Pharmacol Sci; 2018 Jun; 39(6):547-559. PubMed ID: 29653834
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric modulation as a unifying mechanism for receptor function and regulation.
    Changeux JP; Christopoulos A
    Diabetes Obes Metab; 2017 Sep; 19 Suppl 1():4-21. PubMed ID: 28880476
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of nuclear receptor function: Targeting the protein-DNA interface.
    Veras Ribeiro Filho H; Tambones IL; Mariano Gonçalves Dias M; Bernardi Videira N; Bruder M; Amorim Amato A; Migliorini Figueira AC
    Mol Cell Endocrinol; 2019 Mar; 484():1-14. PubMed ID: 30703486
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein Allostery and Ligand Design: Computational Design Meets Experiments to Discover Novel Chemical Probes.
    Triveri A; Sanchez-Martin C; Torielli L; Serapian SA; Marchetti F; D'Acerno G; Pirota V; Castelli M; Moroni E; Ferraro M; Quadrelli P; Rasola A; Colombo G
    J Mol Biol; 2022 Sep; 434(17):167468. PubMed ID: 35101454
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs.
    Bartuzi D; Kaczor AA; Matosiuk D
    Methods Mol Biol; 2018; 1705():297-319. PubMed ID: 29188568
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Large-Scale Screening of Per- and Polyfluoroalkyl Substance Binding Interactions and Their Mixtures with Nuclear Receptors.
    Roy S; Moran J; Danasekaran K; O'Brien K; Dakshanamurthy S
    Int J Mol Sci; 2024 Jul; 25(15):. PubMed ID: 39125814
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.