BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 30707489)

  • 1. Discovery of Small-Molecule Antibiotics against a Unique tRNA-Mediated Regulation of Transcription in Gram-Positive Bacteria.
    Frohlich KM; Weintraub SF; Bell JT; Todd GC; Väre VYP; Schneider R; Kloos ZA; Tabe ES; Cantara WA; Stark CJ; Onwuanaibe UJ; Duffy BC; Basanta-Sanchez M; Kitchen DB; McDonough KA; Agris PF
    ChemMedChem; 2019 Apr; 14(7):758-769. PubMed ID: 30707489
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small-Molecule Antibiotics Inhibiting tRNA-Regulated Gene Expression Is a Viable Strategy for Targeting Gram-Positive Bacteria.
    Väre VYP; Schneider RF; Kim H; Lasek-Nesselquist E; McDonough KA; Agris PF
    Antimicrob Agents Chemother; 2020 Dec; 65(1):. PubMed ID: 33077662
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Direct modulation of T-box riboswitch-controlled transcription by protein synthesis inhibitors.
    Stamatopoulou V; Apostolidi M; Li S; Lamprinou K; Papakyriakou A; Zhang J; Stathopoulos C
    Nucleic Acids Res; 2017 Sep; 45(17):10242-10258. PubMed ID: 28973457
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of Methionyl-tRNA Synthetase Inhibitors as Antibiotics for Gram-Positive Bacterial Infections.
    Faghih O; Zhang Z; Ranade RM; Gillespie JR; Creason SA; Huang W; Shibata S; Barros-Álvarez X; Verlinde CLMJ; Hol WGJ; Fan E; Buckner FS
    Antimicrob Agents Chemother; 2017 Nov; 61(11):. PubMed ID: 28848016
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antioxidant activity and antibacterial evaluation of new thiazolin-4-one derivatives as potential tryptophanyl-tRNA synthetase inhibitors.
    Stana A; Vodnar DC; Marc G; Benedec D; Tiperciuc B; Tamaian R; Oniga O
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):898-908. PubMed ID: 30938216
    [TBL] [Abstract][Full Text] [Related]  

  • 6. tRNA regulation of gene expression: interactions of an mRNA 5'-UTR with a regulatory tRNA.
    Nelson AR; Henkin TM; Agris PF
    RNA; 2006 Jul; 12(7):1254-61. PubMed ID: 16741230
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aminoacyl-tRNA synthetase inhibitors as potent antibacterials.
    Lv PC; Zhu HL
    Curr Med Chem; 2012; 19(21):3550-63. PubMed ID: 22680640
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RNA drug discovery: Conformational restriction enhances specific modulation of the T-box riboswitch function.
    Armstrong I; Aldhumani AH; Schopis JL; Fang F; Parsons E; Zeng C; Hossain MI; Bergmeier SC; Hines JV
    Bioorg Med Chem; 2020 Oct; 28(20):115696. PubMed ID: 33069065
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, molecular docking and biological evaluation of metronidazole derivatives containing piperazine skeleton as potential antibacterial agents.
    Wang SF; Yin Y; Qiao F; Wu X; Sha S; Zhang L; Zhu HL
    Bioorg Med Chem; 2014 Apr; 22(8):2409-15. PubMed ID: 24680059
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A New Promising Anti-Infective Agent Inhibits Biofilm Growth by Targeting Simultaneously a Conserved RNA Function That Controls Multiple Genes.
    Seyler TM; Moore C; Kim H; Ramachandran S; Agris PF
    Antibiotics (Basel); 2021 Jan; 10(1):. PubMed ID: 33406640
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and molecular docking of salicylic acid derivatives containing metronidazole as a new class of antimicrobial agents.
    Guo ZH; Yin Y; Wang C; Wang PF; Zhang XT; Wang ZC; Zhu HL
    Bioorg Med Chem; 2015 Sep; 23(18):6148-56. PubMed ID: 26304108
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tyrosyl-tRNA synthetase inhibitors as antibacterial agents: synthesis, molecular docking and structure-activity relationship analysis of 3-aryl-4-arylaminofuran-2(5H)-ones.
    Xiao ZP; Ma TW; Liao ML; Feng YT; Peng XC; Li JL; Li ZP; Wu Y; Luo Q; Deng Y; Liang X; Zhu HL
    Eur J Med Chem; 2011 Oct; 46(10):4904-14. PubMed ID: 21856050
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lysyl-tRNA Synthetase from
    Balboa S; Hu Y; Dean FB; Bullard JM
    SLAS Discov; 2020 Jan; 25(1):57-69. PubMed ID: 31498734
    [No Abstract]   [Full Text] [Related]  

  • 14. Two Forms of Tyrosyl-tRNA Synthetase from
    Hughes CA; Gorabi V; Escamilla Y; Dean FB; Bullard JM
    SLAS Discov; 2020 Oct; 25(9):1072-1086. PubMed ID: 32583746
    [No Abstract]   [Full Text] [Related]  

  • 15. Synthesis and evaluation of new tyrosyl-tRNA synthetase inhibitors as antibacterial agents based on a N2-(arylacetyl)glycinanilide scaffold.
    Xiao ZP; Wei W; Wang PF; Shi WK; Zhu N; Xie MQ; Sun YW; Li LX; Xie YX; Zhu LS; Tang N; Ouyang H; Li XH; Wang GC; Zhu HL
    Eur J Med Chem; 2015 Sep; 102():631-8. PubMed ID: 26318069
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The T box mechanism: tRNA as a regulatory molecule.
    Green NJ; Grundy FJ; Henkin TM
    FEBS Lett; 2010 Jan; 584(2):318-24. PubMed ID: 19932103
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 1,1'-Carbonyldiimidazole (CDI) Mediated Facile Synthesis, Structural Characterization, Antimicrobial Activity, and in-silico Studies of Coumarin- 3-carboxamide Derivatives.
    Salar U; Khan KM; Fakhri MI; Hussain S; Tauseef S; Ameer S; Wadood A; Khan H; Perveen S
    Med Chem; 2018; 14(1):86-101. PubMed ID: 28641525
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conservation of a transcription antitermination mechanism in aminoacyl-tRNA synthetase and amino acid biosynthesis genes in gram-positive bacteria.
    Grundy FJ; Henkin TM
    J Mol Biol; 1994 Jan; 235(2):798-804. PubMed ID: 8289305
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Investigation of antibiotic and antibacterial agent cross-resistance in target bacteria from homes of antibacterial product users and nonusers.
    Cole EC; Addison RM; Rubino JR; Leese KE; Dulaney PD; Newell MS; Wilkins J; Gaber DJ; Wineinger T; Criger DA
    J Appl Microbiol; 2003; 95(4):664-76. PubMed ID: 12969278
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antibacterial Small Molecules That Potently Inhibit Staphylococcus aureus Lipoteichoic Acid Biosynthesis.
    Naclerio GA; Karanja CW; Opoku-Temeng C; Sintim HO
    ChemMedChem; 2019 May; 14(10):1000-1004. PubMed ID: 30939229
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.