BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

394 related articles for article (PubMed ID: 30711829)

  • 1. Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors.
    Li X; Xu Q; Li C; Luo J; Li X; Wang L; Jiang B; Shi D
    Eur J Med Chem; 2019 Mar; 166():178-185. PubMed ID: 30711829
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2',3,3'-Tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice.
    Li C; Luo J; Guo S; Jia X; Guo C; Li X; Xu Q; Shi D
    Mol Pharm; 2019 May; 16(5):1839-1850. PubMed ID: 30974944
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes.
    Xu Q; Luo J; Wu N; Zhang R; Shi D
    Int J Biol Macromol; 2018 Jan; 106():379-386. PubMed ID: 28811203
    [TBL] [Abstract][Full Text] [Related]  

  • 4. α-Methyl artoflavanocoumarin from Juniperus chinensis exerts anti-diabetic effects by inhibiting PTP1B and activating the PI3K/Akt signaling pathway in insulin-resistant HepG2 cells.
    Jung HJ; Seong SH; Ali MY; Min BS; Jung HA; Choi JS
    Arch Pharm Res; 2017 Dec; 40(12):1403-1413. PubMed ID: 29177868
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors.
    Zhang R; Yu R; Xu Q; Li X; Luo J; Jiang B; Wang L; Guo S; Wu N; Shi D
    Eur J Med Chem; 2017 Jul; 134():24-33. PubMed ID: 28395151
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Magnolia officinalis Extract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice.
    Sun J; Wang Y; Fu X; Chen Y; Wang D; Li W; Xing S; Li G
    Biomed Res Int; 2015; 2015():139451. PubMed ID: 26064877
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trivaric acid, a new inhibitor of PTP1b with potent beneficial effect on diabetes.
    Sun W; Zhang B; Zheng H; Zhuang C; Li X; Lu X; Quan C; Dong Y; Zheng Z; Xiu Z
    Life Sci; 2017 Jan; 169():52-64. PubMed ID: 27871946
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Therapeutic effects of the allosteric protein tyrosine phosphatase 1B inhibitor KY-226 on experimental diabetes and obesity via enhancements in insulin and leptin signaling in mice.
    Ito Y; Fukui M; Kanda M; Morishita K; Shoji Y; Kitao T; Hinoi E; Shirahase H
    J Pharmacol Sci; 2018 May; 137(1):38-46. PubMed ID: 29731242
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B.
    Li XQ; Xu Q; Luo J; Wang LJ; Jiang B; Zhang RS; Shi DY
    Eur J Med Chem; 2017 Aug; 136():348-359. PubMed ID: 28511130
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A potent, selective, and orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models.
    Krishnan N; Konidaris KF; Gasser G; Tonks NK
    J Biol Chem; 2018 Feb; 293(5):1517-1525. PubMed ID: 29217773
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of novel PTP1B inhibitors by pharmacophore based virtual screening, scaffold hopping and docking.
    Balaramnavar VM; Srivastava R; Rahuja N; Gupta S; Rawat AK; Varshney S; Chandasana H; Chhonker YS; Doharey PK; Kumar S; Gautam S; Srivastava SP; Bhatta RS; Saxena JK; Gaikwad AN; Srivastava AK; Saxena AK
    Eur J Med Chem; 2014 Nov; 87():578-94. PubMed ID: 25299681
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Potential Inhibitors of Protein Tyrosine Phosphatase (PTP1B) Enzyme: Promising Target for Type-II Diabetes Mellitus.
    Nandi S; Saxena M
    Curr Top Med Chem; 2020; 20(29):2692-2707. PubMed ID: 32888269
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity.
    Liu P; Du Y; Song L; Shen J; Li Q
    Eur J Med Chem; 2016 Aug; 118():27-33. PubMed ID: 27123900
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study.
    Luo J; Zhang R; Wang X; Hou Z; Guo S; Jiang B
    Int J Biol Macromol; 2020 Nov; 163():200-208. PubMed ID: 32619661
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional properties of Claramine: a novel PTP1B inhibitor and insulin-mimetic compound.
    Qin Z; Pandey NR; Zhou X; Stewart CA; Hari A; Huang H; Stewart AF; Brunel JM; Chen HH
    Biochem Biophys Res Commun; 2015 Feb; 458(1):21-7. PubMed ID: 25623533
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Role of protein tyrosine phosphatase 1B in the type 2 diabetes and obesity].
    Wang C; Wang L; Yang Z
    Yi Chuan; 2004 Nov; 26(6):941-6. PubMed ID: 15640130
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties.
    Jiang B; Luo J; Guo S; Wang L
    Bioorg Chem; 2021 Mar; 108():104648. PubMed ID: 33493928
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoglycemic effect and mechanism of honokiol on type 2 diabetic mice.
    Sun J; Fu X; Liu Y; Wang Y; Huo B; Guo Y; Gao X; Li W; Hu X
    Drug Des Devel Ther; 2015; 9():6327-42. PubMed ID: 26674084
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fumosorinone, a novel PTP1B inhibitor, activates insulin signaling in insulin-resistance HepG2 cells and shows anti-diabetic effect in diabetic KKAy mice.
    Liu ZQ; Liu T; Chen C; Li MY; Wang ZY; Chen RS; Wei GX; Wang XY; Luo DQ
    Toxicol Appl Pharmacol; 2015 May; 285(1):61-70. PubMed ID: 25796170
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyrazoles as novel protein tyrosine phosphatase 1B (PTP1B) inhibitors: An in vitro and in silico study.
    Rocha S; Lucas M; Silva VLM; Gomes PMO; Silva AMS; Araújo AN; Aniceto N; Guedes RC; Corvo ML; Fernandes E; Freitas M
    Int J Biol Macromol; 2021 Jun; 181():1171-1182. PubMed ID: 33857515
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.