BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

403 related articles for article (PubMed ID: 30715997)

  • 21. Stand up to cancer phase Ib study of pan-phosphoinositide-3-kinase inhibitor buparlisib with letrozole in estrogen receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer.
    Mayer IA; Abramson VG; Isakoff SJ; Forero A; Balko JM; Kuba MG; Sanders ME; Yap JT; Van den Abbeele AD; Li Y; Cantley LC; Winer E; Arteaga CL
    J Clin Oncol; 2014 Apr; 32(12):1202-9. PubMed ID: 24663045
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Buparlisib plus fulvestrant versus placebo plus fulvestrant for postmenopausal, hormone receptor-positive, human epidermal growth factor receptor 2-negative, advanced breast cancer: Overall survival results from BELLE-2.
    Campone M; Im SA; Iwata H; Clemons M; Ito Y; Awada A; Chia S; Jagiełło-Gruszfeld A; Pistilli B; Tseng LM; Hurvitz S; Masuda N; Cortés J; De Laurentiis M; Arteaga CL; Jiang Z; Jonat W; Le Mouhaër S; Sankaran B; Bourdeau L; El-Hashimy M; Sellami D; Baselga J
    Eur J Cancer; 2018 Nov; 103():147-154. PubMed ID: 30241001
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Buparlisib plus carboplatin or lomustine in patients with recurrent glioblastoma: a phase Ib/II, open-label, multicentre, randomised study.
    Rosenthal M; Clement PM; Campone M; Gil-Gil MJ; DeGroot J; Chinot O; Idbaih A; Gan H; Raizer J; Wen PY; Pineda E; Donnet V; Mills D; El-Hashimy M; Mason W
    ESMO Open; 2020 Jul; 5(4):. PubMed ID: 32665311
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Phase I, open-label, multicentre study of buparlisib in combination with temozolomide or with concomitant radiation therapy and temozolomide in patients with newly diagnosed glioblastoma.
    Wen PY; Rodon JA; Mason W; Beck JT; DeGroot J; Donnet V; Mills D; El-Hashimy M; Rosenthal M
    ESMO Open; 2020 Jul; 5(4):. PubMed ID: 32661186
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Safety and Efficacy of Buparlisib (BKM120) in Patients with PI3K Pathway-Activated Non-Small Cell Lung Cancer: Results from the Phase II BASALT-1 Study.
    Vansteenkiste JF; Canon JL; De Braud F; Grossi F; De Pas T; Gray JE; Su WC; Felip E; Yoshioka H; Gridelli C; Dy GK; Thongprasert S; Reck M; Aimone P; Vidam GA; Roussou P; Wang YA; Di Tomaso E; Soria JC
    J Thorac Oncol; 2015 Sep; 10(9):1319-1327. PubMed ID: 26098748
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Parallel phase Ib studies of two schedules of buparlisib (BKM120) plus carboplatin and paclitaxel (q21 days or q28 days) for patients with advanced solid tumors.
    Hyman DM; Snyder AE; Carvajal RD; Gerecitano JF; Voss MH; Ho AL; Konner J; Winkelmann JL; Stasi MA; Monson KR; Iasonos A; Spriggs DR; Bialer P; Lacouture ME; Teitcher JB; Katabi N; Fury MG
    Cancer Chemother Pharmacol; 2015 Apr; 75(4):747-55. PubMed ID: 25672916
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma.
    McGowan DR; Skwarski M; Bradley KM; Campo L; Fenwick JD; Gleeson FV; Green M; Horne A; Maughan TS; McCole MG; Mohammed S; Muschel RJ; Ng SM; Panakis N; Prevo R; Strauss VY; Stuart R; Tacconi EMC; Vallis KA; McKenna WG; Macpherson RE; Higgins GS
    Eur J Cancer; 2019 May; 113():87-95. PubMed ID: 30991262
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Phase I dose-escalation and -expansion study of buparlisib (BKM120), an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors.
    Rodon J; Braña I; Siu LL; De Jonge MJ; Homji N; Mills D; Di Tomaso E; Sarr C; Trandafir L; Massacesi C; Eskens F; Bendell JC
    Invest New Drugs; 2014 Aug; 32(4):670-81. PubMed ID: 24652201
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Phase II study of the PI3K inhibitor BKM120 in patients with advanced or recurrent endometrial carcinoma: a stratified type I-type II study from the GINECO group.
    Heudel PE; Fabbro M; Roemer-Becuwe C; Kaminsky MC; Arnaud A; Joly F; Roche-Forestier S; Meunier J; Foa C; You B; Priou F; Tazi Y; Floquet A; Selle F; Berton-Rigaud D; Lesoin A; Kalbacher E; Lortholary A; Favier L; Treilleux I; Ray-Coquard I
    Br J Cancer; 2017 Jan; 116(3):303-309. PubMed ID: 28072765
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Buparlisib in breast cancer.
    Sirohi B; Rastogi S; Dawood S
    Future Oncol; 2015; 11(10):1463-70. PubMed ID: 25963424
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A phase 1b dose expansion study of the pan-class I PI3K inhibitor buparlisib (BKM120) plus carboplatin and paclitaxel in PTEN deficient tumors and with dose intensified carboplatin and paclitaxel.
    Smyth LM; Monson KR; Jhaveri K; Drilon A; Li BT; Abida W; Iyer G; Gerecitano JF; Gounder M; Harding JJ; Voss MH; Makker V; Ho AL; Razavi P; Iasonos A; Bialer P; Lacouture ME; Teitcher JB; Erinjeri JP; Katabi N; Fury MG; Hyman DM
    Invest New Drugs; 2017 Dec; 35(6):742-750. PubMed ID: 28281183
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A phase Ib dose-escalation study of the oral pan-PI3K inhibitor buparlisib (BKM120) in combination with the oral MEK1/2 inhibitor trametinib (GSK1120212) in patients with selected advanced solid tumors.
    Bedard PL; Tabernero J; Janku F; Wainberg ZA; Paz-Ares L; Vansteenkiste J; Van Cutsem E; Pérez-García J; Stathis A; Britten CD; Le N; Carter K; Demanse D; Csonka D; Peters M; Zubel A; Nauwelaerts H; Sessa C
    Clin Cancer Res; 2015 Feb; 21(4):730-8. PubMed ID: 25500057
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Buparlisib is a brain penetrable pan-PI3K inhibitor.
    de Gooijer MC; Zhang P; Buil LCM; Çitirikkaya CH; Thota N; Beijnen JH; van Tellingen O
    Sci Rep; 2018 Jul; 8(1):10784. PubMed ID: 30018387
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Benefits versus risk profile of buparlisib for the treatment of breast cancer.
    Patsouris A; Augereau P; Frenel JS; Robert M; Gourmelon C; Bourbouloux E; Berton-Rigaud D; Chevalier LM; Campone M
    Expert Opin Drug Saf; 2019 Jul; 18(7):553-562. PubMed ID: 31159599
    [No Abstract]   [Full Text] [Related]  

  • 35. Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma.
    Batchelor TT; Duda DG; di Tomaso E; Ancukiewicz M; Plotkin SR; Gerstner E; Eichler AF; Drappatz J; Hochberg FH; Benner T; Louis DN; Cohen KS; Chea H; Exarhopoulos A; Loeffler JS; Moses MA; Ivy P; Sorensen AG; Wen PY; Jain RK
    J Clin Oncol; 2010 Jun; 28(17):2817-23. PubMed ID: 20458050
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Mouse-human co-clinical trials demonstrate superior anti-tumour effects of buparlisib (BKM120) and cetuximab combination in squamous cell carcinoma of head and neck.
    Kim HR; Kang HN; Yun MR; Ju KY; Choi JW; Jung DM; Pyo KH; Hong MH; Ahn MJ; Sun JM; Kim HS; Kim J; Yoo J; Kim KR; Koh YW; Kim SH; Choi EC; Yoon SO; Shim HS; Paik S; Kim TM; Cho BC
    Br J Cancer; 2020 Dec; 123(12):1720-1729. PubMed ID: 32963347
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A phase Ib study of a PI3Kinase inhibitor BKM120 in combination with panitumumab in patients with KRAS wild-type advanced colorectal cancer.
    Goodwin R; Jonker D; Chen E; Kennecke H; Cabanero M; Tsao MS; Vickers M; Bohemier C; Lim H; Ritter H; Tu D; Seymour L
    Invest New Drugs; 2020 Aug; 38(4):1077-1084. PubMed ID: 31506897
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The Inhibitory Response to PI3K/AKT Pathway Inhibitors MK-2206 and Buparlisib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines.
    Ma Y; Sender S; Sekora A; Kong W; Bauer P; Ameziane N; Al-Ali R; Krake S; Radefeldt M; Weiss FU; Lerch MM; Parveen A; Zechner D; Junghanss C; Murua Escobar H
    Int J Mol Sci; 2022 Apr; 23(8):. PubMed ID: 35457111
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Phase II trial of an AKT inhibitor (perifosine) for recurrent glioblastoma.
    Kaley TJ; Panageas KS; Mellinghoff IK; Nolan C; Gavrilovic IT; DeAngelis LM; Abrey LE; Holland EC; Lassman AB
    J Neurooncol; 2019 Sep; 144(2):403-407. PubMed ID: 31325145
    [TBL] [Abstract][Full Text] [Related]  

  • 40. PI3K inhibitor provides durable response in metastatic metaplastic carcinoma of the breast: A hidden gem in the BELLE-4 study.
    Yang MH; Chen IC; Lu YS
    J Formos Med Assoc; 2019 Sep; 118(9):1333-1338. PubMed ID: 30577988
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.