210 related articles for article (PubMed ID: 30725418)
1. Safety and Toxicity of Recombinant Methioninase and Polyethylene Glycol (PEG) Recombinant Methioninase in Primates.
Hoffman RM; Yang Z; Tan Y; Han Q; Li S; Yagi S
Methods Mol Biol; 2019; 1866():211-229. PubMed ID: 30725418
[TBL] [Abstract][Full Text] [Related]
2. PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates.
Yang Z; Wang J; Lu Q; Xu J; Kobayashi Y; Takakura T; Takimoto A; Yoshioka T; Lian C; Chen C; Zhang D; Zhang Y; Li S; Sun X; Tan Y; Yagi S; Frenkel EP; Hoffman RM
Cancer Res; 2004 Sep; 64(18):6673-8. PubMed ID: 15374983
[TBL] [Abstract][Full Text] [Related]
3. Development of Recombinant Methioninase for Cancer Treatment.
Hoffman RM; Tan Y; Li S; Han Q; Yagi S; Takakura T; Takimoto A; Inagaki K; Kudou D
Methods Mol Biol; 2019; 1866():107-131. PubMed ID: 30725412
[TBL] [Abstract][Full Text] [Related]
4. Circulating half-life of PEGylated recombinant methioninase holoenzyme is highly dose dependent on cofactor pyridoxal-5'-phosphate.
Yang Z; Sun X; Li S; Tan Y; Wang X; Zhang N; Yagi S; Takakura T; Kobayashi Y; Takimoto A; Yoshioka T; Suginaka A; Frenkel EP; Hoffman RM
Cancer Res; 2004 Aug; 64(16):5775-8. PubMed ID: 15313919
[TBL] [Abstract][Full Text] [Related]
5. Pharmacokinetics, methionine depletion, and antigenicity of recombinant methioninase in primates.
Yang Z; Wang J; Yoshioka T; Li B; Lu Q; Li S; Sun X; Tan Y; Yagi S; Frenkel EP; Hoffman RM
Clin Cancer Res; 2004 Mar; 10(6):2131-8. PubMed ID: 15041734
[TBL] [Abstract][Full Text] [Related]
6. In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation.
Sun X; Yang Z; Li S; Tan Y; Zhang N; Wang X; Yagi S; Yoshioka T; Takimoto A; Mitsushima K; Suginaka A; Frenkel EP; Hoffman RM
Cancer Res; 2003 Dec; 63(23):8377-83. PubMed ID: 14678999
[TBL] [Abstract][Full Text] [Related]
7. Polyethylene glycol conjugation of recombinant methioninase for cancer therapy.
Tan Y; Sun X; Xu M; An Z; Tan X; Han Q; Miljkovic DA; Yang M; Hoffman RM
Protein Expr Purif; 1998 Feb; 12(1):45-52. PubMed ID: 9473456
[TBL] [Abstract][Full Text] [Related]
8. Broad selective efficacy of recombinant methioninase and polyethylene glycol-modified recombinant methioninase on cancer cells In Vitro.
Tan Y; Xu M; Hoffman RM
Anticancer Res; 2010 Apr; 30(4):1041-6. PubMed ID: 20530407
[TBL] [Abstract][Full Text] [Related]
9. Overexpression and large-scale production of recombinant L-methionine-alpha-deamino-gamma-mercaptomethane-lyase for novel anticancer therapy.
Tan Y; Xu M; Tan X; Tan X; Wang X; Saikawa Y; Nagahama T; Sun X; Lenz M; Hoffman RM
Protein Expr Purif; 1997 Mar; 9(2):233-45. PubMed ID: 9056489
[TBL] [Abstract][Full Text] [Related]
10. Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.
Murakami T; Li S; Han Q; Tan Y; Kiyuna T; Igarashi K; Kawaguchi K; Hwang HK; Miyake K; Singh AS; Nelson SD; Dry SM; Li Y; Hiroshima Y; Lwin TM; DeLong JC; Chishima T; Tanaka K; Bouvet M; Endo I; Eilber FC; Hoffman RM
Oncotarget; 2017 May; 8(22):35630-35638. PubMed ID: 28404944
[TBL] [Abstract][Full Text] [Related]
11. Protein carboxyl amidation increases the potential extent of protein polyethylene glycol conjugation.
Li S; Yang Z; Sun X; Tan Y; Yagi S; Hoffman RM
Anal Biochem; 2004 Jul; 330(2):264-71. PubMed ID: 15203332
[TBL] [Abstract][Full Text] [Related]
12. Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention.
Kawaguchi K; Han Q; Li S; Tan Y; Igarashi K; Kiyuna T; Miyake K; Miyake M; Chmielowski B; Nelson SD; Russell TA; Dry SM; Li Y; Singh AS; Eckardt MA; Unno M; Eilber FC; Hoffman RM
Cell Cycle; 2018; 17(3):356-361. PubMed ID: 29187018
[TBL] [Abstract][Full Text] [Related]
13. Effective Metabolic Targeting of Human Osteosarcoma Cells
Igarashi K; Kawaguchi K; Kiyuna T; Miyake K; Murakami T; Yamamoto N; Hayashi K; Kimura H; Miwa S; Tsuchiya H; Hoffman RM
Anticancer Res; 2017 Sep; 37(9):4807-4812. PubMed ID: 28870899
[TBL] [Abstract][Full Text] [Related]
14. Development of recombinant methioninase to target the general cancer-specific metabolic defect of methionine dependence: a 40-year odyssey.
Hoffman RM
Expert Opin Biol Ther; 2015 Jan; 15(1):21-31. PubMed ID: 25439528
[TBL] [Abstract][Full Text] [Related]
15. Afterword: Oral Methioninase-Answer to Cancer and Fountain of Youth?
Hoffman RM; Han Q; Kawaguchi K; Li S; Tan Y
Methods Mol Biol; 2019; 1866():311-322. PubMed ID: 30725426
[TBL] [Abstract][Full Text] [Related]
16. Pilot Phase I Clinical Trial of Methioninase on High-Stage Cancer Patients: Rapid Depletion of Circulating Methionine.
Hoffman RM; Tan Y; Li S; Han Q; Zavala J; Zavala J
Methods Mol Biol; 2019; 1866():231-242. PubMed ID: 30725419
[TBL] [Abstract][Full Text] [Related]
17. Recombinant methioninase infusion reduces the biochemical endpoint of serum methionine with minimal toxicity in high-stage cancer patients.
Tan Y; Zavala J; Han Q; Xu M; Sun X; Tan X; Tan X; Magana R; Geller J; Hoffman RM
Anticancer Res; 1997; 17(5B):3857-60. PubMed ID: 9427792
[TBL] [Abstract][Full Text] [Related]
18. Methioninase gene therapy of human cancer cells is synergistic with recombinant methioninase treatment.
Miki K; Al-Refaie W; Xu M; Jiang P; Tan Y; Bouvet M; Zhao M; Gupta A; Chishima T; Shimada H; Makuuchi M; Moossa AR; Hoffman RM
Cancer Res; 2000 May; 60(10):2696-702. PubMed ID: 10825143
[TBL] [Abstract][Full Text] [Related]
19. Physicochemical and pharmacokinetic characterization of highly potent recombinant L-methionine gamma-lyase conjugated with polyethylene glycol as an antitumor agent.
Takakura T; Takimoto A; Notsu Y; Yoshida H; Ito T; Nagatome H; Ohno M; Kobayashi Y; Yoshioka T; Inagaki K; Yagi S; Hoffman RM; Esaki N
Cancer Res; 2006 Mar; 66(5):2807-14. PubMed ID: 16510603
[TBL] [Abstract][Full Text] [Related]
20. Broad selective efficacy of rMETase and PEG-rMETase on cancer cells in vitro.
Tan Y; Xu M; Hoffman RM
Anticancer Res; 2010 Mar; 30(3):793-8. PubMed ID: 20392998
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]