These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 30726709)

  • 1. Clinical applications of small molecule inhibitors of Pregnane X receptor.
    Staudinger JL
    Mol Cell Endocrinol; 2019 Apr; 485():61-71. PubMed ID: 30726709
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles.
    Burk O; Kuzikov M; Kronenberger T; Jeske J; Keminer O; Thasler WE; Schwab M; Wrenger C; Windshügel B
    Arch Toxicol; 2018 Apr; 92(4):1435-1451. PubMed ID: 29356861
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Strategies for developing pregnane X receptor antagonists: Implications from metabolism to cancer.
    Chai SC; Wright WC; Chen T
    Med Res Rev; 2020 May; 40(3):1061-1083. PubMed ID: 31782213
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression.
    Hartley DP; Dai X; He YD; Carlini EJ; Wang B; Huskey SE; Ulrich RG; Rushmore TH; Evers R; Evans DC
    Mol Pharmacol; 2004 May; 65(5):1159-71. PubMed ID: 15102944
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cannabidiol promotes intestinal cholesterol uptake mediated by Pregnane X receptor.
    Brown C; Kariuki W; Zhong HA; Kippes A; Sui Y
    Front Endocrinol (Lausanne); 2024; 15():1398462. PubMed ID: 38957441
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pregnane X receptor (PXR) at the crossroads of human metabolism and disease.
    Koutsounas I; Theocharis S; Patsouris E; Giaginis C
    Curr Drug Metab; 2013 Mar; 14(3):341-50. PubMed ID: 23237007
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation Modulates the Coregulatory Protein Exchange of the Nuclear Receptor Pregnane X Receptor.
    Cui W; Shen X; Agbas E; Tompkins B; Cameron-Carter H; Staudinger JL
    J Pharmacol Exp Ther; 2020 Jun; 373(3):370-380. PubMed ID: 32205367
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Role of pregnane X receptor (PXR) in endobiotic metabolism].
    Luan ZL; Huo XX; Guan YF; Zhang XY
    Sheng Li Xue Bao; 2019 Apr; 71(2):311-318. PubMed ID: 31008491
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Associations between Pregnane X Receptor and Breast Cancer Growth and Progression.
    Creamer BA; Sloan SNB; Dennis JF; Rogers R; Spencer S; McCuen A; Persaud P; Staudinger JL
    Cells; 2020 Oct; 9(10):. PubMed ID: 33076284
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of pregnane X receptor in chemotherapeutic treatment.
    Zhuo W; Hu L; Lv J; Wang H; Zhou H; Fan L
    Cancer Chemother Pharmacol; 2014 Aug; 74(2):217-27. PubMed ID: 24889719
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pregnane X Receptor Activation Attenuates Inflammation-Associated Intestinal Epithelial Barrier Dysfunction by Inhibiting Cytokine-Induced Myosin Light-Chain Kinase Expression and c-Jun N-Terminal Kinase 1/2 Activation.
    Garg A; Zhao A; Erickson SL; Mukherjee S; Lau AJ; Alston L; Chang TK; Mani S; Hirota SA
    J Pharmacol Exp Ther; 2016 Oct; 359(1):91-101. PubMed ID: 27440420
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pregnane X receptor and natural products: beyond drug-drug interactions.
    Staudinger JL; Ding X; Lichti K
    Expert Opin Drug Metab Toxicol; 2006 Dec; 2(6):847-57. PubMed ID: 17125405
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pregnane X receptor and human malignancy.
    Koutsounas I; Patsouris E; Theocharis S
    Histol Histopathol; 2013 Apr; 28(4):405-20. PubMed ID: 23413096
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 3,4-methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition.
    Antolino-Lobo I; Meulenbelt J; Nijmeijer SM; Maas-Bakker RF; Meijerman I; van den Berg M; van Duursen MB
    Toxicol Lett; 2011 May; 203(1):82-91. PubMed ID: 21402137
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PXR-mediated idiosyncratic drug-induced liver injury: mechanistic insights and targeting approaches.
    Wang J; Bwayi M; Gee RRF; Chen T
    Expert Opin Drug Metab Toxicol; 2020 Aug; 16(8):711-722. PubMed ID: 32500752
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel functions of PXR in cardiometabolic disease.
    Zhou C
    Biochim Biophys Acta; 2016 Sep; 1859(9):1112-1120. PubMed ID: 26924429
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of nuclear receptor PXR impairs glucose tolerance and dysregulates GLUT2 expression and subcellular localization in liver.
    Hassani-Nezhad-Gashti F; Rysä J; Kummu O; Näpänkangas J; Buler M; Karpale M; Hukkanen J; Hakkola J
    Biochem Pharmacol; 2018 Feb; 148():253-264. PubMed ID: 29309761
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Interface between Cell Signaling Pathways and Pregnane X Receptor.
    Rogers RS; Parker A; Vainer PD; Elliott E; Sudbeck D; Parimi K; Peddada VP; Howe PG; D'Ambrosio N; Ruddy G; Stackable K; Carney M; Martin L; Osterholt T; Staudinger JL
    Cells; 2021 Nov; 10(11):. PubMed ID: 34831484
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Essential oils of culinary herbs and spices activate PXR and induce CYP3A4 in human intestinal and hepatic in vitro models.
    Bartonkova I; Dvorak Z
    Toxicol Lett; 2018 Oct; 296():1-9. PubMed ID: 30071242
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice.
    Barretto SA; Lasserre F; Huillet M; Régnier M; Polizzi A; Lippi Y; Fougerat A; Person E; Bruel S; Bétoulières C; Naylies C; Lukowicz C; Smati S; Guzylack L; Olier M; Théodorou V; Mselli-Lakhal L; Zalko D; Wahli W; Loiseau N; Gamet-Payrastre L; Guillou H; Ellero-Simatos S
    Microbiome; 2021 Apr; 9(1):93. PubMed ID: 33879258
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.