BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 30738663)

  • 1. Synthesis of 2-,4,-6-, and/or 7-substituted quinoline derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents: 3D QSAR-assisted design.
    Vyas VK; Qureshi G; Oza D; Patel H; Parmar K; Patel P; Ghate MD
    Bioorg Med Chem Lett; 2019 Apr; 29(7):917-922. PubMed ID: 30738663
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and pharmacological evaluation of novel substituted quinoline-2-carboxamide derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents.
    Vyas VK; Variya B; Ghate MD
    Eur J Med Chem; 2014 Jul; 82():385-93. PubMed ID: 24929289
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of docking-based 3D QSAR models for the design of substituted quinoline derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors.
    Vyas VK; Ghate M
    SAR QSAR Environ Res; 2013 Aug; 24(8):625-45. PubMed ID: 23714018
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: Synthesis, cytotoxicity, lipophilicity and molecular docking studies.
    Petrović MM; Roschger C; Chaudary S; Zierer A; Mladenović M; Jakovljević K; Marković V; Botta B; Joksović MD
    Bioorg Chem; 2020 Dec; 105():104373. PubMed ID: 33074120
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural Optimization and Structure-Activity Relationship of 4-Thiazolidinone Derivatives as Novel Inhibitors of Human Dihydroorotate Dehydrogenase.
    Zeng F; Quan L; Yang G; Qi T; Zhang L; Li S; Li H; Zhu L; Xu X
    Molecules; 2019 Jul; 24(15):. PubMed ID: 31370178
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Low cytotoxic quinoline-4-carboxylic acids derived from vanillin precursors as potential human dihydroorotate dehydrogenase inhibitors.
    Petrović MM; Roschger C; Chaudary S; Zierer A; Mladenović M; Marković V; Trifunović S; Joksović MD
    Bioorg Med Chem Lett; 2021 Aug; 46():128194. PubMed ID: 34116160
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Patent Review of Human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors as Anticancer Agents and their Other Therapeutic Applications (1999-2022).
    Gehlot P; Vyas VK
    Recent Pat Anticancer Drug Discov; 2024; 19(3):280-297. PubMed ID: 37070439
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and biological evaluation of novel substituted benzamide derivatives bearing a 1,2,3-triazole moiety as potent human dihydroorotate dehydrogenase inhibitors.
    Lu K; Cai L; Zhang X; Wu G; Xu C; Zhao Y; Gong P
    Bioorg Chem; 2018 Feb; 76():528-537. PubMed ID: 29316525
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and inhibitory activity against human dihydroorotate dehydrogenase (hDHODH) of 1,3-benzoazole derivatives bearing amide units.
    Li J; Wu D; Xu X; Huang J; Shao X; Li Z
    Bioorg Med Chem Lett; 2016 Jul; 26(13):3064-3066. PubMed ID: 27220723
    [TBL] [Abstract][Full Text] [Related]  

  • 10. QSAR study on a series of aryl carboxylic acid amide derivatives as potential inhibitors of dihydroorotate dehydrogenase (DHODH).
    Vyas VK; Ghate M
    Med Chem; 2013 Mar; 9(2):222-39. PubMed ID: 22920152
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Liquid phase combinatorial synthesis of 1,2,5-trisubstituted benzimidazole derivatives as human DHODH inhibitors.
    Sitwala ND; Vyas VK; Variya BC; Patel SS; Mehta CC; Rana DN; Ghate MD
    Bioorg Chem; 2017 Dec; 75():118-126. PubMed ID: 28941392
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of new quinoline-4-carboxylic acid-chalcone hybrids as dihydroorotate dehydrogenase inhibitors.
    Petrović MM; Roschger C; Lang K; Zierer A; Mladenović M; Trifunović S; Mandić B; Joksović MD
    Arch Pharm (Weinheim); 2023 Feb; 356(2):e2200374. PubMed ID: 36372522
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rational Design of Benzylidenehydrazinyl-Substituted Thiazole Derivatives as Potent Inhibitors of Human Dihydroorotate Dehydrogenase with in Vivo Anti-arthritic Activity.
    Li S; Luan G; Ren X; Song W; Xu L; Xu M; Zhu J; Dong D; Diao Y; Liu X; Zhu L; Wang R; Zhao Z; Xu Y; Li H
    Sci Rep; 2015 Oct; 5():14836. PubMed ID: 26443076
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bifunctional Naphtho[2,3-
    Zuo Z; Liu X; Qian X; Zeng T; Sang N; Liu H; Zhou Y; Tao L; Zhou X; Su N; Yu Y; Chen Q; Luo Y; Zhao Y
    J Med Chem; 2020 Jul; 63(14):7633-7652. PubMed ID: 32496056
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds.
    Sainas S; Pippione AC; Giorgis M; Lupino E; Goyal P; Ramondetti C; Buccinnà B; Piccinini M; Braga RC; Andrade CH; Andersson M; Moritzer AC; Friemann R; Mensa S; Al-Kadaraghi S; Boschi D; Lolli ML
    Eur J Med Chem; 2017 Mar; 129():287-302. PubMed ID: 28235702
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of a human dihydroorotate dehydrogenase (hDHODH) pharma-similarity index approach with scaffold-hopping strategy for the design of novel potential inhibitors.
    Shih KC; Lee CC; Tsai CN; Lin YS; Tang CY
    PLoS One; 2014; 9(2):e87960. PubMed ID: 24504131
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors.
    Sainas S; Pippione AC; Lupino E; Giorgis M; Circosta P; Gaidano V; Goyal P; Bonanni D; Rolando B; Cignetti A; Ducime A; Andersson M; Järvå M; Friemann R; Piccinini M; Ramondetti C; Buccinnà B; Al-Karadaghi S; Boschi D; Saglio G; Lolli ML
    J Med Chem; 2018 Jul; 61(14):6034-6055. PubMed ID: 29939742
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of a novel series of hDHODH inhibitors with anti-pulmonary fibrotic activities.
    Lu K; Zhao Y; Wu G; Hu H; Wang M; Gong G; Jiang Y
    Bioorg Chem; 2019 May; 86():44-51. PubMed ID: 30685643
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-phenyl ureidobenzenesulfonates, a novel class of promising human dihydroorotate dehydrogenase inhibitors.
    Bouzriba C; Larcher L; Gagné-Boulet M; Fortin S
    Bioorg Med Chem; 2020 Nov; 28(22):115739. PubMed ID: 33007554
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, Design, and Structure⁻Activity Relationship of the Pyrimidone Derivatives as Novel Selective Inhibitors of
    Xu L; Li W; Diao Y; Sun H; Li H; Zhu L; Zhou H; Zhao Z
    Molecules; 2018 May; 23(6):. PubMed ID: 29794978
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.