These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 30740744)

  • 1. Imaging metabotropic glutamate receptor system: Application of positron emission tomography technology in drug development.
    Xu Y; Li Z
    Med Res Rev; 2019 Sep; 39(5):1892-1922. PubMed ID: 30740744
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Relationship between in vivo receptor occupancy and efficacy of metabotropic glutamate receptor subtype 5 allosteric modulators with different in vitro binding profiles.
    Rook JM; Tantawy MN; Ansari MS; Felts AS; Stauffer SR; Emmitte KA; Kessler RM; Niswender CM; Daniels JS; Jones CK; Lindsley CW; Conn PJ
    Neuropsychopharmacology; 2015 Feb; 40(3):755-65. PubMed ID: 25241804
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vivo imaging of the metabotropic glutamate receptor 1 (mGluR1) with positron emission tomography: recent advance and perspective.
    Li S; Huang Y
    Curr Med Chem; 2014; 21(1):113-23. PubMed ID: 23992339
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro binding of a radio-labeled positive allosteric modulator for metabotropic glutamate receptor subtype 5.
    Zysk JR; Spear N; Fieles W; Stein MM; Sygowski LS; King MM; Hoesch V; Hastings R; Brockel B; Do M; Ström P; Gadient R; Chhajlani V; Elmore CS; Maier DL
    Synapse; 2013 Mar; 67(3):135-44. PubMed ID: 23150216
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Negative allosteric modulation of metabotropic glutamate receptor 5 results in broad spectrum activity relevant to treatment resistant depression.
    Hughes ZA; Neal SJ; Smith DL; Sukoff Rizzo SJ; Pulicicchio CM; Lotarski S; Lu S; Dwyer JM; Brennan J; Olsen M; Bender CN; Kouranova E; Andree TH; Harrison JE; Whiteside GT; Springer D; O'Neil SV; Leonard SK; Schechter LE; Dunlop J; Rosenzweig-Lipson S; Ring RH
    Neuropharmacology; 2013 Mar; 66():202-14. PubMed ID: 22551786
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Translational neurophysiological markers for activity of the metabotropic glutamate receptor (mGluR2) modulator JNJ-40411813: Sleep EEG correlates in rodents and healthy men.
    Ahnaou A; de Boer P; Lavreysen H; Huysmans H; Sinha V; Raeymaekers L; Van De Casteele T; Cid JM; Van Nueten L; Macdonald GJ; Kemp JA; Drinkenburg WH
    Neuropharmacology; 2016 Apr; 103():290-305. PubMed ID: 26686390
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Screening cascade and development of potential Positron Emission Tomography radiotracers for mGluR5: in vitro and in vivo characterization.
    Patel S; Ndubizu O; Hamill T; Chaudhary A; Burns HD; Hargreaves R; Gibson RE
    Mol Imaging Biol; 2005; 7(4):314-23. PubMed ID: 16080024
    [TBL] [Abstract][Full Text] [Related]  

  • 8. What We Observe In Vivo Is Not Always What We See In Vitro: Development and Validation of 11C-JNJ-42491293, A Novel Radioligand for mGluR2.
    Leurquin-Sterk G; Celen S; Van Laere K; Koole M; Bormans G; Langlois X; Van Hecken A; Te Riele P; Alcázar J; Verbruggen A; de Hoon J; Andrés JI; Schmidt ME
    J Nucl Med; 2017 Jan; 58(1):110-116. PubMed ID: 27469358
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Advances and Insights in Positron Emission Tomography Tracers for Metabotropic Glutamate Receptor 4 Imaging.
    Wang J; Li Y; El Fakhri G
    J Med Chem; 2024 Jul; 67(13):10517-10529. PubMed ID: 38924702
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, evaluation, and radiolabeling of new potent positive allosteric modulators of the metabotropic glutamate receptor 2 as potential tracers for positron emission tomography imaging.
    Andrés JI; Alcázar J; Cid JM; De Angelis M; Iturrino L; Langlois X; Lavreysen H; Trabanco AA; Celen S; Bormans G
    J Med Chem; 2012 Oct; 55(20):8685-99. PubMed ID: 22992024
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Translational Model-Informed Dose Selection for a Human Positron Emission Tomography Imaging Study of JNJ-54175446, a P2X7 Receptor Antagonist.
    Xu Y; Miao X; Ravenstijn P; Hijzen A; Schmidt ME; Nandy P; Zhou H
    Clin Transl Sci; 2020 Mar; 13(2):309-317. PubMed ID: 31642608
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of [
    Takano A; Nag S; Jia Z; Jahan M; Forsberg A; Arakawa R; Grybäck P; Duvey G; Halldin C; Charvin D
    Mol Imaging Biol; 2019 Jun; 21(3):500-508. PubMed ID: 30066121
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, characterization, and monkey PET studies of [¹⁸F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435.
    Hostetler ED; Eng W; Joshi AD; Sanabria-Bohórquez S; Kawamoto H; Ito S; O'Malley S; Krause S; Ryan C; Patel S; Williams M; Riffel K; Suzuki G; Ozaki S; Ohta H; Cook J; Burns HD; Hargreaves R
    Synapse; 2011 Feb; 65(2):125-35. PubMed ID: 20524178
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabotropic glutamate receptors as therapeutic targets in Parkinson's disease: An update from the last 5 years of research.
    Litim N; Morissette M; Di Paolo T
    Neuropharmacology; 2017 Mar; 115():166-179. PubMed ID: 27055772
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of 4-(2-fluoro-4-[
    Kumata K; Hatori A; Yamasaki T; Zhang Y; Mori W; Fujinaga M; Xie L; Nengaki N; Zhang MR
    Bioorg Med Chem; 2019 Feb; 27(3):483-491. PubMed ID: 30611634
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of [(18)F]-PSS223 as a PET tracer for imaging of metabotropic glutamate receptor subtype 5 (mGluR5).
    Sephton SM; Dennler P; Leutwiler DS; Mu L; Schibli R; Krämer SD; Ametamey SM
    Chimia (Aarau); 2012; 66(4):201-4. PubMed ID: 22613149
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The application of positron emission tomography (PET) imaging in CNS drug development.
    Suridjan I; Comley RA; Rabiner EA
    Brain Imaging Behav; 2019 Apr; 13(2):354-365. PubMed ID: 30259405
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impact of allosteric modulation: Exploring the binding kinetics of glutamate and other orthosteric ligands of the metabotropic glutamate receptor 2.
    Doornbos MLJ; Vermond SC; Lavreysen H; Tresadern G; IJzerman AP; Heitman LH
    Biochem Pharmacol; 2018 Sep; 155():356-365. PubMed ID: 30028996
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Preclinical anaylses of [
    Lee B; Kim YK; Lee JY; Kim YJ; Lee YS; Lee DS; Chung JK; Jeong JM
    J Cereb Blood Flow Metab; 2017 Jun; 37(6):2283-2293. PubMed ID: 27501957
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Radiolabeling and in vitro and in vivo evaluation of [18F]-FE-DABP688 as a PET radioligand for the metabotropic glutamate receptor subtype 5.
    Honer M; Stoffel A; Kessler LJ; Schubiger PA; Ametamey SM
    Nucl Med Biol; 2007 Nov; 34(8):973-80. PubMed ID: 17998101
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.