339 related articles for article (PubMed ID: 30747554)
21. A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry.
Dierks EA; Stams KR; Lim HK; Cornelius G; Zhang H; Ball SE
Drug Metab Dispos; 2001 Jan; 29(1):23-9. PubMed ID: 11124225
[TBL] [Abstract][Full Text] [Related]
22. Development and validation of an in vitro, seven-in-one human cytochrome P450 assay for evaluation of both direct and time-dependent inhibition.
Dahlinger D; Duechting S; Nuecken D; Sydow K; Fuhr U; Frechen S
J Pharmacol Toxicol Methods; 2016; 77():66-75. PubMed ID: 26528794
[TBL] [Abstract][Full Text] [Related]
23. Development of an in vitro drug-drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds.
Zientek M; Miller H; Smith D; Dunklee MB; Heinle L; Thurston A; Lee C; Hyland R; Fahmi O; Burdette D
J Pharmacol Toxicol Methods; 2008; 58(3):206-14. PubMed ID: 18634893
[TBL] [Abstract][Full Text] [Related]
24. High-throughput screening of inhibitory potential of nine cytochrome P450 enzymes in vitro using liquid chromatography/tandem mass spectrometry.
Kim MJ; Kim H; Cha IJ; Park JS; Shon JH; Liu KH; Shin JG
Rapid Commun Mass Spectrom; 2005; 19(18):2651-8. PubMed ID: 16124035
[TBL] [Abstract][Full Text] [Related]
25. Evaluation of the effect of Bovis Calculus Artifactus on eight rat liver cytochrome P450 isozymes using LC-MS/MS and cocktail approach.
Zhang YJ; Zhou WL; Yu F; Wang Q; Peng C; Kan JY
Xenobiotica; 2021 Sep; 51(9):1010-1018. PubMed ID: 34294011
[TBL] [Abstract][Full Text] [Related]
26. Direct inhibition of Re Du Ning Injection and its active compounds on human liver cytochrome P450 enzymes by a cocktail method.
Kang D; Geng T; Lian Y; Li Y; Ding G; Huang W; Ma S; Wang Z; Ma Z; Xiao W
Biomed Chromatogr; 2017 Jul; 31(7):. PubMed ID: 27891633
[TBL] [Abstract][Full Text] [Related]
27. Development of a method to determine cytochrome P450 1A2, 2C9, 2D6 and 3A4 activity sheep hepatic microsomes.
McBride GM; Soo JY; Varcoe T; Morrison JL; Wiese MD
J Pharmacol Toxicol Methods; 2020; 106():106934. PubMed ID: 33080390
[TBL] [Abstract][Full Text] [Related]
28. In vitro assessment of cytochrome P450 inhibition: strategies for increasing LC/MS-based assay throughput using a one-point IC(50) method and multiplexing high-performance liquid chromatography.
Lin T; Pan K; Mordenti J; Pan L
J Pharm Sci; 2007 Sep; 96(9):2485-93. PubMed ID: 17542019
[TBL] [Abstract][Full Text] [Related]
29. AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5'-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
Kim JH; Kwon SS; Kong TY; Cheong JC; Kim HS; In MK; Lee HS
Molecules; 2017 Mar; 22(3):. PubMed ID: 28287454
[TBL] [Abstract][Full Text] [Related]
30. Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine.
Wójcikowski J; Pichard-Garcia L; Maurel P; Daniel WA
Br J Pharmacol; 2003 Apr; 138(8):1465-74. PubMed ID: 12721102
[TBL] [Abstract][Full Text] [Related]
31. Development and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes).
Palacharla VRC; Chunduru P; Ajjala DR; Bhyrapuneni G; Nirogi R; Li AP
Drug Metab Dispos; 2019 Oct; 47(10):1032-1039. PubMed ID: 31375472
[TBL] [Abstract][Full Text] [Related]
32. In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with monoclonal anti-CYP antibodies.
Tolonen A; Petsalo A; Turpeinen M; Uusitalo J; Pelkonen O
J Mass Spectrom; 2007 Jul; 42(7):960-6. PubMed ID: 17565714
[TBL] [Abstract][Full Text] [Related]
33. Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design.
Perloff ES; Mason AK; Dehal SS; Blanchard AP; Morgan L; Ho T; Dandeneau A; Crocker RM; Chandler CM; Boily N; Crespi CL; Stresser DM
Xenobiotica; 2009 Feb; 39(2):99-112. PubMed ID: 19255936
[TBL] [Abstract][Full Text] [Related]
34. [Simultaneous determination of the inhibitory potency of compounds on the activity of five cytochrome P-450 enzymes using a cocktail probe substrates method].
Gao ZW; Shi XJ; Yu C; Li SJ; Zhong MK
Yao Xue Xue Bao; 2007 Jun; 42(6):589-94. PubMed ID: 17702393
[TBL] [Abstract][Full Text] [Related]
35. In vitro evaluation of the inhibition potential of echinacoside on human cytochrome P450 isozymes.
Wu Y; Qiao A; Lin S; Chen L
BMC Complement Med Ther; 2022 Feb; 22(1):46. PubMed ID: 35180866
[TBL] [Abstract][Full Text] [Related]
36. Development and full validation of six inhibition assays for five major cytochrome P450 enzymes in human liver microsomes using an automated 96-well microplate incubation format and LC-MS/MS analysis.
Yao M; Zhu M; Sinz MW; Zhang H; Humphreys WG; Rodrigues AD; Dai R
J Pharm Biomed Anal; 2007 May; 44(1):211-23. PubMed ID: 17418993
[TBL] [Abstract][Full Text] [Related]
37. Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes.
Wen X; Wang JS; Neuvonen PJ; Backman JT
Eur J Clin Pharmacol; 2002 Jan; 57(11):799-804. PubMed ID: 11868802
[TBL] [Abstract][Full Text] [Related]
38. Inhibitory mechanisms of celastrol on human liver cytochrome P450 1A2, 2C19, 2D6, 2E1 and 3A4.
Jin C; He X; Zhang F; He L; Chen J; Wang L; An L; Fan Y
Xenobiotica; 2015; 45(7):571-7. PubMed ID: 25811791
[TBL] [Abstract][Full Text] [Related]
39. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate.
Yu C; Shin YG; Kosmeder JW; Pezzuto JM; van Breemen RB
Rapid Commun Mass Spectrom; 2003; 17(4):307-13. PubMed ID: 12569440
[TBL] [Abstract][Full Text] [Related]
40. Cocktail-substrate approach-based high-throughput assay for evaluation of direct and time-dependent inhibition of multiple cytochrome P450 isoforms.
Kozakai K; Yamada Y; Oshikata M; Kawase T; Suzuki E; Haramaki Y; Taniguchi H
Drug Metab Pharmacokinet; 2014; 29(2):198-207. PubMed ID: 24172718
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
