These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 30755818)

  • 1. Synergistic effects of SHP2 and PI3K pathway inhibitors in GAB2-overexpressing ovarian cancer.
    Sun B; Jensen NR; Chung D; Yang M; LaRue AC; Cheung HW; Wang Q
    Am J Cancer Res; 2019; 9(1):145-159. PubMed ID: 30755818
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating chemokine expression.
    Duckworth C; Zhang L; Carroll SL; Ethier SP; Cheung HW
    Oncogene; 2016 Aug; 35(31):4036-47. PubMed ID: 26657155
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene.
    Dunn GP; Cheung HW; Agarwalla PK; Thomas S; Zektser Y; Karst AM; Boehm JS; Weir BA; Berlin AM; Zou L; Getz G; Liu JF; Hirsch M; Vazquez F; Root DE; Beroukhim R; Drapkin R; Hahn WC
    Proc Natl Acad Sci U S A; 2014 Jan; 111(3):1102-7. PubMed ID: 24385586
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition.
    Davis SJ; Sheppard KE; Anglesio MS; George J; Traficante N; Fereday S; Intermaggio MP; Menon U; Gentry-Maharaj A; Lubinski J; Gronwald J; Pearce CL; Pike MC; Wu A; Kommoss S; Pfisterer J; du Bois A; Hilpert F; Ramus SJ; Bowtell DD; Huntsman DG; Pearson RB; Simpson KJ; Campbell IG; Gorringe KL
    Mol Cancer Ther; 2015 Jun; 14(6):1495-503. PubMed ID: 25852062
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1.
    Gu S; Chan WW; Mohi G; Rosenbaum J; Sayad A; Lu Z; Virtanen C; Li S; Neel BG; Van Etten RA
    Blood; 2016 Apr; 127(14):1803-13. PubMed ID: 26773044
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Elevated expressions of SHP2 and GAB2 correlated with VEGF in eutopic and ectopic endometrium of women with ovarian endometriosis.
    Huang Y; Zhang T; Chen L; Yu M; Liu Q; Zhou C; Tang Q; Zhou L; Zhan H; Li J; Xu K; Lin J
    Gynecol Endocrinol; 2020 Sep; 36(9):813-818. PubMed ID: 32619126
    [No Abstract]   [Full Text] [Related]  

  • 7. Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter.
    Nyga R; Pecquet C; Harir N; Gu H; Dhennin-Duthille I; Régnier A; Gouilleux-Gruart V; Lassoued K; Gouilleux F
    Biochem J; 2005 Aug; 390(Pt 1):359-66. PubMed ID: 15833084
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gab2 promotes cancer stem cell like properties and metastatic growth of ovarian cancer via downregulation of miR-200c.
    Fang Z; Li T; Chen W; Wu D; Qin Y; Liu M; Wu G; He L; Li H; Gu H
    Exp Cell Res; 2019 Sep; 382(1):111462. PubMed ID: 31194976
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Critical Role for GAB2 in Neuroblastoma Pathogenesis through the Promotion of SHP2/MYCN Cooperation.
    Zhang X; Dong Z; Zhang C; Ung CY; He S; Tao T; Oliveira AM; Meves A; Ji B; Look AT; Li H; Neel BG; Zhu S
    Cell Rep; 2017 Mar; 18(12):2932-2942. PubMed ID: 28329685
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes.
    Miyakawa Y; Rojnuckarin P; Habib T; Kaushansky K
    J Biol Chem; 2001 Jan; 276(4):2494-502. PubMed ID: 11054408
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphoinositide 3-kinase-dependent regulation of interleukin-3-induced proliferation: involvement of mitogen-activated protein kinases, SHP2 and Gab2.
    Craddock BL; Hobbs J; Edmead CE; Welham MJ
    J Biol Chem; 2001 Jun; 276(26):24274-83. PubMed ID: 11335710
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gab2 tyrosine phosphorylation by a pleckstrin homology domain-independent mechanism: role in epidermal growth factor-induced mitogenesis.
    Kong M; Mounier C; Balbis A; Baquiran G; Posner BI
    Mol Endocrinol; 2003 May; 17(5):935-44. PubMed ID: 12595575
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gab2 Ablation Reverses the Stemness of HER2-Overexpressing Breast Cancer Cells.
    Zhang P; Chen Y; Gong M; Zhuang Z; Wang Y; Mu L; Wang T; Pan J; Liu Y; Xu J; Liang R; Yuan Y
    Cell Physiol Biochem; 2018; 50(1):52-65. PubMed ID: 30326469
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.
    Chen YN; LaMarche MJ; Chan HM; Fekkes P; Garcia-Fortanet J; Acker MG; Antonakos B; Chen CH; Chen Z; Cooke VG; Dobson JR; Deng Z; Fei F; Firestone B; Fodor M; Fridrich C; Gao H; Grunenfelder D; Hao HX; Jacob J; Ho S; Hsiao K; Kang ZB; Karki R; Kato M; Larrow J; La Bonte LR; Lenoir F; Liu G; Liu S; Majumdar D; Meyer MJ; Palermo M; Perez L; Pu M; Price E; Quinn C; Shakya S; Shultz MD; Slisz J; Venkatesan K; Wang P; Warmuth M; Williams S; Yang G; Yuan J; Zhang JH; Zhu P; Ramsey T; Keen NJ; Sellers WR; Stams T; Fortin PD
    Nature; 2016 Jul; 535(7610):148-52. PubMed ID: 27362227
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of the Erk2-Elk1 signaling pathway and megakaryocytic differentiation of Bcr-Abl(+) K562 leukemic cells by Gab2.
    Dorsey JF; Cunnick JM; Mane SM; Wu J
    Blood; 2002 Feb; 99(4):1388-97. PubMed ID: 11830491
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A role for the scaffolding adapter GAB2 in breast cancer.
    Bentires-Alj M; Gil SG; Chan R; Wang ZC; Wang Y; Imanaka N; Harris LN; Richardson A; Neel BG; Gu H
    Nat Med; 2006 Jan; 12(1):114-21. PubMed ID: 16369543
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosine phosphatase SHP2 inhibitors in tumor-targeted therapies.
    Song Z; Wang M; Ge Y; Chen XP; Xu Z; Sun Y; Xiong XF
    Acta Pharm Sin B; 2021 Jan; 11(1):13-29. PubMed ID: 33532178
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Scaffolding protein Gab2 mediates fibroblast transformation by the SEA tyrosine kinase.
    Ischenko I; Petrenko O; Gu H; Hayman MJ
    Oncogene; 2003 Sep; 22(41):6311-8. PubMed ID: 14508511
    [TBL] [Abstract][Full Text] [Related]  

  • 19. G-CSF-dependent neutrophil differentiation requires downregulation of MAPK activities through the Gab2 signaling pathway.
    Zhao X; Kawano SI; Masuda J; Murakami H
    Cell Biol Int; 2020 Sep; 44(9):1919-1933. PubMed ID: 32437087
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers.
    Hao HX; Wang H; Liu C; Kovats S; Velazquez R; Lu H; Pant B; Shirley M; Meyer MJ; Pu M; Lim J; Fleming M; Alexander L; Farsidjani A; LaMarche MJ; Moody S; Silver SJ; Caponigro G; Stuart DD; Abrams TJ; Hammerman PS; Williams J; Engelman JA; Goldoni S; Mohseni M
    Mol Cancer Ther; 2019 Dec; 18(12):2368-2380. PubMed ID: 31439712
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 9.