These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 30759032)

  • 21. Long-term elevation of free fatty acids leads to delayed processing of proinsulin and prohormone convertases 2 and 3 in the pancreatic beta-cell line MIN6.
    Furukawa H; Carroll RJ; Swift HH; Steiner DF
    Diabetes; 1999 Jul; 48(7):1395-401. PubMed ID: 10389844
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Proinsulin maturation disorder is a contributor to the defect of subsequent conversion to insulin in β-cells.
    Wang J; Osei K
    Biochem Biophys Res Commun; 2011 Jul; 411(1):150-5. PubMed ID: 21723250
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Electron microscopic immunocytochemical evidence for the involvement of the convertases PC1 and PC2 in the processing of proinsulin in pancreatic beta-cells.
    Malide D; Seidah NG; Chrétien M; Bendayan M
    J Histochem Cytochem; 1995 Jan; 43(1):11-9. PubMed ID: 7822759
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets.
    Marcinkiewicz M; Ramla D; Seidah NG; Chrétien M
    Endocrinology; 1994 Oct; 135(4):1651-60. PubMed ID: 7925129
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Altered proinsulin conversion in rat pancreatic islets exposed long-term to various glucose concentrations or interleukin-1beta.
    Börjesson A; Carlsson C
    J Endocrinol; 2007 Feb; 192(2):381-7. PubMed ID: 17283238
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Prohormone convertases (PC1/3 and PC2) in rat and human pancreas and islet cell tumors: subcellular immunohistochemical analysis.
    Itoh Y; Tanaka S; Takekoshi S; Itoh J; Osamura RY
    Pathol Int; 1996 Oct; 46(10):726-37. PubMed ID: 8916141
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Functioning human insulinomas. An immunohistochemical analysis of intracellular insulin processing.
    Azzoni C; D'Adda T; Tamburrano G; Coscelli C; Madsen OD; Scopsi L; Bordi C
    Virchows Arch; 1998 Dec; 433(6):495-504. PubMed ID: 9870681
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Metformin restores prohormone processing enzymes and normalizes aberrations in secretion of proinsulin and insulin in palmitate-exposed human islets.
    Wen Q; Chowdhury AI; Aydin B; Shekha M; Stenlid R; Forslund A; Bergsten P
    Diabetes Obes Metab; 2023 Dec; 25(12):3757-3765. PubMed ID: 37694762
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Exposure of human islets to cytokines can result in disproportionately elevated proinsulin release.
    Hostens K; Pavlovic D; Zambre Y; Ling Z; Van Schravendijk C; Eizirik DL; Pipeleers DG
    J Clin Invest; 1999 Jul; 104(1):67-72. PubMed ID: 10393700
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The role of prohormone convertases in insulin biosynthesis: evidence for inherited defects in their action in man and experimental animals.
    Steiner DF; Rouillé Y; Gong Q; Martin S; Carroll R; Chan SJ
    Diabetes Metab; 1996 Apr; 22(2):94-104. PubMed ID: 8792089
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Altered islet prohormone processing: a cause or consequence of diabetes?
    Ramzy A; Kieffer TJ
    Physiol Rev; 2022 Jan; 102(1):155-208. PubMed ID: 34280055
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice.
    Chen YC; Taylor AJ; Fulcher JM; Swensen AC; Dai XQ; Komba M; Wrightson KLC; Fok K; Patterson AE; Klein Geltink RI; MacDonald PE; Qian WJ; Verchere CB
    Diabetes; 2023 Sep; 72(9):1277-1288. PubMed ID: 37364047
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Levels of the conversion endoproteases PC1 (PC3) and PC2 distinguish between insulin-producing pancreatic islet beta cells and non-beta cells.
    Neerman-Arbez M; Cirulli V; Halban PA
    Biochem J; 1994 May; 300 ( Pt 1)(Pt 1):57-61. PubMed ID: 8198551
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Defective insulin maturation in patients with type 2 diabetes.
    Huang Y; Zhen J; Liu T; Wang J; Li N; Yang J; Liang R; Wang S; Liu M
    Eur J Endocrinol; 2021 Sep; 185(4):565-576. PubMed ID: 34374650
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line.
    Skelly RH; Schuppin GT; Ishihara H; Oka Y; Rhodes CJ
    Diabetes; 1996 Jan; 45(1):37-43. PubMed ID: 8522057
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Human type 2 diabetes: morphological evidence for abnormal beta-cell function.
    Sempoux C; Guiot Y; Dubois D; Moulin P; Rahier J
    Diabetes; 2001 Feb; 50 Suppl 1():S172-7. PubMed ID: 11272184
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3.
    Smeekens SP; Montag AG; Thomas G; Albiges-Rizo C; Carroll R; Benig M; Phillips LA; Martin S; Ohagi S; Gardner P
    Proc Natl Acad Sci U S A; 1992 Sep; 89(18):8822-6. PubMed ID: 1528899
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The balance between proinsulin biosynthesis and insulin secretion: where can imbalance lead?
    Uchizono Y; Alarcón C; Wicksteed BL; Marsh BJ; Rhodes CJ
    Diabetes Obes Metab; 2007 Nov; 9 Suppl 2():56-66. PubMed ID: 17919179
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Exenatide substantially improves proinsulin conversion and cell survival that augment Ins2
    Tang W; Yuan Q; Xu B; Osei K; Wang J
    Mol Cell Endocrinol; 2017 Jan; 439():297-307. PubMed ID: 27658750
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Endoplasmic reticulum Ca2+ is important for the proteolytic processing and intracellular transport of proinsulin in the pancreatic beta-cell.
    Guest PC; Bailyes EM; Hutton JC
    Biochem J; 1997 Apr; 323 ( Pt 2)(Pt 2):445-50. PubMed ID: 9163336
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.