BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 30760754)

  • 1. Induction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma.
    Kant R; Yen CH; Hung JH; Lu CK; Tung CY; Chang PC; Chen YH; Tyan YC; Chen YA
    Sci Rep; 2019 Feb; 9(1):1968. PubMed ID: 30760754
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma.
    Kant R; Yen CH; Lu CK; Lin YC; Li JH; Chen YM
    Int J Mol Sci; 2016 May; 17(5):. PubMed ID: 27153064
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of an Orally Efficacious MYC Inhibitor for Liver Cancer Using a GNMT-Based High-Throughput Screening System and Structure-Activity Relationship Analysis.
    Kant R; Yang MH; Tseng CH; Yen CH; Li WY; Tyan YC; Chen M; Tzeng CC; Chen WC; You K; Wang WC; Chen YL; Chen YA
    J Med Chem; 2021 Jul; 64(13):8992-9009. PubMed ID: 34132534
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of the GNMT-HectH9-PREX2 tripartite relationship in the pathogenesis of hepatocellular carcinoma.
    Li CH; Yen CH; Chen YF; Lee KJ; Fang CC; Zhang X; Lai CC; Huang SF; Lin HK; Arthur Chen YM
    Int J Cancer; 2017 May; 140(10):2284-2297. PubMed ID: 28205209
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Downregulation of Methionine Cycle Genes
    Chen PM; Tsai CH; Huang CC; Hwang HH; Li JR; Liu CC; Ko HA; Chiang EI
    Int J Mol Sci; 2022 Jan; 23(1):. PubMed ID: 35008908
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma.
    Yen CH; Lu YC; Li CH; Lee CM; Chen CY; Cheng MY; Huang SF; Chen KF; Cheng AL; Liao LY; Lee YH; Chen YM
    Mol Med; 2012 Mar; 18(1):286-96. PubMed ID: 22160218
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IGF2 Is Up-regulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and Is an Actionable Oncogene Product in Experimental Models.
    Martinez-Quetglas I; Pinyol R; Dauch D; Torrecilla S; Tovar V; Moeini A; Alsinet C; Portela A; Rodriguez-Carunchio L; Solé M; Lujambio A; Villanueva A; Thung S; Esteller M; Zender L; Llovet JM
    Gastroenterology; 2016 Dec; 151(6):1192-1205. PubMed ID: 27614046
    [TBL] [Abstract][Full Text] [Related]  

  • 8. AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage.
    Fang CC; Wu CF; Liao YJ; Huang SF; Chen M; Chen YA
    Sci Rep; 2018 Sep; 8(1):13802. PubMed ID: 30217986
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.
    Martínez-López N; García-Rodríguez JL; Varela-Rey M; Gutiérrez V; Fernández-Ramos D; Beraza N; Aransay AM; Schlangen K; Lozano JJ; Aspichueta P; Luka Z; Wagner C; Evert M; Calvisi DF; Lu SC; Mato JM; Martínez-Chantar ML
    Gastroenterology; 2012 Sep; 143(3):787-798.e13. PubMed ID: 22687285
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BCAT1, a key prognostic predictor of hepatocellular carcinoma, promotes cell proliferation and induces chemoresistance to cisplatin.
    Zheng YH; Hu WJ; Chen BC; Grahn TH; Zhao YR; Bao HL; Zhu YF; Zhang QY
    Liver Int; 2016 Dec; 36(12):1836-1847. PubMed ID: 27246112
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of MEK suppresses hepatocellular carcinoma growth through independent MYC and BIM regulation.
    Zhou X; Zhu A; Gu X; Xie G
    Cell Oncol (Dordr); 2019 Jun; 42(3):369-380. PubMed ID: 30788663
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gene Expression and DNA Methylation Alterations in the Glycine N-Methyltransferase Gene in Diet-Induced Nonalcoholic Fatty Liver Disease-Associated Carcinogenesis.
    Borowa-Mazgaj B; de Conti A; Tryndyak V; Steward CR; Jimenez L; Melnyk S; Seneshaw M; Mirshahi F; Rusyn I; Beland FA; Sanyal AJ; Pogribny IP
    Toxicol Sci; 2019 Aug; 170(2):273-282. PubMed ID: 31086990
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SOX1 functions as a tumor suppressor by antagonizing the WNT/β-catenin signaling pathway in hepatocellular carcinoma.
    Tsao CM; Yan MD; Shih YL; Yu PN; Kuo CC; Lin WC; Li HJ; Lin YW
    Hepatology; 2012 Dec; 56(6):2277-87. PubMed ID: 22767186
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice.
    Wang F; Hou W; Chitsike L; Xu Y; Bettler C; Perera A; Bank T; Cotler SJ; Dhanarajan A; Denning MF; Ding X; Breslin P; Qiang W; Li J; Koleske AJ; Qiu W
    Gastroenterology; 2020 Jul; 159(1):289-305.e16. PubMed ID: 32171747
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility.
    Liao YJ; Liu SP; Lee CM; Yen CH; Chuang PC; Chen CY; Tsai TF; Huang SF; Lee YH; Chen YM
    Int J Cancer; 2009 Feb; 124(4):816-26. PubMed ID: 19035462
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reversal of High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Metformin Combined with PGG, an Inducer of Glycine N-Methyltransferase.
    Yang MH; Li WY; Wu CF; Lee YC; Chen AY; Tyan YC; Chen YA
    Int J Mol Sci; 2022 Sep; 23(17):. PubMed ID: 36077467
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mistletoe extract Fraxini inhibits the proliferation of liver cancer by down-regulating c-Myc expression.
    Yang P; Jiang Y; Pan Y; Ding X; Rhea P; Ding J; Hawke DH; Felsher D; Narla G; Lu Z; Lee RT
    Sci Rep; 2019 Apr; 9(1):6428. PubMed ID: 31015523
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1.
    Shi W; Feng L; Dong S; Ning Z; Hua Y; Liu L; Chen Z; Meng Z
    Cell Commun Signal; 2020 Jun; 18(1):100. PubMed ID: 32576198
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
    Martínez-Chantar ML; Vázquez-Chantada M; Ariz U; Martínez N; Varela M; Luka Z; Capdevila A; Rodríguez J; Aransay AM; Matthiesen R; Yang H; Calvisi DF; Esteller M; Fraga M; Lu SC; Wagner C; Mato JM
    Hepatology; 2008 Apr; 47(4):1191-9. PubMed ID: 18318442
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CSIG promotes hepatocellular carcinoma proliferation by activating c-MYC expression.
    Cheng Q; Yuan F; Lu F; Zhang B; Chen T; Chen X; Cheng Y; Li N; Ma L; Tong T
    Oncotarget; 2015 Mar; 6(7):4733-44. PubMed ID: 25749381
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.