248 related articles for article (PubMed ID: 30765302)
1. Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease.
de Andrade P; Mantoani SP; Gonçalves Nunes PS; Magadán CR; Pérez C; Xavier DJ; Hojo ETS; Campillo NE; Martínez A; Carvalho I
Bioorg Med Chem; 2019 Mar; 27(6):931-943. PubMed ID: 30765302
[TBL] [Abstract][Full Text] [Related]
2. Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids.
Bautista-Aguilera OM; Esteban G; Chioua M; Nikolic K; Agbaba D; Moraleda I; Iriepa I; Soriano E; Samadi A; Unzeta M; Marco-Contelles J
Drug Des Devel Ther; 2014; 8():1893-910. PubMed ID: 25378907
[TBL] [Abstract][Full Text] [Related]
3. Novel coumarin-3-carboxamides bearing N-benzylpiperidine moiety as potent acetylcholinesterase inhibitors.
Asadipour A; Alipour M; Jafari M; Khoobi M; Emami S; Nadri H; Sakhteman A; Moradi A; Sheibani V; Homayouni Moghadam F; Shafiee A; Foroumadi A
Eur J Med Chem; 2013; 70():623-30. PubMed ID: 24211638
[TBL] [Abstract][Full Text] [Related]
4. Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors.
Chierrito TPC; Pedersoli-Mantoani S; Roca C; Sebastian-Pérez V; Martínez-Gonzalez L; Pérez DI; Perez C; Canales A; Cañada FJ; Campillo NE; Carvalho I; Martinez A
Eur J Med Chem; 2018 Feb; 145():431-444. PubMed ID: 29335209
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.
Xie SS; Lan JS; Wang X; Wang ZM; Jiang N; Li F; Wu JJ; Wang J; Kong LY
Bioorg Med Chem; 2016 Apr; 24(7):1528-39. PubMed ID: 26917219
[TBL] [Abstract][Full Text] [Related]
6. Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: synthesis, biological assessment, and molecular modeling.
Samadi A; Estrada M; Pérez C; Rodríguez-Franco MI; Iriepa I; Moraleda I; Chioua M; Marco-Contelles J
Eur J Med Chem; 2012 Nov; 57():296-301. PubMed ID: 23078965
[TBL] [Abstract][Full Text] [Related]
7. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Bolea I; Juárez-Jiménez J; de Los Ríos C; Chioua M; Pouplana R; Luque FJ; Unzeta M; Marco-Contelles J; Samadi A
J Med Chem; 2011 Dec; 54(24):8251-70. PubMed ID: 22023459
[TBL] [Abstract][Full Text] [Related]
8. Search for new multi-target compounds against Alzheimer's disease among histamine H
Bajda M; Łażewska D; Godyń J; Zaręba P; Kuder K; Hagenow S; Łątka K; Stawarska E; Stark H; Kieć-Kononowicz K; Malawska B
Eur J Med Chem; 2020 Jan; 185():111785. PubMed ID: 31669851
[TBL] [Abstract][Full Text] [Related]
9. Novel N-benzylpiperidine derivatives of 5-arylisoxazole-3-carboxamides as anti-Alzheimer's agents.
Saeedi M; Felegari P; Iraji A; Hariri R; Rastegari A; Mirfazli SS; Edraki N; Firuzi O; Mahdavi M; Akbarzadeh T
Arch Pharm (Weinheim); 2021 Mar; 354(3):e2000258. PubMed ID: 33226157
[TBL] [Abstract][Full Text] [Related]
10. Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase.
Rodríguez-Franco MI; Fernández-Bachiller MI; Pérez C; Castro A; Martínez A
Bioorg Med Chem; 2005 Dec; 13(24):6795-802. PubMed ID: 16183292
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin.
Wang J; Wang ZM; Li XM; Li F; Wu JJ; Kong LY; Wang XB
Bioorg Med Chem; 2016 Sep; 24(18):4324-4338. PubMed ID: 27460699
[TBL] [Abstract][Full Text] [Related]
12. Design, Synthesis, and Biological Evaluation of a New Series of Biphenyl/Bibenzyl Derivatives Functioning as Dual Inhibitors of Acetylcholinesterase and Butyrylcholinesterase.
Wang DM; Feng B; Fu H; Liu AL; Wang L; Du GH; Wu S
Molecules; 2017 Jan; 22(1):. PubMed ID: 28117700
[TBL] [Abstract][Full Text] [Related]
13. Novel N-benzylpiperidine carboxamide derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease.
van Greunen DG; Johan van der Westhuizen C; Cordier W; Nell M; Stander A; Steenkamp V; Panayides JL; Riley DL
Eur J Med Chem; 2019 Oct; 179():680-693. PubMed ID: 31280020
[TBL] [Abstract][Full Text] [Related]
14. Discovery of δ-sultone-fused pyrazoles for treating Alzheimer's disease: Design, synthesis, biological evaluation and SAR studies.
Xu Y; Zhang Z; Jiang X; Chen X; Wang Z; Alsulami H; Qin HL; Tang W
Eur J Med Chem; 2019 Nov; 181():111598. PubMed ID: 31415981
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, biological evaluation, and molecular dynamics of novel cholinesterase inhibitors as anti-Alzheimer's agents.
Shamsimeymandi R; Pourshojaei Y; Eskandari K; Mohammadi-Khanaposhtani M; Abiri A; Khodadadi A; Langarizadeh A; Sharififar F; Amirheidari B; Akbarzadeh T; Lotfian H; Foroumadi A; Asadipour A
Arch Pharm (Weinheim); 2019 Jul; 352(7):e1800352. PubMed ID: 31136018
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
Li F; Wang ZM; Wu JJ; Wang J; Xie SS; Lan JS; Xu W; Kong LY; Wang XB
J Enzyme Inhib Med Chem; 2016; 31(sup3):41-53. PubMed ID: 27384289
[TBL] [Abstract][Full Text] [Related]
17. Syntheses, cholinesterases inhibition, and molecular docking studies of pyrido[2,3-b]pyrazine derivatives.
Hameed A; Zehra ST; Shah SJ; Khan KM; Alharthy RD; Furtmann N; Bajorath J; Tahir MN; Iqbal J
Chem Biol Drug Des; 2015 Nov; 86(5):1115-20. PubMed ID: 25951978
[TBL] [Abstract][Full Text] [Related]
18. Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors.
Więckowska A; Bajda M; Guzior N; Malawska B
Eur J Med Chem; 2010 Dec; 45(12):5602-11. PubMed ID: 20926161
[TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of benzodiazepine-1,2,3-triazole hybrid derivatives as selective butyrylcholinesterase inhibitors.
Mehrazar M; Hassankalhori M; Toolabi M; Goli F; Moghimi S; Nadri H; Bukhari SNA; Firoozpour L; Foroumadi A
Mol Divers; 2020 Nov; 24(4):997-1013. PubMed ID: 31845210
[TBL] [Abstract][Full Text] [Related]
20. Discovery of methoxy-naphthyl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase.
Abdullaha M; Nuthakki VK; Bharate SB
Eur J Med Chem; 2020 Dec; 207():112761. PubMed ID: 32942070
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]