BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 30771432)

  • 1. Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells.
    Feng Y; Sessions EH; Zhang F; Ban F; Placencio-Hickok V; Ma CT; Zeng FY; Pass I; Terry DB; Cadwell G; Bankston LA; Liddington RC; Chung TDY; Pinkerton AB; Sergienko E; Gleave M; Bhowmick NA; Jackson MR; Cherkasov A; Ronai ZA
    Cancer Lett; 2019 May; 449():145-162. PubMed ID: 30771432
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status.
    Adam MG; Matt S; Christian S; Hess-Stumpp H; Haegebarth A; Hofmann TG; Algire C
    Cell Cycle; 2015; 14(23):3734-47. PubMed ID: 26654769
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers.
    Knauer SK; Mahendrarajah N; Roos WP; Krämer OH
    Cytokine Growth Factor Rev; 2015 Aug; 26(4):405-13. PubMed ID: 26028498
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phylogenetic analysis of the SINA/SIAH ubiquitin E3 ligase family in Metazoa.
    Pepper IJ; Van Sciver RE; Tang AH
    BMC Evol Biol; 2017 Aug; 17(1):182. PubMed ID: 28784114
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells.
    Quirit JG; Lavrenov SN; Poindexter K; Xu J; Kyauk C; Durkin KA; Aronchik I; Tomasiak T; Solomatin YA; Preobrazhenskaya MN; Firestone GL
    Biochem Pharmacol; 2017 Mar; 127():13-27. PubMed ID: 27979631
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DHX15 promotes prostate cancer progression by stimulating Siah2-mediated ubiquitination of androgen receptor.
    Jing Y; Nguyen MM; Wang D; Pascal LE; Guo W; Xu Y; Ai J; Deng FM; Masoodi KZ; Yu X; Zhang J; Nelson JB; Xia S; Wang Z
    Oncogene; 2018 Feb; 37(5):638-650. PubMed ID: 28991234
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The substrate binding domains of human SIAH E3 ubiquitin ligases are now crystal clear.
    Zhang Q; Wang Z; Hou F; Harding R; Huang X; Dong A; Walker JR; Tong Y
    Biochim Biophys Acta Gen Subj; 2017 Jan; 1861(1 Pt A):3095-3105. PubMed ID: 27776223
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of Siah2 ubiquitin ligase by vitamin K3 (menadione) attenuates hypoxia and MAPK signaling and blocks melanoma tumorigenesis.
    Shah M; Stebbins JL; Dewing A; Qi J; Pellecchia M; Ronai ZA
    Pigment Cell Melanoma Res; 2009 Dec; 22(6):799-808. PubMed ID: 19712206
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Investigating the molecular basis of Siah1 and Siah2 E3 ubiquitin ligase substrate specificity.
    Gopalsamy A; Hagen T; Swaminathan K
    PLoS One; 2014; 9(9):e106547. PubMed ID: 25202994
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MiR-107 down-regulates SIAH1 expression in human breast cancer cells and silencing of miR-107 inhibits tumor growth in a nude mouse model of triple-negative breast cancer.
    Zhang L; Ma P; Sun LM; Han YC; Li BL; Mi XY; Wang EH; Song M
    Mol Carcinog; 2016 May; 55(5):768-77. PubMed ID: 25851994
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The SIAH1-HIPK2-p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death.
    He Y; Roos WP; Wu Q; Hofmann TG; Kaina B
    Mol Cancer Res; 2019 May; 17(5):1129-1141. PubMed ID: 30796178
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH.
    Christian PA; Fiandalo MV; Schwarze SR
    Mol Cancer; 2011 May; 10():57. PubMed ID: 21586138
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of tankyrase by a novel small molecule significantly attenuates prostate cancer cell proliferation.
    Cheng H; Li X; Wang C; Chen Y; Li S; Tan J; Tan B; He Y
    Cancer Lett; 2019 Feb; 443():80-90. PubMed ID: 30472184
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle.
    Dogan T; Gnad F; Chan J; Phu L; Young A; Chen MJ; Doll S; Stokes MP; Belvin M; Friedman LS; Kirkpatrick DS; Hoeflich KP; Hatzivassiliou G
    J Biol Chem; 2017 Sep; 292(35):14311-14324. PubMed ID: 28655764
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Downregulation of the Arg/N-degron Pathway Sensitizes Cancer Cells to Chemotherapy In Vivo.
    Leboeuf D; Abakumova T; Prikazchikova T; Rhym L; Anderson DG; Zatsepin TS; Piatkov KI
    Mol Ther; 2020 Apr; 28(4):1092-1104. PubMed ID: 32087767
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion.
    Scortegagna M; Berthon A; Settas N; Giannakou A; Garcia G; Li JL; James B; Liddington RC; Vilches-Moure JG; Stratakis CA; Ronai ZA
    JCI Insight; 2017 Dec; 2(23):. PubMed ID: 29212953
    [TBL] [Abstract][Full Text] [Related]  

  • 17. De novo variants in
    Buratti J; Ji L; Keren B; Lee Y; Booke S; Erdin S; Kim SY; Palculict TB; Meiner V; Chae JH; Woods CG; Tam A; Héron D; Cong F; Harel T
    J Med Genet; 2021 Mar; 58(3):205-212. PubMed ID: 32430360
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.
    Zhang J; Lei Z; Huang Z; Zhang X; Zhou Y; Luo Z; Zeng W; Su J; Peng C; Chen X
    Oncotarget; 2016 Nov; 7(48):79557-79571. PubMed ID: 27791197
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Upregulation of Circular RNA Itchy E3 Ubiquitin Protein Ligase Inhibits Cell Proliferation and Promotes Cell Apoptosis Through Targeting MiR-197 in Prostate Cancer.
    Yuan Y; Chen X; Huang E
    Technol Cancer Res Treat; 2019; 18():1533033819886867. PubMed ID: 31694481
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and pharmacological screening of a large library of 1,3,4-thiadiazolines as innovative therapeutic tools for the treatment of prostate cancer and melanoma.
    De Monte C; Carradori S; Secci D; D'Ascenzio M; Guglielmi P; Mollica A; Morrone S; Scarpa S; Aglianò AM; Giantulli S; Silvestri I
    Eur J Med Chem; 2015 Nov; 105():245-62. PubMed ID: 26498571
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.